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Slc36a4 Gene Detail
Summary
  • Symbol
    Slc36a4
  • Name
    solute carrier family 36 (proton/amino acid symporter), member 4
  • Synonyms
    6330573I15Rik, PAT4
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442595
    NCBI Gene: 234967
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:15709738-15742388 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 5.12 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    123 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442595
protein coding gene Chr9:15709738-15743361 (+)
129S1/SvImJ MGP_129S1SvImJ_G0034368
protein coding gene Chr9:12710358-12740124 (+)
A/J MGP_AJ_G0034346
protein coding gene Chr9:12627275-12659467 (+)
AKR/J MGP_AKRJ_G0034274
protein coding gene Chr9:12667112-12699262 (+)
BALB/cJ MGP_BALBcJ_G0034340
protein coding gene Chr9:12410152-12442188 (+)
C3H/HeJ MGP_C3HHeJ_G0034051
protein coding gene Chr9:12981690-13013882 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034862
protein coding gene Chr9:13123609-13153579 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031800
protein coding gene Chr9:11890218-11923298 (+)
CAST/EiJ MGP_CASTEiJ_G0033378
protein coding gene Chr9:12833627-12871841 (+)
CBA/J MGP_CBAJ_G0034024
protein coding gene Chr9:13744789-13778523 (+)
DBA/2J MGP_DBA2J_G0034181
protein coding gene Chr9:12494960-12527152 (+)
FVB/NJ MGP_FVBNJ_G0034126
protein coding gene Chr9:12077744-12109785 (+)
LP/J MGP_LPJ_G0034267
protein coding gene Chr9:12817263-12850739 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034170
protein coding gene Chr9:14747296-14777525 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034881
protein coding gene Chr9:12705790-12734953 (+)
PWK/PhJ MGP_PWKPhJ_G0033084
protein coding gene Chr9:12576805-12635957 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032919
protein coding gene Chr9:12813219-12850995 (+)
WSB/EiJ MGP_WSBEiJ_G0033494
protein coding gene Chr9:12535339-12569018 (+)



Homology
more
  • Human Ortholog
    SLC36A4, solute carrier family 36 member 4
  • Vertebrate Orthologs
    9
  • Human Ortholog
    SLC36A4, solute carrier family 36 member 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    PAT4
  • Links
    NCBI Gene ID: 120103
    neXtProt AC: NX_Q6YBV0
    UniProt: Q6YBV0

  • Chr Location
    11q21; chr11:93144171-93197983 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 234967 NCBI Gene Model | MGI Sequence Detail 32651 C57BL/6J ±  kb
transcript NM_172289 RefSeq | MGI Sequence Detail 5567 C57BL/6  
polypeptide Q8CH36 UniProt | EBI | MGI Sequence Detail 500 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 33
    cDNA 30
    Primer pair 2
    Other 1

    Microarray probesets 1
References
more
  • Summaries
    All 24
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 3
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:240969 Shang P, et al., The amino acid transporter SLC36A4 regulates the amino acid pool in retinal pigmented epithelial cells and mediates the mechanistic target of rapamycin, complex 1 signaling. Aging Cell. 2017 Apr;16(2):349-359

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory