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Sphkap Gene Detail
Summary
  • Symbol
    Sphkap
  • Name
    SPHK1 interactor, AKAP domain containing
  • Synonyms
    4930544G21Rik, A930009L15Rik, mKIAA1678, SKIP
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924879
    NCBI Gene: 77629
  • Alliance
    gene page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:83255442-83408393 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 42.73 cM, cytoband C5
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    798 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924879
 protein coding gene Chr1:83254139-83408393 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016225
 protein coding gene Chr1:84231487-84390370 (-)
A/J MGP_AJ_G0016208
 protein coding gene Chr1:81227122-81384877 (-)
AKR/J MGP_AKRJ_G0016165
 protein coding gene Chr1:83436282-83601276 (-)
BALB/cJ MGP_BALBcJ_G0016163
 protein coding gene Chr1:81373391-81526741 (-)
C3H/HeJ MGP_C3HHeJ_G0015993
 protein coding gene Chr1:83814392-83985964 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016616
 protein coding gene Chr1:87484471-87658814 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014336
 protein coding gene Chr1:76414240-76555801 (-)
CAST/EiJ MGP_CASTEiJ_G0015578
 protein coding gene Chr1:83255544-83414019 (-)
CBA/J MGP_CBAJ_G0015967
 protein coding gene Chr1:90272141-90455704 (-)
DBA/2J MGP_DBA2J_G0016068
 protein coding gene Chr1:80491882-80646878 (-)
FVB/NJ MGP_FVBNJ_G0016071
 protein coding gene Chr1:79614021-79767327 (-)
LP/J MGP_LPJ_G0016141
 protein coding gene Chr1:85331675-85486592 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016091
 protein coding gene Chr1:93632312-93799874 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016663
 protein coding gene Chr1:83618576-83782525 (-)
PWK/PhJ MGP_PWKPhJ_G0015364
 protein coding gene Chr1:79953360-80110934 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015142
 protein coding gene Chr1:82804916-82952561 (-)
WSB/EiJ MGP_WSBEiJ_G0015639
 protein coding gene Chr1:83400615-83555800 (-)



Homology
more
  • Human Ortholog
    SPHKAP, SPHK1 interactor, AKAP domain containing
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SPHKAP, SPHK1 interactor, AKAP domain containing
    Orthology source: HomoloGene, HGNC
  • Synonyms
    SKIP
  • Links
    NCBI Gene ID: 80309
    neXtProt AC: NX_Q2M3C7
    UniProt: Q2M3C7

  • Chr Location
    2q36.3; chr2:227979954-228181999 (-)  GRCh38.p7
  • HomoloGene
    Vertebrate Homology Class 18172
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: SPHKAP
  • Gene Tree
    Sphkap
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    137
  • Tissues
    25
  • cDNA Data
    13
  • Literature Summary
    6
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 77629 NCBI Gene Model | MGI Sequence Detail 152952 C57BL/6J ±  kb
transcript NM_001356547 RefSeq | MGI Sequence Detail 6930 C57BL/6  
polypeptide Q6NSW3 UniProt | EBI | MGI Sequence Detail 1687 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR018292 A-kinase anchor 110kDa, C-terminal
    IPR008382 SPHK1-interactor/A-kinase anchor 110kDa
Molecular
Reagents
less
  • All nucleic 16
    cDNA 14
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGI:1925196, MGI:2138360
References
more
  • Summaries
    All 33
    Developmental Gene Expression 6
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:226616 Araujo DJ, et al., FoxP1 orchestration of ASD-relevant signaling pathways in the striatum. Genes Dev. 2015 Oct 15;29(20):2081-96
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/19/2019
MGI 6.13 		The Jackson Laboratory