Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  4
• Reference
  J:16958 Potter M, et al., Identification of two genes on chromosome 4 that determine resistance to plasmacytoma induction in mice. Cancer Res. 1994 Feb 15;54(4):969-75
• ID
  MGI:43595

Genes

Gene	Assay Type
Ifna	reported elsewhere
Cdkn2a	visible phenotype
D4Rck41	reported elsewhere
Tnfrsf1b	reported elsewhere
Pctr2	visible phenotype
D4Smh6b	reported elsewhere

Notes

• Experiment
  BALB/cAnPt mice are susceptibile to plasmacytomas whereas DBA/J mice are resistant. Genetic resistance to plasmacytomas was studied in mice made congenic between BALB/cAnPt and DBA/2N in which chromatin from DBA/2N was transferred to the BALB/cAnPt background. Two regions on Chromosome 4 of DBA/2 are involved in a partial resistant phenotype.
  
  The first region defined by congenics C.D2-Tf3, C.D2-D4Lgm1A, C.D2-D4Lgm1b, C.D2-D4Lgm1C and C.D2-D4Lgm1H is bounded by Ifa and D4Rck41 and is designated Cdkn2a.
  
  The second region defined by congenics C.D2 Fv1 and C.D2 Pnd7 is bounded by Tnfrsf1b and D4Smh6b and designated Pctr2.