Rbpj Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rbpj
recombination signal binding protein for immunoglobulin kappa J region
MGI:96522

21 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Cd19^tm1(cre)Cgn/Cd19⁺ Rbpj^tm1Hon/Rbpj^tm1Hon Spen^tm2.1Hon/Spen^tm2.1Hon involves: 129P2/OlaHsd * C57BL/6 * CBA	decreased marginal zone B cell number	J:121523
	increased follicular B cell number	J:121523
Efnb2^tm1And/Efnb2⁺ Rbpj^tm1Kyo/Rbpj^tm1Kyo involves: 129S2/SvPas * 129S7/SvEvBrd	abnormal vascular development	J:93125
Fbxw7^tm1Kei/Fbxw7^tm1Kei Rbpj^tm1Hon/Rbpj^tm1Hon Tg(Cd4-cre)1Cwi/? involves: 129P2/OlaHsd * C57BL/6 * DBA/2	increased double-positive T cell number	J:128523
Gt(ROSA)26Sor^{tm1(Notch1)Dam}/Gt(ROSA)26Sor⁺ Rbpj^tm1Hon/Rbpj^tm1Hon Tg(Col1a1-cre)1Kry/0 involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N	normal skeleton phenotype	J:233131
Gt(ROSA)26Sor^{tm1(rtTA,EGFP)Nagy}/Gt(ROSA)26Sor⁺ Rbpj^tm1Hon/Rbpj^tm1Hon Tg(tetO-cre)1Jaw/0 involves: 129 * C57BL/6	abnormal lung development	J:155893
	neonatal lethality, complete penetrance	J:155893
Mesp1^tm2(cre)Ysa/Mesp1⁺ Rbpj^tm1Hon/Rbpj^tm1Hon Tg(CAG-cat,-Notch1)1Ysa/0 involves: 129P2/OlaHsd * C3H * C57BL/6 * CBA	abnormal heart development	J:139209
	abnormal heart morphology	J:139209
Mesp2^{tm13.1(cre/Esr1)Ysa}/Mesp2^{tm17.1(VP16/Rbpj)Ysa} involves: C57BL/6 CBA	fusion of vertebral arches	J:167045
Mesp2^{tm16.1(Rbpj)Ysa}/Mesp2^{tm16.1(Rbpj)Ysa} involves: C57BL/6 * CBA	normal embryo phenotype	J:167045
	normal skeleton phenotype	J:167045
Mesp2^{tm17.1(VP16/Rbpj)Ysa}/Mesp2⁺ involves: C57BL/6 * CBA	normal skeleton phenotype	J:167045
Mesp2^{tm17.1(VP16/Rbpj)Ysa}/Mesp2^{tm17.1(VP16/Rbpj)Ysa} involves: C57BL/6 * CBA	abnormal rostral-caudal patterning of the somites	J:167045
	abnormal vertebrae morphology	J:167045
	vertebral fusion	J:167045
Nr2f2^tm2.1Tsa/Nr2f2^tm2.1Tsa Rbpj^tm1Hon/Rbpj^tm1Hon Tg(Tek-cre)1Ywa/0 involves: 129S1/Sv * 129S7/SvEvBrd * C57BL/6 * SJL	decreased lymphatic vessel endothelial cell number	J:158959
	embryonic lethality, incomplete penetrance	J:158959
Rbpj^tm1.1Wtp/Rbpj^tm1.1Wtp involves: 129S4/SvJae * C57BL/6 * SJL * Swiss Webster	no abnormal phenotype detected	J:185868
Rbpj^tm1Hon/Rbpj^tm1.1Hon Gt(ROSA)26Sor^tm1(EYFP)Cos/Gt(ROSA)26Sor⁺ Ptf1a^{tm2(cre/ESR1)Cvw}/Ptf1a⁺ involves: 129P2/OlaHsd * 129S1/Sv * 129S6/SvEvTac	normal endocrine/exocrine gland phenotype	J:180310
Rbpj^tm1Hon/Rbpj^tm1.1Hon Gt(ROSA)26Sor^tm1(EYFP)Cos/Gt(ROSA)26Sor⁺ Hes1^{tm1(cre/ERT2)Lcm}/Hes1⁺ involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ	abnormal centroacinar cell of Langerhans morphology	J:180310
	abnormal pancreas physiology	J:180310
	normal endocrine/exocrine gland phenotype	J:180310
	increased pancreatic acinar cell number	J:180310

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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