Hmga1^tm1Mina
Targeted Allele Detail

Summary

• Symbol: Hmga1^tm1Mina
• Name: high mobility group AT-hook 1; targeted mutation 1, Mitsuyoshi Nakao
• MGI ID: MGI:4361164
• Synonyms: Hmga1-EGFP
• Gene: Hmga1 Location: Chr17:27775471-27782648 bp, + strand Genetic Position: Chr17, 14.5 cM
• Alliance: Hmga1^tm1Mina page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:153058
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• The stop codon in exon 5 was fused to an EGFP, IRES, and neo cassette. (J:153058)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hmga1 Mutation: 21 strains or lines available

References

• Original: J:153058 Akaboshi S, et al., HMGA1 is induced by Wnt/beta-catenin pathway and maintains cell proliferation in gastric cancer. Am J Pathol. 2009 Oct;175(4):1675-85
• All: 1 reference(s)