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Kcnt1
Gene Detail
Symbol

Name
ID
Kcnt1
potassium channel, subfamily T, member 1
MGI:1924627
Synonyms
C030030G16Rik, Slack, slo2
Feature Type
protein coding gene
Genetic Map
Chromosome 2
18.27 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr2:25863795-25918273 bp, + strand
From VEGA annotation of GRCm38

  54479 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:11055  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: KCNT1
Gene Tree: Kcnt1

Human
homologs
KCNT1, potassium channel, sodium activated subfamily T, member 1
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 57582
neXtProt AC: NX_Q5JUK3

Human Synonyms: bA100C15.2, EIEE14, ENFL5, KCa4.1, SLACK, Slo2.2

Human Chr (Location): 9q34.3; chr9:135702185-135793147 (+)  GRCh38.p2

Disease Associations: (2) Diseases Associated with Human KCNT1

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Kcnt1 interacts with 246 markers (Mir1a-1, Mir1a-2, Mir9-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process ion transport, potassium ion transmembrane transport, ...
Component integral component of membrane, membrane, ...
Function calcium-activated potassium channel activity, potassium channel activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (98)    Tissues (14)    Images (21)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 98
cDNA source data(22)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase kcnt2    NEW 
Molecular
reagents
All nucleic(22) cDNA(22)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000012660 (Evidence)
Ensembl Gene Model ENSMUSG00000058740 (Evidence)
Entrez Gene 227632 (Evidence)
UniGene 119462
DFCI TC1646043, TC1592901, TC1581962, TC1602967, TC1646679, TC1768168
DoTS DT.101346554, DT.110662181, DT.101185390, DT.40182318, DT.97402582, DT.97356257, DT.55274402, DT.55201950
NIA Mouse Gene Index U001507
Consensus CDS Project CCDS15794.1, CCDS50537.1
International Mouse Phenotyping Consortium Status Kcnt1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000012660 VEGA Gene Model | MGI Sequence Detail 54479 C57BL/6J ±  kb
transcript OTTMUST00000030153 VEGA | MGI Sequence Detail 5881 Not Applicable 
polypeptide OTTMUSP00000013573 VEGA | MGI Sequence Detail 1238 Not Applicable 

For the selected sequences
All sequences(123) RefSeq(43) UniProt(7)
Polymorphisms
SNPs within 2kb(460 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR013099 Ion transport 2
InterPro IPR016040 NAD(P)-binding domain
InterPro IPR003929 Potassium channel, calcium-activated, BK, alpha subunit
Protein Ontology PR:000002080 potassium channel subfamily T member 1
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(31)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory