Mapping Data

Experiment

• Experiment
  TEXT
• Chromosome
  4
• Reference
  J:38603 Belinsky SA, et al., Deletion and differential expression of p16INK4a in mouse lung tumors. Carcinogenesis. 1997 Jan;18(1):115-20
• ID
  MGI:48115

Genes

Gene	Assay Type	Description
D4Mit27	PCR amplified length variant
D4Mit77	PCR amplified length variant
Cdkn2a	PCR amplified length variant	p16-pA, p16-pB
Ifna	reported elsewhere
D17Mit1009	PCR amplified length variant

Notes

• Reference
  Authors refer to Cdkn2a as p16.
• Experiment
  NNK induced lung tumor cell lines that were derived from A/J mice were analyzed for homozygous deletion of microsatellite markers on mouse Chromosome 4. An association of a homozygous deletion of the mouse Chromosome 4 locus Cdkn2a with a deletion of D4Mit77 was observed in a PCR analysis of 15 cell lines. In addition, the deleted region did not include markers D4Mit27 and D4Mit60. The authors show Cdkn2a mapping approximately 12 cMs proximal of Ifna on mouse Chromosome 4.