Met^tm2.1Cbm
Targeted Allele Detail

Summary

• Symbol: Met^tm2.1Cbm
• Name: met proto-oncogene; targeted mutation 2.1, Carmen Birchmeier
• MGI ID: MGI:3050811
• Synonyms: Met^delta
• Gene: Met Location: Chr6:17463799-17573979 bp, + strand Genetic Position: Chr6, 7.83 cM, cytoband A2
• Alliance: Met^tm2.1Cbm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:91484
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Met^tm2Cbm mice crossed with Cre-deleter mice results in this allele in which exon 15 was excised. Recombination was verified by Southern blot. (J:91484)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Met Mutation: 82 strains or lines available

References

• Original: J:91484 Borowiak M, et al., Met provides essential signals for liver regeneration. Proc Natl Acad Sci U S A. 2004 Jul 20;101(29):10608-13
• All: 2 reference(s)