36 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
ApcMin/Apc+ Ptgs2tm1Unc/Ptgs2tm1Unc involves: 129P2/OlaHsd * C57BL/6J	decreased prostaglandin level	J:64401
	decreased tumor incidence	J:64401
	intestine polyps	J:64401
	premature death	J:64401
Apctm1Mmt/Apc+ Ptgs2tm1Jed/Ptgs2+ involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6J	abnormal intestine morphology	J:36816
	colon polyps	J:36816
Apctm1Mmt/Apc+ Ptgs2tm1Jed/Ptgs2tm1Jed involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6J	abnormal intestine morphology	J:36816
Gins4tm1Ntak/Gins4+ Tg(Krt19-Ptgs2,Krt19-Ptges)8Tko/0 Tg(Krt19-Wnt1)2Maos/0 involves: 129P2/OlaHsd * C3H * C57BL/6	decreased tumor growth/size	J:209708
Hmga1tm1Mina/Hmga1tm1Mina Tg(Krt19-Ptgs2,Krt19-Ptges)8Tko/0 Tg(Krt19-Wnt1)2Maos/0 involves: C3H * C57BL/6 * CBA	increased stomach tumor incidence	J:153058
Hrhr/Hrhr Ptgs2tm1Unc/Ptgs2+ involves: 129P2/OlaHsd * C57BL/6 * SKH1	decreased incidence of tumors by UV induction	J:121635
	decreased prostaglandin level	J:121635
	increased cell proliferation	J:121635
Hrhr/Hrhr Ptgs2tm1Unc/Ptgs2tm1Unc involves: 129P2/OlaHsd * C57BL/6 * SKH1	premature death	J:121635
Hrhr/Hrhr Tg(KRT14-Ptgs2)1Sumf/0 involves: C57BL/6 * DBA/2 * FVB/N * SKH1	decreased cell proliferation	J:121635
	increased incidence of tumors by UV-induction	J:121635
	increased prostaglandin level	J:121635
Ptgs1tm1Fun/Ptgs1tm1Fun Ptgs2tm2.1(Ptgs1)Fun/Ptgs2tm2.1(Ptgs1)Fun involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * FVB	prenatal lethality	J:118171
Ptgs1tm1Unc/Ptgs1+ Ptgs2tm1Unc/Ptgs2+ involves: 129P2/OlaHsd * C57BL/6J	delayed parturition	J:67208
Ptgs1tm1Unc/Ptgs1+ Ptgs2tm1Unc/Ptgs2tm1Unc involves: 129P2/OlaHsd * C57BL/6J	patent ductus arteriosus	J:67208
	postnatal lethality, complete penetrance	J:67208
Ptgs1tm1Unc/Ptgs1tm1Unc Ptgs2tm1.1Fun/Ptgs2tm1.1Fun involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6	neonatal lethality, complete penetrance	J:109548
	patent ductus arteriosus	J:109548
Ptgs1tm1Unc/Ptgs1tm1Unc Ptgs2tm1Unc/Ptgs2+ involves: 129P2/OlaHsd * C57BL/6J	delayed parturition	J:67208
Ptgs1tm1Unc/Ptgs1tm1Unc Ptgs2tm1Unc/Ptgs2tm1Unc involves: 129P2/OlaHsd * C57BL/6 * CD-1	neonatal lethality, complete penetrance	J:64073
	patent ductus arteriosus	J:64073
Ptgs1tm1Unc/Ptgs1tm1Unc Ptgs2tm1Unc/Ptgs2tm1Unc involves: 129P2/OlaHsd * C57BL/6J	cyanosis	J:67208
	neonatal lethality, incomplete penetrance	J:67208
	patent ductus arteriosus	J:67208
	postnatal lethality, complete penetrance	J:67208
	respiratory distress	J:67208
Ptgs2tm1Jed/Ptgs2+ Stk11tm1Tpm/Stk11+ involves: 129S7/SvEvBrd * C57BL/6 * CD-1	gastric polyps	J:93361
	intestine polyps	J:93361
Ptgs2tm1Jed/Ptgs2tm1Jed Stk11tm1Tpm/Stk11+ involves: 129S7/SvEvBrd * C57BL/6 * CD-1	decreased tumor incidence	J:93361
	gastric polyps	J:93361
	intestine polyps	J:93361
Ptgs2tm2(Ptgs1)Fun/Ptgs2tm2(Ptgs1)Fun involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal macrophage physiology	J:118171
	preweaning lethality, incomplete penetrance	J:118171
Ptgs2tm2.1(Ptgs1)Fun/Ptgs2tm2.1(Ptgs1)Fun involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB	abnormal fertility/fecundity	J:118171
	abnormal macrophage physiology	J:118171
	abnormal renal glomerulus morphology	J:118171
	decreased litter size	J:118171
	decreased urine prostaglandin level	J:118171
	decreased vascular permeability	J:118171
	increased blood urea nitrogen level	J:118171
	kidney inflammation	J:118171
	peritoneal inflammation	J:118171
Tg(Krt19-Ptgs2,Krt19-Ptges)8Tko/0 involves: C3H * C57BL/6	gastric metaplasia	J:116782
Tg(Krt19-Ptgs2,Krt19-Ptges)8Tko/0 Tg(Krt19-Wnt1)2Maos/0 involves: C3H * C57BL/6	abnormal stomach glandular epithelium morphology	J:116782
	decreased tumor-free survival time	J:116782
	gastric metaplasia	J:116782
	increased gastric adenocarcinoma incidence	J:116782
	increased stomach tumor incidence	J:116782, J:153058