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Slc25a53 Gene Detail
Summary
  • Symbol
    Slc25a53
  • Name
    solute carrier family 25, member 53
  • Synonyms
    2310046F18Rik, 2810402A17Rik, Mcart6
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914312
    NCBI Gene: 67062
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:135881865-135939051 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 59.10 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    351 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914312
 protein coding gene ChrX:135881865-135939051 (-)
129S1/SvImJ MGP_129S1SvImJ_G0036111
 protein coding gene ChrX:134389547-134454095 (-)
A/J MGP_AJ_G0036090
 protein coding gene ChrX:133806205-133867228 (-)
AKR/J MGP_AKRJ_G0036014
 protein coding gene ChrX:138091798-138152771 (-)
BALB/cJ MGP_BALBcJ_G0036079
 protein coding gene ChrX:132219156-132278003 (-)
C3H/HeJ MGP_C3HHeJ_G0035787
 protein coding gene ChrX:134439486-134542865 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036604
 protein coding gene ChrX:138326015-138389711 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033429
 protein coding gene ChrX:125730524-125788313 (-)
CAST/EiJ MGP_CASTEiJ_G0035078
 protein coding gene ChrX:115225884-115291651 (-)
CBA/J MGP_CBAJ_G0035764
 protein coding gene ChrX:142569913-142635572 (-)
DBA/2J MGP_DBA2J_G0035921
 protein coding gene ChrX:133098273-133156051 (-)
FVB/NJ MGP_FVBNJ_G0035856
 protein coding gene ChrX:132306636-132365265 (-)
LP/J MGP_LPJ_G0036014
 protein coding gene ChrX:135366720-135458205 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035892
 protein coding gene ChrX:149867982-149931773 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036640
 protein coding gene ChrX:133775052-133831570 (-)
PWK/PhJ MGP_PWKPhJ_G0034771
 protein coding gene ChrX:112249637-112308224 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034598
 protein coding gene ChrX:115835284-115892590 (-)
WSB/EiJ MGP_WSBEiJ_G0035213
 protein coding gene ChrX:132105849-132164454 (-)



Homology
more
  • Human Ortholog
    SLC25A53, solute carrier family 25 member 53
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC25A53, solute carrier family 25 member 53
  • Synonyms
    MCART6
  • Links
    NCBI Gene ID: 401612
    neXtProt AC: NX_Q5H9E4
    UniProt: Q5H9E4

  • Chr Location
    Xq22.2; chrX:104099214-104157009 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    27
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 67062 NCBI Gene Model | MGI Sequence Detail 57187 C57BL/6J ±  kb
transcript NM_001082412 RefSeq | MGI Sequence Detail 3208 C57BL/6  
polypeptide NP_001075881 RefSeq | MGI Sequence Detail 346 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR023395 Mitochondrial carrier domain superfamily
    IPR018108 Mitochondrial substrate/solute carrier
Molecular
Reagents
less
  • All nucleic 27
    cDNA 27

    Microarray probesets 7
Other
Accession IDs
less
MGI:1916896, MGI:2147888, MGI:3035474
References
more
  • Summaries
    All 27
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory