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Kcnt1
Gene Detail
 Symbol
Name
ID
Kcnt1
potassium channel, subfamily T, member 1
MGI:1924627
Synonyms C030030G16Rik, Slack, slo2
Feature Type protein coding gene
Genetic Map
Chromosome 2
18.27 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr2:25863795-25918273 bp, + strand
From VEGA annotation of GRCm38

  54479 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:11055  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Kcnt1

Human
homologs
Human Homolog KCNT1, potassium channel, subfamily T, member 1
NCBI Gene ID 57582
neXtProt AC  NX_Q5JUK3
Human Synonyms  bA100C15.2, EIEE14, ENFL5, KCa4.1, SLACK
Human Chr (Location)  9q34.3; chr9:135702185-135793147 (+)  GRCh38
Disease Associations  (2) Diseases Associated with Human KCNT1
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Kcnt1 interacts with 247 markers (Mir1a-1, Mir1a-2, Mir9-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process ion transport, potassium ion transmembrane transport, ...
Component integral component of membrane, membrane, ...
Function calcium-activated potassium channel activity, potassium channel activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (98)    Tissues (14)    Images (21)
Theiler Stages: 23
Assay TypeResults
RNA in situ 98
cDNA source data(22)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(22) cDNA(22)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000012660 (Evidence)
Ensembl Gene ModelENSMUSG00000058740 (Evidence)
Entrez Gene227632 (Evidence)
UniGene119462
DFCITC1581962, TC1592901, TC1602967, TC1646679, TC1768168
DoTSDT.101346554, DT.110662181, DT.40182318, DT.55201950, DT.55274402, DT.97356257, DT.97402582
NIA Mouse Gene IndexU001507
Consensus CDS ProjectCCDS15794.1, CCDS50537.1
International Mouse Knockout Project StatusKcnt1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000012660 VEGA Gene Model | MGI Sequence Detail 54479 C57BL/6J ±  kb
transcript OTTMUST00000030153 VEGA | MGI Sequence Detail 5881 Not Applicable 
polypeptide OTTMUSP00000013573 VEGA | MGI Sequence Detail 1238 Not Applicable 

For the selected sequences
All sequences(120) RefSeq(46) UniProt(7)
Polymorphisms SNPs within 2kb(460 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR013099 Ion transport 2
InterPro IPR016040 NAD(P)-binding domain
InterPro IPR003929 Potassium channel, calcium-activated, BK, alpha subunit
Protein Ontology PR:000002080 potassium channel subfamily T member 1
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(32)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory