76 phenotypes from 12 alleles in 13 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gt(ROSA)26Sortm1(Actb-Met)Fmai/? Tg(Nes-cre)1Kln/? involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	normal vision/eye phenotype	J:173661
MetPar4/Met+ involves: BALB/cJ * SWR/J	decreased lung tumor incidence	J:43176
Mettm1.1Sst/Mettm1.1Sst involves: 129P2/OlaHsd * C57BL/6	abnormal liver development	J:89236
	prenatal lethality, complete penetrance	J:89236
Mettm1Cbm/Met+ involves: 129P2/OlaHsd * C57BL/6	abnormal tongue morphology	J:28570
Mettm1Cbm/Mettm1Cbm involves: 129P2/OlaHsd	abnormal placenta labyrinth morphology	J:68751
	decreased liver weight	J:68751
	decreased trophoblast giant cell number	J:68751
Mettm1Cbm/Mettm1Cbm involves: 129P2/OlaHsd * C57BL/6	abnormal diaphragm development	J:28570
	abnormal intrinsic tongue muscle morphology	J:28570
	abnormal liver parenchyma morphology	J:28570
	abnormal muscle precursor cell migration	J:28570
	abnormal myogenesis	J:28570
	abnormal placenta development	J:28570
	decreased fetal size	J:28570
	decreased tongue size	J:28570
	hypaxial muscle hypoplasia	J:28570
	lethality throughout fetal growth and development, complete penetrance	J:28570
	small liver	J:28570
Mettm1Cbm/Mettm1Cbm involves: ICR	abnormal diaphragm morphology	J:80685
	abnormal muscle precursor cell migration	J:80685
	diaphragmatic hernia	J:80685
	hypaxial muscle hypoplasia	J:80685
	thin diaphragm muscle	J:80685
Mettm1Kln/Mettm1Kln involves: 129/Sv * C57BL/6 * CD-1	abnormal fetal growth/weight/body size	J:94030
	abnormal liver development	J:94030
	abnormal myoblast migration	J:94030
	abnormal myogenesis	J:94030
	abnormal somatic motor system morphology	J:94030
	decreased liver weight	J:94030
	decreased skeletal muscle mass	J:94030
	dilated liver sinusoidal space	J:94030
	lethality throughout fetal growth and development, complete penetrance	J:94030
	small placenta	J:94030
Mettm1Sst/Mettm1Sst involves: 129P2/OlaHsd * C57BL/6	no abnormal phenotype detected	J:89236
Mettm1Sst/Mettm1Sst Sftpctm1(cre/ERT2,rtTA)Hap/Sftpc+ involves: 129 * 129P2/OlaHsd * C57BL/6 * FVB/N	abnormal pulmonary alveolus morphology	J:264185
	emphysema	J:264185
	overexpanded pulmonary alveolus	J:264185
Mettm1Sst/Mettm1Sst Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ involves: 129P2/OlaHsd * C57BL/6	abnormal hepatocyte physiology	J:89236
	abnormal response to injury	J:89236
	abnormal susceptibility to injury induced morbidity/mortality	J:89236
	impaired liver regeneration	J:89236
	impaired wound healing	J:89236
	increased hepatocyte apoptosis	J:89236
	liver failure	J:89236
	liver hemorrhage	J:89236
Mettm1Sst/Mettm1Sst Tg(mI56i-cre,EGFP)1Kc/0 involves: 129P2/OlaHsd * C57BL/6J * FVB	abnormal brain interneuron morphology	J:170554
	abnormal learning/memory/conditioning	J:170554
	abnormal orbitofrontal cortex morphology	J:170554
	abnormal primary somatosensory cortex morphology	J:170554
	abnormal striatum morphology	J:170554
	normal behavior/neurological phenotype	J:170554
	impaired cued conditioning behavior	J:170554
Mettm1Sst/Mettm1Sst Tg(Pdx1-cre)89.1Dam/0 involves: 129P2/OlaHsd * C57BL/6 * CBA	abnormal pancreatic beta cell physiology	J:196854
	abnormal pancreatic islet morphology	J:196854
	decreased circulating insulin level	J:196854
	decreased insulin secretion	J:196854
	decreased pancreatic beta cell mass	J:196854
	decreased pancreatic beta cell proliferation	J:196854
	impaired glucose tolerance	J:196854
	increased circulating glucose level	J:196854
Mettm1Sst/Mettm1Sst Tg(SFTPC-rtTA)5Jaw/0 Tg(tetO-cre)1Jaw/0 involves: 129 * 129P2/OlaHsd * C57BL/6	abnormal lung development	J:124125
	abnormal lung saccule morphology	J:124125
Mettm2Cbm/Mettm2.1Cbm Tg(Mx1-cre)1Cgn/? involves: C57BL/6 * CBA	impaired liver regeneration	J:91484
	microvesicular hepatic steatosis	J:91484
Mettm2Kln/Mettm2Kln involves: 129/Sv * C57BL/6 * CD-1	abnormal diaphragm morphology	J:94030
	abnormal fetal growth/weight/body size	J:94030
	abnormal liver development	J:94030
	abnormal motor neuron innervation pattern	J:94030
	abnormal myoblast migration	J:94030
	abnormal myogenesis	J:94030
	abnormal somatic motor system morphology	J:94030
	decreased liver weight	J:94030
	decreased skeletal muscle mass	J:94030
	dilated liver sinusoidal space	J:94030
	normal embryo phenotype	J:94030
	neonatal lethality, complete penetrance	J:94030
	respiratory failure	J:94030
Mettm3Kln/Mettm3Kln involves: 129/Sv * C57BL/6 * CD-1	no abnormal phenotype detected	J:94030
Mettm4Gvw/Met+ involves: 129 * C57BL/6J	chromosome breakage	J:94722
	glomerulonephritis	J:94722
	hydronephrosis	J:94722
	increased lymphoma incidence	J:94722
	increased sarcoma incidence	J:94722
	increased tumor incidence	J:94722
Mettm4Gvw/Met+ involves: 129 * C57BL/6J * FVB/N	increased hemangiosarcoma incidence	J:151890
	increased mammary adenocarcinoma incidence	J:151890
	increased mammary gland tumor incidence	J:151890
	increased myoepithelioma incidence	J:151890
	increased sarcoma incidence	J:151890
	increased squamous cell carcinoma incidence	J:151890
Mettm4Gvw/Mettm4Gvw involves: 129 * C57BL/6J	embryonic lethality during organogenesis, complete penetrance	J:94722
Mettm5Gvw/Met+ involves: 129 * C57BL/6J	normal mortality/aging	J:94722
	normal neoplasm	J:94722