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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Id2
inhibitor of DNA binding 2
MGI:96397
27 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Batf3tm1Kmm/Batf3tm1Kmm
Id2tm1Gtbz/Id2tm1Gtbz
B6.Cg-Batf3tm1Kmm Id2tm1Gtbz 		abnormal dendritic cell physiology J:194760
Gt(ROSA)26Sortm1(cre/ERT2)Thl/Gt(ROSA)26Sor+
Id1tm3Bene/Id1tm3Bene
Id2tm1Xdz/Id2tm1Xdz
Id3tm1Zhu/Id3tm1Zhu
involves: 129S4/SvJaeSor * C57BL/6 		premature neuronal precursor differentiation J:185426
Id1tm3Bene/Id1tm3Bene
Id2tm1Xdz/Id2+
Id3tm1Zhu/Id3tm1Zhu
Tg(Nes-cre)1Kln/0
involves: 129S4/SvJaeSor * C57BL/6 * SJL 		normal nervous system phenotype J:185426
Id1tm3Bene/Id1tm3Bene
Id2tm1Xdz/Id2tm1Xdz
Id3tm1Zhu/Id3tm1Zhu
Tg(Nes-cre)1Kln/0
involves: 129S4/SvJaeSor * C57BL/6 * SJL 		abnormal brain morphology J:185426
abnormal cell cycle J:185426
abnormal cortical ventricular zone morphology J:185426
abnormal neuron differentiation J:185426
abnormal neuronal precursor proliferation J:185426
enlarged brain ventricles J:185426
neonatal lethality, incomplete penetrance J:185426
premature neuronal precursor differentiation J:185426
thin external granule cell layer J:185426
Id2tm1Ago/Id2tm1Ago
Tg(TcraTcrb)1100Mjb/0
B6.Cg-Id2tm1Ago Tg(TcraTcrb)1100Mjb 		abnormal T cell activation J:116119
Id2tm1Gtbz/Id2tm1Gtbz
Irf8tm1Hor/Irf8tm1Hor
involves: 129P2/OlaHsd * C57BL/6 		abnormal bone marrow cell morphology/development J:194760
Id2tm1Gtbz/Id2tm1Gtbz
Nfil3tm1.1Brad/Nfil3tm1.1Brad
involves: C57BL/6 		normal hematopoietic system phenotype J:194760
normal immune system phenotype J:194760
Id2tm1Yyk/Id2+
Tg(Wnt1)1Hev/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB * SJL 		abnormal branching of the mammary ductal tree J:96305
increased mammary gland tumor incidence J:96305
mammary gland hyperplasia J:96305
Id2tm1Yyk/Id2tm1Yyk
Rorctm2Litt/Rorc+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ 		abnormal gut-associated lymphoid tissue morphology J:87395
abnormal immune system cell morphology J:87395
abnormal lymph organ development J:87395
Id2tm1Yyk/Id2tm1Yyk
Tcf3tm1Cmu/Tcf3+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ 		absent axillary lymph nodes J:125739
absent brachial lymph nodes J:125739
absent inguinal lymph nodes J:125739
decreased NK T cell number J:125739
Id2tm1Yyk/Id2tm1Yyk
Tcf3tm1Cmu/Tcf3tm1Cmu
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ 		decreased B cell number J:125739
decreased NK T cell number J:125739
normal immune system phenotype J:125739
small lymph nodes J:125739
Id2tm1Yyk/Id2tm1Yyk
Tg(Wnt1)1Hev/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB * SJL 		abnormal branching of the mammary ductal tree J:96305
increased mammary gland tumor incidence J:96305
mammary gland hyperplasia J:96305
Id2tm2.1Ago/Id2+
Id3tm2.1Cmu/Id3+
involves: C57BL/6 		normal immune system phenotype J:179006
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory