Emx1tm1(cre)Ito/Emx1+
Grin1tm1Stl/Grin1tm2Stl
involves: 129P2/OlaHsd * 129S2/SvPas * 129S4/SvJae * C57BL/6
|
abnormal postnatal growth |
J:64064
|
|
abnormal primary somatosensory cortex morphology |
J:80900
|
|
abnormal somatosensory cortex morphology |
J:64064
|
|
absent barrels in primary somatosensory cortex |
J:64064,
J:80900
|
|
decreased body weight |
J:64064
|
|
reduced NMDA receptor mediated synaptic activity in barrel cortex |
J:64064
|
Grik4tm1(cre)Mim/Grik4+
Grin1tm1Mim/Grin1tm1Mim
involves: C57BL/6N
|
abnormal brain wave pattern |
J:144994
|
|
abnormal nervous system electrophysiology |
J:144994
|
|
abnormal postural reflex |
J:144994
|
|
increased susceptibility to pharmacologically induced seizures |
J:144994
|
|
normal
nervous system phenotype |
J:144994
|
|
tonic-clonic seizures |
J:144994
|
Grin1Rgsc174/Grin1+
(D2.B6-Grin1Rgsc174 x C57BL/6J)F1
|
normal
behavior/neurological phenotype |
J:160947
|
Grin1Rgsc174/Grin1+
C57BL/6J-Grin1Rgsc174
|
abnormal behavioral response to xenobiotic |
J:160947
|
|
abnormal neuron physiology |
J:160947
|
|
abnormal physiological response to xenobiotic |
J:160947
|
|
abnormal social investigation |
J:160947
|
|
normal
behavior/neurological phenotype |
J:160947
|
|
hyperactivity |
J:160947
|
|
increased exploration in new environment |
J:160947
|
Grin1Rgsc174/Grin1+
involves: C57BL/6JJcl * DBA/2JJcl
|
hyperactivity |
J:133634
|
|
impaired passive avoidance behavior |
J:133634
|
Grin1Rgsc174/Grin1Rgsc174
C57BL/6J-Grin1Rgsc174
|
abnormal neuron physiology |
J:160947
|
|
perinatal lethality, incomplete penetrance |
J:160947
|
|
postnatal lethality, incomplete penetrance |
J:160947
|
Grin1tm1.1Ese/Grin1tm1.1Ese
involves: C57BL/6
|
abnormal glutamate-mediated receptor currents |
J:153043
|
|
abnormal miniature excitatory postsynaptic currents |
J:153043
|
|
abnormal social investigation |
J:153043
|
|
decreased prepulse inhibition |
J:153043
|
|
decreased vertical activity |
J:153043
|
|
reduced AMPA-mediated synaptic currents |
J:153043
|
|
reduced long-term potentiation |
J:153043
|
Grin1tm1.1Phs/Grin1+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
abnormal maternal grooming |
J:75497
|
|
abnormal maternal nurturing |
J:75497
|
|
abnormal nest building behavior |
J:75497
|
|
abnormal pup retrieval |
J:75497
|
|
abnormal social/conspecific interaction behavior |
J:75497
|
|
absent maternal crouching |
J:75497
|
|
hyperactivity |
J:75497
|
|
premature death |
J:75497
|
|
pup cannibalization |
J:75497
|
Grin1tm1.1Phs/Grin1tm1.1Phs
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
abnormal breathing pattern |
J:75497
|
|
abnormal nervous system electrophysiology |
J:75497
|
|
abnormal NMDA-mediated synaptic currents |
J:75497
|
|
absent gastric milk in neonates |
J:75497
|
|
aphagia |
J:75497
|
|
cyanosis |
J:75497
|
|
neonatal lethality, complete penetrance |
J:75497
|
|
normal
nervous system phenotype |
J:75497
|
|
respiratory distress |
J:75497
|
Grin1tm1.1Slab/Grin1+
involves: 129P2/OlaHsd * C57BL/6J
|
hyperactivity |
J:82670
|
|
neonatal lethality, complete penetrance |
J:82670
|
|
respiratory distress |
J:82670
|
Grin1tm1a(EUCOMM)Wtsi/Grin1+
C57BL/6N-Grin1tm1a(EUCOMM)Wtsi/Wtsi
|
thrombocytopenia |
J:175295
|
Grin1tm1Bhk/Grin1tm1Bhk
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * DBA/2
|
abnormal auditory brainstem response |
J:203256
|
|
abnormal hearing electrophysiology |
J:203256
|
|
abnormal social investigation |
J:203256
|
|
abnormal spatial working memory |
J:203256
|
|
decreased prepulse inhibition |
J:203256
|
|
decreased vocalization |
J:203256
|
|
increased grooming behavior |
J:203256
|
|
increased locomotor activity |
J:203256
|
|
increased startle reflex |
J:203256
|
|
limb grasping |
J:203256
|
|
reduced male mating frequency |
J:203256
|
Grin1tm1Bhk/Grin1tm1Bhk
involves: 129P2/OlaHsd * C57BL/6 * DBA/2
|
abnormal huddling behavior |
J:57125
|
|
abnormal motor capabilities/coordination/movement |
J:57125
|
|
abnormal social investigation |
J:57125
|
|
abnormal social/conspecific interaction behavior |
J:57125
|
|
decreased aggression towards mice |
J:91878
|
|
decreased body weight |
J:57125
|
|
decreased prepulse inhibition |
J:91878
|
|
increased locomotor activity |
J:57125
|
|
increased startle reflex |
J:91878
|
|
reduced male fertility |
J:57125
|
|
reduced male mating frequency |
J:57125
|
|
social withdrawal |
J:57125
|
|
stereotypic behavior |
J:57125
|
Grin1tm1Blt/Grin1tm1Blt
involves: 129P2/OlaHsd * C57BL/6
|
abnormal locomotor behavior |
J:62289
|
|
abnormal nervous system physiology |
J:62289
|
|
abnormal spatial learning |
J:62289
|
|
decreased susceptibility to pharmacologically induced seizures |
J:62289
|
|
impaired coordination |
J:62289
|
|
increased startle reflex |
J:62289
|
|
reduced long-term potentiation |
J:62289
|
Grin1tm1c(EUCOMM)Wtsi/Grin1tm1c(EUCOMM)Wtsi
Tg(Slc6a4-cre)ET127Gsat/0
involves: C57BL/6 * C57BL/6N * FVB/N * SJL
|
abnormal miniature excitatory postsynaptic currents |
J:193625
|
|
abnormal NMDA-mediated synaptic currents |
J:193625
|
|
decreased excitatory postsynaptic current amplitude |
J:193625
|
|
reduced NMDA-mediated synaptic currents |
J:193625
|
Grin1tm1c(EUCOMM)Wtsi/Grin1tm2.1Stl
Tg(Slc6a4-cre)ET127Gsat/0
involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL
|
abnormal miniature excitatory postsynaptic currents |
J:193625
|
|
abnormal NMDA-mediated synaptic currents |
J:193625
|
|
decreased excitatory postsynaptic current amplitude |
J:193625
|
|
reduced NMDA-mediated synaptic currents |
J:193625
|
Grin1tm1Cur/Grin1tm1.1Phs
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
abnormal breathing pattern |
J:75497
|
|
abnormal pulmonary respiratory rate |
J:75497
|
|
absence of NMDA-mediated synaptic currents |
J:75497
|
|
absent gastric milk in neonates |
J:75497
|
|
aphagia |
J:75497
|
|
cyanosis |
J:75497
|
|
neonatal lethality, complete penetrance |
J:75497
|
|
respiratory distress |
J:75497
|
Grin1tm1Cur/Grin1tm1Cur
involves: 129S1/Sv * C57BL/6
|
abnormal glutamate-mediated receptor currents |
J:66345
|
|
absence of NMDA-mediated synaptic currents |
J:66345
|
|
absent gastric milk in neonates |
J:66345
|
|
atelectasis |
J:66345
|
|
normal
cardiovascular system phenotype |
J:66345
|
|
cyanosis |
J:66345
|
|
lung hemorrhage |
J:66345
|
|
normal
nervous system phenotype |
J:66345
|
|
overexpanded pulmonary alveolus |
J:66345
|
|
perinatal lethality, complete penetrance |
J:66345
|
Grin1tm1Cur/Grin1tm2.1Phs
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
aphagia |
J:75497
|
|
neonatal lethality, complete penetrance |
J:75497
|
|
respiratory distress |
J:75497
|
Grin1tm1Jjwd/Grin1+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
|
abnormal anxiety-related response |
J:209690
|
|
abnormal behavioral response to alcohol |
J:209690
|
|
abnormal conditioned taste aversion behavior |
J:209690
|
|
abnormal NMDA-mediated synaptic currents |
J:209690
|
|
decreased alcohol consumption |
J:209690
|
|
increased alcohol consumption |
J:209690
|
|
normal
taste/olfaction phenotype |
J:209690
|
Grin1tm1Jjwd/Grin1tm1Jjwd
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
|
abnormal NMDA-mediated synaptic currents |
J:209690
|
|
postnatal lethality, complete penetrance |
J:209690
|
Grin1tm1Nak/Grin1tm1Nak
involves: 129S/Sv * C57BL/6 * DBA/2
|
abnormal glutamate-mediated receptor currents |
J:38582
|
|
abnormal suckling behavior |
J:38582
|
|
absent gastric milk in neonates |
J:38582
|
|
cyanosis |
J:38582
|
|
decreased susceptibility to neuronal excitotoxicity |
J:38582
|
|
neonatal lethality, complete penetrance |
J:38582
|
Grin1tm1Rpa/Grin1tm1.1Rpa
Not Specified
|
abnormal excitatory postsynaptic currents |
J:145468
|
|
abnormal miniature excitatory postsynaptic currents |
J:145468
|
|
impaired conditioned place preference behavior |
J:145468
|
Grin1tm1Rpa/Grin1tm1.1Rpa
Slc6a3tm1(cre)Xz/Slc6a3+
involves: 129S1/Sv
|
abnormal behavioral response to addictive substance |
J:145468
|
|
abnormal excitatory postsynaptic currents |
J:145468
|
|
abnormal miniature excitatory postsynaptic currents |
J:145468
|
|
impaired conditioned place preference behavior |
J:145468
|
|
increased miniature excitatory postsynaptic current amplitude |
J:145468
|
|
increased miniature excitatory postsynaptic current frequency |
J:145468
|
|
reduced long-term potentiation |
J:145468
|
Grin1tm1Rsp/Grin1tm1Rsp
Tg(Camk2a-tTA)1Mmay/?
Tg(tetO-cre)LC1Bjd/?
involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6
|
abnormal long-term potentiation |
J:119834
|
|
abnormal spatial working memory |
J:119834
|
Grin1tm1Rsp/Grin1tm1Rsp
Tg(Gnrh1-cre)1Rsp/0
involves: C57BL/6
|
absence of NMDA-mediated synaptic currents |
J:103818
|
|
normal
reproductive system phenotype |
J:103818
|
Grin1tm1Rsp/Grin1tm1Rsp
Tg(Slc6a3-icre)9075Gsc/0
involves: 129S1/Sv * 129X1/SvJ
|
abnormal glutamate-mediated receptor currents |
J:139693
|
|
abnormal NMDA-mediated synaptic currents |
J:139693
|
|
impaired behavioral response to cocaine |
J:139693
|
Grin1tm1Rsp/Grin1tm1Rsp
Tg(Slc6a3-icre)9075Gsc/0
involves: 129S1/Sv * 129X1/SvJ * FVB/N
|
abnormal AMPA-mediated synaptic currents |
J:139693
|
|
abnormal glutamate-mediated receptor currents |
J:139693
|
|
abnormal NMDA-mediated synaptic currents |
J:139693
|
|
impaired behavioral response to cocaine |
J:139693
|
Grin1tm1Slab/Grin1tm1Slab
involves: 129P2/OlaHsd * C57BL/6J
|
neonatal lethality, complete penetrance |
J:82670
|
Grin1tm1Stl/Grin1tm1Stl
either: (involves: 129S2/SvPas * 129/Sv) or (involves: 129S2/SvPas * BALB/c) or (involves: 129S2/SvPas * C57BL/6)
|
abnormal brainstem morphology |
J:17384
|
|
abnormal suckling behavior |
J:17384
|
|
absence of NMDA-mediated synaptic currents |
J:17384
|
|
apnea |
J:17384
|
|
ataxia |
J:17384
|
|
cyanosis |
J:17384
|
|
neonatal lethality, complete penetrance |
J:17384
|
Grin1tm1Yql/Grin1tm1Yql
Rgs9tm1.1(cre)Yql/Rgs9+
involves: 129/Sv * BALB/c * C57BL/6
|
abnormal excitatory postsynaptic currents |
J:115299
|
|
abnormal medium spiny neuron morphology |
J:115299
|
|
abnormal motor learning |
J:115299
|
|
abnormal NMDA-mediated synaptic currents |
J:115299
|
|
absent long-term depression |
J:115299
|
|
reduced long-term potentiation |
J:115299
|
Grin1tm1Yql/Grin1tm1Yql
Tg(Ppp1r2-cre)4127Nkza/0
involves: C57BL/6N
|
abnormal liquid preference |
J:156785
|
|
abnormal nervous system electrophysiology |
J:156785
|
|
abnormal nest building behavior |
J:156785
|
|
abnormal sexual interaction |
J:156785
|
|
abnormal social investigation |
J:156785
|
|
abnormal spatial working memory |
J:156785
|
|
normal
behavior/neurological phenotype |
J:156785
|
|
decreased prepulse inhibition |
J:156785
|
|
normal
growth/size/body region phenotype |
J:156785
|
|
normal
hearing/vestibular/ear phenotype |
J:156785
|
|
normal
homeostasis/metabolism phenotype |
J:156785
|
|
increased anxiety-related response |
J:156785
|
|
increased locomotor activity |
J:156785
|
|
increased thigmotaxis |
J:156785
|
|
normal
vision/eye phenotype |
J:156785
|
Grin1tm2.1Phs/Grin1+
involves: 129S1/Sv * 129X1/SvJ
|
abnormal food intake |
J:75497
|
|
abnormal motor capabilities/coordination/movement |
J:75497
|
|
decreased locomotor activity |
J:75497
|
|
impaired righting response |
J:75497
|
|
postnatal growth retardation |
J:75497
|
|
postnatal lethality, complete penetrance |
J:75497
|
Grin1tm2Blt/Grin1tm2Blt
involves: 129P2/OlaHsd * C57BL/6
|
abnormal nervous system physiology |
J:62289
|
|
absent suckling reflex |
J:62289
|
|
decreased body weight |
J:62289
|
|
postnatal growth retardation |
J:62289
|
|
postnatal lethality, complete penetrance |
J:62289
|
Grin1tm2Phs/Grin1tm2Phs
involves: 129S1/Sv * 129X1/SvJ
|
aphagia |
J:75497
|
|
decreased respiration |
J:75497
|
|
neonatal lethality, complete penetrance |
J:75497
|
Grin1tm2Slab/Grin1tm1.1Slab
involves: 129P2/OlaHsd * C57BL/6J
|
abnormal brainstem morphology |
J:82670
|
|
abnormal nervous system electrophysiology |
J:82670
|
|
abnormal trigeminal nerve morphology |
J:82670
|
|
cyanosis |
J:82670
|
|
neonatal lethality, complete penetrance |
J:82670
|
|
respiratory distress |
J:82670
|
Grin1tm2Stl/Grin1tm2Stl
involves: 129S4/SvJae * C57BL/6
|
no abnormal phenotype detected |
J:37457
|
Grin1tm2Stl/Grin1tm2Stl
Tg(Camk2a-cre)T29-1Stl/0
involves: 129S4/SvJae * BALB/c * C57BL/6
|
abnormal contextual conditioning behavior |
J:60730
|
|
abnormal excitatory postsynaptic currents |
J:37457
|
|
abnormal object recognition memory |
J:60730
|
|
abnormal olfactory discrimination memory |
J:60730
|
|
abnormal spatial learning |
J:37457
|
|
absence of NMDA-mediated synaptic currents |
J:37457
|
|
impaired social transmission of food preference |
J:60730
|
|
reduced long-term potentiation |
J:37457
|
Grin1tm2Stl/Grin1tm2Stl
Tg(Grik4-cre)G32-4Stl/0
involves: C57BL/6
|
abnormal NMDA-mediated synaptic currents |
J:77718
|
|
abnormal single cell response |
J:77718
|
|
abnormal spatial learning |
J:77718
|
|
reduced long-term potentiation |
J:77718
|
Grin1tm2Stl/Grin1tm2Stl
Tg(Pomc-cre)1Lowl/0
involves: 129S4/SvJae * C57BL/6 * FVB
|
abnormal discrimination learning |
J:122763
|
|
normal
behavior/neurological phenotype |
J:122763
|
|
impaired synaptic plasticity |
J:122763
|
|
normal
nervous system phenotype |
J:122763
|
Grin1tm2Stl/Grin1tm2Stl
Tg(Ppp1r2-cre)4127Nkza/0
involves: 129S4/SvJae * C57BL/6N
|
normal
behavior/neurological phenotype |
J:156785
|
|
normal
nervous system phenotype |
J:156785
|
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