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Symbol
Name
ID
Kcnt1
potassium channel, subfamily T, member 1
MGI:1924627
Phenotype annotations related to behavior/neurological
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Depression
Atypical behavior
Personality disorder
Aggressive behavior
Disease(s) Associated with KCNT1
autosomal dominant nocturnal frontal lobe epilepsy 5

Mouse Phenotypes
behavior/neurological phenotype
abnormal behavior
impaired contextual conditioning behavior
impaired cued conditioning behavior
decreased exploration in new environment
decreased anxiety-related response
decreased thigmotaxis
increased anxiety-related response
increased thigmotaxis
decreased fear-related response
decreased locomotor activity
hyperactivity
abnormal mechanical nociception
abnormal nest building behavior
seizures
tonic seizures
tonic-clonic seizures
Availability Mouse Genotype
Kcnt1em1(IMPC)Mbp/Kcnt1em1(IMPC)Mbp
Kcnt1em1Nju/Kcnt1em1Nju *
Kcnt1em1Pqt/Kcnt1em1Pqt
Kcnt1em8Frk/Kcnt1em8Frk *
Kcnt1tm1.2Acsc/Kcnt1tm1.2Acsc
Kcnt1tm1Dgen/Kcnt1tm1Dgen *
Kcnt1em1Pqt/Kcnt1+ *
Kcnt1tm1.1Acsc/Kcnt1tm1.1Acsc
Tg(Scn10a-cre)1Rkun/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory