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Rps7 Gene Detail
Summary
  • Symbol
    Rps7
  • Name
    ribosomal protein S7
  • Synonyms
    Mtu, S7
  • Feature Type
    protein coding gene
  • IDs
    MGI:1333818
    NCBI Gene: 20115
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:28680853-28685952 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 12, 10.99 cM, cytoband C1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    135 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1333818
protein coding gene Chr12:28680846-28685952 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019643
protein coding gene Chr12:26465732-26471184 (-)
A/J MGP_AJ_G0019610
protein coding gene Chr12:25754384-25759495 (-)
AKR/J MGP_AKRJ_G0019581
protein coding gene Chr12:26614310-26619422 (-)
BALB/cJ MGP_BALBcJ_G0019587
protein coding gene Chr12:26005425-26010531 (-)
C3H/HeJ MGP_C3HHeJ_G0019391
protein coding gene Chr12:26473956-26479067 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020034
protein coding gene Chr12:27319497-27324595 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017659
protein coding gene Chr12:25111069-25116523 (-)
CAST/EiJ MGP_CASTEiJ_G0018946
protein coding gene Chr12:21439031-21444375 (-)
CBA/J MGP_CBAJ_G0019362
protein coding gene Chr12:28281207-28286318 (-)
DBA/2J MGP_DBA2J_G0019476
protein coding gene Chr12:25606517-25611642 (-)
FVB/NJ MGP_FVBNJ_G0019467
protein coding gene Chr12:25407729-25412840 (-)
LP/J MGP_LPJ_G0019546
protein coding gene Chr12:26553684-26558797 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019502
protein coding gene Chr12:27909343-27914907 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020074
protein coding gene Chr12:26132413-26137538 (-)
PWK/PhJ MGP_PWKPhJ_G0018713
protein coding gene Chr12:20312550-20317699 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018501
protein coding gene Chr12:20710963-20716064 (-)
WSB/EiJ MGP_WSBEiJ_G0018997
protein coding gene Chr12:26334596-26339732 (-)



Homology
more
  • Human Ortholog
    RPS7, ribosomal protein S7
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RPS7, ribosomal protein S7
  • Synonyms
    DBA8, eS7, S7
  • Links
    NCBI Gene ID: 6201
    neXtProt AC: NX_P62081
    UniProt: P62081

  • Chr Location
    2p25.3; chr2:3575260-3580920 (+)  GRCh38

Human Diseases
more
  • Diseases
    1 with human RPS7 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    33 phenotypes from 2 alleles in 5 genetic backgrounds
    11 phenotypes from multigenic genotypes
    10 images
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice heterozygous for this ENU-induced mutation exhibit a white ventral patch and an extremely kinked or looped tail. Homozygotes exhibit an open hindbrain and defective neural crest production at E9.5.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
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    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000061477 Ensembl Gene Model | MGI Sequence Detail 5100 C57BL/6J ±  kb
    transcript ENSMUST00000074267 Ensembl | MGI Sequence Detail 954 Not Applicable  
    polypeptide ENSMUSP00000073880 Ensembl | MGI Sequence Detail 194 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 15
      Genomic 1
      cDNA 13
      Primer pair 1

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:3043038
    References
    more
    • Summaries
      All 37
      Developmental Gene Expression 5
      Gene Ontology 10
      Phenotypes 6
    • Earliest
      J:51004 Annilo T, et al., Isolation and characterization of the mouse ribosomal protein S7 gene. Biochem Mol Biol Int. 1998 Oct;46(2):287-95
    • Latest
      J:333015 Li H, et al., A male germ-cell-specific ribosome controls male fertility. Nature. 2022 Dec;612(7941):725-731

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    03/12/2024
    MGI 6.23
    The Jackson Laboratory