75 phenotypes from 3 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Itgavtm1Hyn/Itgavtm1Hyn either: (involves: 129/Sv * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6J)	abnormal blood vessel morphology	J:50951
	abnormal craniofacial development	J:50951
	abnormal embryonic growth/weight/body size	J:50951
	abnormal extraembryonic tissue morphology	J:50951
	abnormal heart morphology	J:50951
	abnormal placenta morphology	J:50951
	abnormal placenta vasculature	J:50951
	abnormal secondary palate development	J:50951
	abnormal trophoblast layer morphology	J:50951
	abnormal vitelline vasculature morphology	J:50951
	cleft secondary palate	J:50951
	decreased placental labyrinth size	J:50951
	embryonic growth retardation	J:50951
	embryonic lethality during organogenesis, incomplete penetrance	J:50951
	enlarged heart	J:50951
	hemorrhage	J:50951
	hydrocephaly	J:50951
	intestinal hemorrhage	J:50951
	intracerebral hemorrhage	J:50951
	microcephaly	J:50951
	neonatal lethality, complete penetrance	J:50951
	palatal shelves fail to meet at midline	J:50951
	pericardial edema	J:50951
	small pharyngeal arch	J:50951
	thin myocardium	J:50951
	trabecula carnea hypoplasia	J:50951
Itgavtm1Hyn/Itgavtm1Hyn involves: 129S2/SvPas * C57BL/6 * FVB/N	abnormal blood vessel morphology	J:79611
	embryonic lethality during organogenesis, incomplete penetrance	J:79611
	intracerebral hemorrhage	J:79611
	neonatal lethality, complete penetrance	J:79611
Itgavtm2.1Hyn/Itgavtm2.1Hyn involves: 129P2/OlaHsd	intracerebral hemorrhage	J:94376
Itgavtm2Hyn/Itgavtm2.1Hyn Cd19tm1(cre)Cgn/Cd19+ involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * FVB	normal digestive/alimentary phenotype	J:125508
Itgavtm2Hyn/Itgavtm2.1Hyn Lyz2tm1(cre)Ifo/Lyz2+ involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * FVB	colitis	J:125508
	impaired macrophage phagocytosis	J:125508
	increased autoantibody level	J:125508
Itgavtm2Hyn/Itgavtm2.1Hyn Tg(GFAP-cre)#Gtm/0 involves: 129P2/OlaHsd * C57BL/6 * CBA	cerebellum hemorrhage	J:94376
	intracerebral hemorrhage	J:94376
	intracranial hemorrhage	J:94376
Itgavtm2Hyn/Itgavtm2.1Hyn Tg(Nes-cre)1Kln/0 involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * FVB * SJL	abnormal brain vasculature morphology	J:94376
	abnormal embryonic/fetal subventricular zone morphology	J:94376
	abnormal gait	J:94376
	abnormal glial cell morphology	J:94376
	abnormal involuntary movement	J:94376
	abnormal motor capabilities/coordination/movement	J:94376
	abnormal posture	J:94376
	abnormal renal/urinary system physiology	J:94376
	ataxia	J:94376
	axon degeneration	J:94376
	axonal dystrophy	J:94376
	convulsive seizures	J:94376
	demyelination	J:94376
	gliosis	J:94376
	impaired coordination	J:94376
	impaired limb coordination	J:94376
	increased susceptibility to bacterial infection induced morbidity/mortality	J:94376
	intracerebral hemorrhage	J:94376
	intracranial hemorrhage	J:94376
	muscle hypertonia	J:94376
	normal muscle phenotype	J:94376
	normal nervous system phenotype	J:94376
	paraparesis	J:94376
	premature death	J:94376
	seizures	J:94376
	spinal hemorrhage	J:94376
Itgavtm2Hyn/Itgavtm2.1Hyn Tg(Tek-cre)1Ywa/0 involves: 129P2/OlaHsd * C57BL/6 * SJL	normal cardiovascular system phenotype	J:94376
Itgavtm2Hyn/Itgavtm2.1Hyn Tg(Tek-cre)1Ywa/? involves: 129S2/SvPas * C57BL/6 * FVB * SJL	abnormal dendritic cell differentiation	J:125508
	abnormal immune system morphology	J:125508
	abnormal immune system physiology	J:125508
	abnormal interferon level	J:125508
	abnormal interleukin level	J:125508
	abnormal intestinal epithelium morphology	J:125508
	abnormal leukocyte morphology	J:125508
	abnormal tumor necrosis factor level	J:125508
	colitis	J:125508
	crypts of Lieberkuhn abscesses	J:125508
	decreased regulatory T cell number	J:125508
	enlarged mesenteric lymph nodes	J:125508
	enlarged Peyer's patches	J:125508
	impaired macrophage phagocytosis	J:125508
	increased autoantibody level	J:125508
	increased inflammatory response	J:125508
	increased intestinal adenocarcinoma incidence	J:125508
	increased regulatory T cell number	J:125508
	intestinal ulcer	J:125508
	large intestinal inflammation	J:125508
	premature death	J:125508
	weight loss	J:125508