Mapping Data Summary

• Symbol: Ifna
• Name: interferon alpha
• ID: MGI:107670
• Chromosome: 4

85 mapping experiments

Experiment Type	Details	Chromosome	Reference
CROSS	Cross Type: Backcross	4	J:10819 Bahary N, et al., Molecular mapping of the mouse db mutation. Proc Natl Acad Sci U S A. 1990 Nov;87(21):8642-6
CROSS	Cross Type: Backcross	4	J:10819 Bahary N, et al., Molecular mapping of the mouse db mutation. Proc Natl Acad Sci U S A. 1990 Nov;87(21):8642-6
CROSS	Cross Type: Backcross	4	J:10819 Bahary N, et al., Molecular mapping of the mouse db mutation. Proc Natl Acad Sci U S A. 1990 Nov;87(21):8642-6
CROSS	Cross Type: Backcross	4	J:4362 Bahary N, et al., Microdissection and microcloning of mid-chromosome 4: genetic mapping of 41 microdissection clones. Genomics. 1993 Apr;16(1):113-22
CROSS	Cross Type: Backcross	4	J:4362 Bahary N, et al., Microdissection and microcloning of mid-chromosome 4: genetic mapping of 41 microdissection clones. Genomics. 1993 Apr;16(1):113-22
CROSS	Cross Type: Backcross	4	J:4362 Bahary N, et al., Microdissection and microcloning of mid-chromosome 4: genetic mapping of 41 microdissection clones. Genomics. 1993 Apr;16(1):113-22
CROSS	Cross Type: Backcross	4	J:3321 Bahary N, et al., Molecular genetic linkage maps of mouse chromosomes 4 and 6. Genomics. 1991 Sep;11(1):33-47
CROSS	Cross Type: Backcross	4	J:2643 Beier DR, et al., Mapping genes in the mouse using single-strand conformation polymorphism analysis of recombinant inbred strains and interspecific crosses. Proc Natl Acad Sci U S A. 1992 Oct 1;89(19):9102-6
CROSS	Cross Type: Backcross	4	J:10133 Ceci JD, et al., A molecular genetic linkage map of mouse chromosome 4 including the localization of several proto-oncogenes. Genomics. 1989 Nov;5(4):699-709
CROSS	Cross Type: Backcross	4	J:7993 Dandoy F, et al., Segregation of restriction fragment length polymorphism in an interspecies cross of laboratory and wild mice indicates tight linkage of the murine IFN-beta gene to the murine IFN-alpha genes. J Virol. 1985 Oct;56(1):216-20
CROSS	Cross Type: Backcross	4	J:8810 De Maeyer E, et al., Linkage analysis of the murine interferon alpha locus (Ifa) on chromosome 4. J Hered. 1987 May-Jun;78(3):143-6
CROSS	Cross Type: Backcross	4	J:8810 De Maeyer E, et al., Linkage analysis of the murine interferon alpha locus (Ifa) on chromosome 4. J Hered. 1987 May-Jun;78(3):143-6
CROSS	Cross Type: Backcross	4	J:11192 Fletcher C, et al., Genetic mapping of meander tail, a mouse mutation affecting cerebellar development. Genomics. 1991 Apr;9(4):647-55
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	4	J:54120 Fletcher CF, et al., Exon structure of the nuclear factor I DNA-binding domain from C. elegans to mammals. Mamm Genome. 1999 Apr;10(4):390-6
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	4	J:40255 Fletcher CF, et al., Mouse chromosomal locations of nine genes encoding homologs of human paraneoplastic neurologic disorder antigens. Genomics. 1997 Oct 15;45(2):313-9
CROSS	Cross Type: Backcross	4	J:36 Greenfield AJ, et al., Mappping of clone D4Smh6b to the distal end of mouse chromosome 4. Mouse Genome. 1992;90(1):94-95
CROSS	Cross Type: Backcross	4	J:1694 Hanley-Hyde J, et al., Expression of murine cyclin B1 mRNAs and genetic mapping of related genomic sequences. Genomics. 1992 Aug;13(4):1018-30
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	4	J:2951 Hogan A, et al., Glucose transporter gene expression in early mouse embryos. Development. 1991 Sep;113(1):363-72
CROSS	Cross Type: Backcross	4	J:4474 Huppi K, et al., Organization of the distal end of mouse chromosome 4. Curr Top Microbiol Immunol. 1988;137:276-88
CROSS	Cross Type: Backcross	4	J:3223 Krall M, et al., Isolation and mapping of four new DNA markers from mouse chromosome 4. Mamm Genome. 1992;3(11):653-5
CROSS	Cross Type: Backcross Mapping Panel: Kozak FvC58 + FvSpr	4	J:54005 Lee CG, et al., Genetic mapping of eight SH3 domain genes on seven mouse chromosomes. Mamm Genome. 1999 Apr;10(4):402-4
CROSS	Cross Type: Backcross Mapping Panel: Kozak Skive (C58/J or NFS/N)	4	J:54005 Lee CG, et al., Genetic mapping of eight SH3 domain genes on seven mouse chromosomes. Mamm Genome. 1999 Apr;10(4):402-4
CROSS	Cross Type: Backcross	4	J:47555 Ma J, et al., Mapping of the CYP2J cytochrome P450 genes to human chromosome 1 and mouse chromosome 4. Genomics. 1998 Apr 1;49(1):152-5
CROSS	Cross Type: Backcross	4	J:8569 Nadeau JH, et al., Rearrangement of genes located on homologous chromosomal segments in mouse and man: the location of genes for alpha- and beta-interferon, alpha-1 acid glycoprotein-1 and -2, and aminolevulinate dehydratase on mouse chromosome 4. Genetics. 1986 Dec;114(4):1239-55
CROSS	Cross Type: Backcross	4	J:8569 Nadeau JH, et al., Rearrangement of genes located on homologous chromosomal segments in mouse and man: the location of genes for alpha- and beta-interferon, alpha-1 acid glycoprotein-1 and -2, and aminolevulinate dehydratase on mouse chromosome 4. Genetics. 1986 Dec;114(4):1239-55
CROSS	Cross Type: Backcross	4	J:73819 Ohtoshi A, et al., Dmbx1, a novel evolutionarily conserved paired-like homeobox gene expressed in the brain of mouse embryos. Mech Dev. 2002 Jan;110(1-2):241-4
CROSS	Cross Type: Backcross	4	J:43480 Peiffer-Schneider S, et al., Exclusion of Ifa and Ifb as the Lps gene and mapping of three markers near the Lps locus. Mamm Genome. 1997 Oct;8(10):785-6
CROSS	Cross Type: Backcross	4	J:16165 Pilz A, et al., Linkage mapping of the Aldo-2, Pax-5, Ambp, and D4h9S3E loci on mouse chromosome 4 in the region of homology with human chromosome 9. Genomics. 1993 Dec;18(3):705-8
CROSS	Cross Type: Backcross	4	J:22833 Pilz A, et al., Comparative mapping of 50 human chromosome 9 loci in the laboratory mouse. Genomics. 1995 Jan 1;25(1):139-49
CROSS	Cross Type: Backcross Mapping Panel: Kozak Skive	4	J:15180 Sato TN, et al., Tie-1 and tie-2 define another class of putative receptor tyrosine kinase genes expressed in early embryonic vascular system [published erratum appears in Proc Natl Acad Sci U S A 1993 Dec 15;90(24):12056]. Proc Natl Acad Sci U S A. 1993 Oct 15;90(20):9355-8
CROSS	Cross Type: Backcross Mapping Panel: Kozak FvC58 + FvSpr	4	J:15180 Sato TN, et al., Tie-1 and tie-2 define another class of putative receptor tyrosine kinase genes expressed in early embryonic vascular system [published erratum appears in Proc Natl Acad Sci U S A 1993 Dec 15;90(24):12056]. Proc Natl Acad Sci U S A. 1993 Oct 15;90(20):9355-8
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	4	J:11120 Siracusa LD, et al., Identification and applications of repetitive probes for gene mapping in the mouse. Genetics. 1991 Jan;127(1):169-79
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	4	J:47650 Stanley E, et al., Murine cerberus homologue Cer1 maps to chromosome 4. Genomics. 1998 Apr 15;49(2):337-8
CROSS	Cross Type: Backcross	4	J:20143 Warman ML, et al., The genes encoding alpha 2(IX) collagen (COL9A2) map to human chromosome 1p32.3-p33 and mouse chromosome 4. Genomics. 1994 Sep 1;23(1):158-62
CROSS	Cross Type: Backcross	4	J:46172 Zhang S, et al., Cdkn2a, the cyclin-dependent kinase inhibitor encoding p16INK4a and p19ARF, is a candidate for the plasmacytoma susceptibility locus, Pctr1. Proc Natl Acad Sci U S A. 1998 Mar 3;95(5):2429-34
HYBRID		4	J:7380 Kelley KA, et al., Mapping of murine interferon-alpha genes to chromosome 4. Gene. 1983 Dec;26(2-3):181-8
HYBRID		4	J:7503 Lovett M, et al., The chromosomal location of mouse interferon alpha genes. EMBO J. 1984 Jul;3(7):1643-6
HYBRID		4	J:7746 van der Korput JA, et al., Mouse interferon alpha and beta genes are linked at the centromere proximal region of chromosome 4. J Gen Virol. 1985 Mar;66(Pt 3):493-502
HYBRID		4	J:7746 van der Korput JA, et al., Mouse interferon alpha and beta genes are linked at the centromere proximal region of chromosome 4. J Gen Virol. 1985 Mar;66(Pt 3):493-502
IN SITU	Band: C5	4	J:8072 Cahilly LA, et al., Subchromosomal localization of mouse IFN-alpha genes by in situ hybridization. J Interferon Res. 1985 Summer;5(3):391-5
IN SITU	Band: C3-C6	4	J:8226 Cheng ZY, et al., The mouse IFN-alpha (Ifa) locus: correlation of physical and linkage maps by in situ hybridization. Cytogenet Cell Genet. 1986;41(2):101-6
IN SITU	Band: C	4	J:8226 Cheng ZY, et al., The mouse IFN-alpha (Ifa) locus: correlation of physical and linkage maps by in situ hybridization. Cytogenet Cell Genet. 1986;41(2):101-6
RI	RI/RC Set: CXB	4	J:10980 Begley CG, et al., Molecular cloning and chromosomal localization of the murine homolog of the human helix-loop-helix gene SCL. Proc Natl Acad Sci U S A. 1991 Feb 1;88(3):869-73
RI	RI/RC Set: BXD	4	J:2643 Beier DR, et al., Mapping genes in the mouse using single-strand conformation polymorphism analysis of recombinant inbred strains and interspecific crosses. Proc Natl Acad Sci U S A. 1992 Oct 1;89(19):9102-6
RI	RI/RC Set: BXH	4	J:14517 Berry MJ, et al., Physiological and genetic analyses of inbred mouse strains with a type I iodothyronine 5' deiodinase deficiency. J Clin Invest. 1993 Sep;92(3):1517-28
RI	RI/RC Set: CXB	4	J:14517 Berry MJ, et al., Physiological and genetic analyses of inbred mouse strains with a type I iodothyronine 5' deiodinase deficiency. J Clin Invest. 1993 Sep;92(3):1517-28
RI	RI/RC Set: CXB	4	J:7489 Dandoy F, et al., Linkage analysis of the murine interferon-alpha locus on chromosome 4. J Exp Med. 1984 Jul 1;160(1):294-302
RI	RI/RC Set: BXD	4	J:2503 Elliott RW, et al., High resolution blot analysis of alleles for Glut-1 in RI strains. Mouse Genome. 1992;90(3):428-29
RI	RI/RC Set: BXH	4	J:2503 Elliott RW, et al., High resolution blot analysis of alleles for Glut-1 in RI strains. Mouse Genome. 1992;90(3):428-29
RI	RI/RC Set: BXH	4	J:10087 Fultz MJ, et al., The physical separation of Lps and Ifa loci in BXH recombinant inbred mice. J Immunol. 1989 Nov 1;143(9):3001-6
RI	RI/RC Set: CXB	4	J:4474 Huppi K, et al., Organization of the distal end of mouse chromosome 4. Curr Top Microbiol Immunol. 1988;137:276-88
RI	RI/RC Set: CXS	4	J:4474 Huppi K, et al., Organization of the distal end of mouse chromosome 4. Curr Top Microbiol Immunol. 1988;137:276-88
RI	RI/RC Set: BXD	4	J:4474 Huppi K, et al., Organization of the distal end of mouse chromosome 4. Curr Top Microbiol Immunol. 1988;137:276-88
RI	RI/RC Set: BXH	4	J:21511 Kaushik N, et al., Intracisternal A-type particle elements as genetic markers: detection by repeat element viral element amplified locus-PCR. Mamm Genome. 1994 Nov;5(11):688-95
RI	RI/RC Set: CXS	4	J:21511 Kaushik N, et al., Intracisternal A-type particle elements as genetic markers: detection by repeat element viral element amplified locus-PCR. Mamm Genome. 1994 Nov;5(11):688-95
RI	RI/RC Set: BXD	4	J:10137 Kelly R, et al., Characterization of a highly unstable mouse minisatellite locus: evidence for somatic mutation during early development. Genomics. 1989 Nov;5(4):844-56
RI	RI/RC Set: BXD	4	J:905 Lock LF, et al., A single cyclin A gene and multiple cyclin B1-related sequences are dispersed in the mouse genome. Genomics. 1992 Jun;13(2):415-24
RI	RI/RC Set: BXD	4	J:3879 Lueders KK, et al., Genomic mapping of intracisternal A-particle proviral elements. Mamm Genome. 1993;4(2):69-77
RI	RI/RC Set: BXD	4	J:14172 Mizuno K, et al., MPTP delta, a putative murine homolog of HPTP delta, is expressed in specialized regions of the brain and in the B-cell lineage. Mol Cell Biol. 1993 Sep;13(9):5513-23
RI	RI/RC Set: CXB	4	J:8569 Nadeau JH, et al., Rearrangement of genes located on homologous chromosomal segments in mouse and man: the location of genes for alpha- and beta-interferon, alpha-1 acid glycoprotein-1 and -2, and aminolevulinate dehydratase on mouse chromosome 4. Genetics. 1986 Dec;114(4):1239-55
RI	RI/RC Set: BXD	4	J:8569 Nadeau JH, et al., Rearrangement of genes located on homologous chromosomal segments in mouse and man: the location of genes for alpha- and beta-interferon, alpha-1 acid glycoprotein-1 and -2, and aminolevulinate dehydratase on mouse chromosome 4. Genetics. 1986 Dec;114(4):1239-55
RI	RI/RC Set: BXD	4	J:10729 Neumann PE, et al., Identification and mapping of a mouse gene influencing cerebellar folial pattern. Brain Res. 1990 Jul 30;524(1):85-9
RI	RI/RC Set: CXS	4	J:10558 Okumoto M, et al., Genetic analysis of resistance to radiation lymphomagenesis with recombinant inbred strains of mice. Cancer Res. 1990 Jul 1;50(13):3848-50
RI	RI/RC Set: BXD	4	J:12046 Roberts M, et al., Genetic analysis of Leishmania mexicana infection in mice: single gene (Scl-2) controlled predisposition to cutaneous lesion development. J Immunogenet. 1990 Feb-Apr;17(1-2):89-100
TEXT		4	J:38603 Belinsky SA, et al., Deletion and differential expression of p16INK4a in mouse lung tumors. Carcinogenesis. 1997 Jan;18(1):115-20
TEXT		4	J:2365 Gollahon KA, et al., The B6.CE-Lyb-2c:Mup-1a mouse strain contains the interferon-alpha genes from C57BL/6. Immunogenetics. 1992;35(1):62-4
TEXT		4	J:1694 Hanley-Hyde J, et al., Expression of murine cyclin B1 mRNAs and genetic mapping of related genomic sequences. Genomics. 1992 Aug;13(4):1018-30
TEXT		4	J:22054 Hegi ME, et al., Allelotype analysis of mouse lung carcinomas reveals frequent allelic losses on chromosome 4 and an association between allelic imbalances on chromosome 6 and K-ras activation. Cancer Res. 1994 Dec 1;54(23):6257-64
TEXT		4	J:7879 Kelley KA, et al., Characterization of a mouse interferon gene locus I. Isolation of a cluster of four alpha interferon genes. Nucleic Acids Res. 1985 Feb 11;13(3):805-23
TEXT		4	J:18899 Rinchik EM, Molecular genetics of the brown (b)-locus region of mouse chromosome 4. II. Complementation analyses of lethal brown deletions. Genetics. 1994 Jul;137(3):855-65
TEXT		4	J:18898 Rinchik EM, et al., Molecular genetics of the brown (b)-locus region of mouse chromosome 4. I. Origin and molecular mapping of radiation- and chemical-induced lethal brown deletions. Genetics. 1994 Jul;137(3):845-54
TEXT		4	J:71358 Saito Y, et al., Genetic loci controlling susceptibility to gamma-ray-induced thymic lymphoma. Oncogene. 2001 Aug 23;20(37):5243-7
TEXT		4	J:20449 Vogel SN, et al., Construction of a BALB/c congenic mouse, C.C3H-Lpsd, that expresses the Lpsd allele: analysis of chromosome 4 markers surrounding the Lps gene. Infect Immun. 1994 Oct;62(10):4454-9
TEXT-Genetic Cross		4	J:43480 Peiffer-Schneider S, et al., Exclusion of Ifa and Ifb as the Lps gene and mapping of three markers near the Lps locus. Mamm Genome. 1997 Oct;8(10):785-6
TEXT-QTL		4	J:121574 Aly M, et al., Complex genetic control of host susceptibility to coxsackievirus B3-induced myocarditis. Genes Immun. 2007 Apr;8(3):193-204
TEXT-QTL		4	J:125685 Arakura F, et al., Genetic control directed toward spontaneous IFN-alpha/IFN-beta responses and downstream IFN-gamma expression influences the pathogenesis of a murine psoriasis-like skin disease. J Immunol. 2007 Sep 1;179(5):3249-57
TEXT-QTL		4	J:65671 Araujo LM, et al., NKT lymphocyte ontogeny and function are impaired in low antibody-producer Biozzi mice: gene mapping in the interval-specific congenic strains raised for immunomodulatory genes. Int Immunol. 2000 Nov;12(11):1613-22
TEXT-QTL		4	J:108420 Hamano Y, et al., Genetic dissection of vasculitis, myeloperoxidase-specific antineutrophil cytoplasmic autoantibody production, and related traits in spontaneous crescentic glomerulonephritis-forming/Kinjoh mice. J Immunol. 2006 Mar 15;176(6):3662-73
TEXT-QTL		4	J:49899 Ida A, et al., Multigenic control of lupus-associated antiphospholipid syndrome in a model of (NZW x BXSB) F1 mice. Eur J Immunol. 1998 Sep;28(9):2694-703
TEXT-QTL		4	J:73932 Johansson AC, et al., The genetic control of sialadenitis versus arthritis in a NOD.QxB10.Q F2 cross. Eur J Immunol. 2002 Jan;32(1):243-50
TEXT-QTL		4	J:116666 Johansson MH, et al., Mapping of quantitative trait loci determining NK cell-mediated resistance to MHC class I-deficient bone marrow grafts in perforin-deficient mice. J Immunol. 2006 Dec 1;177(11):7923-9
TEXT-QTL		4	J:83433 Nakamura K, et al., Genetic dissection of anxiety in autoimmune disease. Hum Mol Genet. 2003 May 15;12(10):1079-86
TEXT-QTL		4	J:10558 Okumoto M, et al., Genetic analysis of resistance to radiation lymphomagenesis with recombinant inbred strains of mice. Cancer Res. 1990 Jul 1;50(13):3848-50
TEXT-QTL		4	J:16958 Potter M, et al., Identification of two genes on chromosome 4 that determine resistance to plasmacytoma induction in mice. Cancer Res. 1994 Feb 15;54(4):969-75
TEXT-QTL-Candidate Genes		4	J:243935 Ma Y, et al., Borrelia burgdorferi arthritis-associated locus Bbaa1 regulates Lyme arthritis and K/BxN serum transfer arthritis through intrinsic control of type I IFN production. J Immunol. 2014 Dec 15;193(12):6050-60