75 phenotypes from 15 alleles in 17 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gria2em1(IMPC)H/Gria2+ C57BL/6NTac-Gria2em1(IMPC)H/H	decreased grip strength	J:211773
	increased circulating alanine transaminase level	J:211773
	prolonged QRS complex duration	J:211773
Gria2em1(IMPC)H/Gria2em1(IMPC)H C57BL/6NTac-Gria2em1(IMPC)H/H	preweaning lethality, complete penetrance	J:211773
Gria2tm1.1Bvis/Gria2tm1.1Bvis Tg(Camk2a-cre)T29-1Stl/0 129S6.Cg-Gria2tm1.1Bvis Tg(Camk2a-cre)T29-1Stl	abnormal learning/memory/conditioning	J:223717
	abnormal long-term spatial reference memory	J:223717
	enhanced long-term potentiation	J:223717
	impaired contextual conditioning behavior	J:223717
	impaired spatial learning	J:223717
Gria2tm1.1Phs/Gria2tm1.1Phs involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6	normal nervous system phenotype	J:50929
Gria2tm1Lex/Gria2tm1Lex involves: 129S5/SvEvBrd * C57BL/6	abnormal circadian sleep/wake cycle	J:82809
	decreased exploration in new environment	J:82809
	decreased grip strength	J:82809
	decreased locomotor activity	J:82809
Gria2tm1Phs/Gria2tm1Phs involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal nervous system electrophysiology	J:50929
	normal nervous system phenotype	J:50929
Gria2tm1Rlh/Gria2tm1Rlh involves: 129S1/Sv * 129X1/SvJ * C57BL/6	impaired synaptic plasticity	J:99813
Gria2tm1Rod/Gria2+ B6.129-Gria2tm1Rod/J	abnormal AMPA-mediated synaptic currents	J:104951
	increased susceptibility to neuronal excitotoxicity	J:104951
Gria2tm1Rod/Gria2tm1Rod B6.129-Gria2tm1Rod/J	abnormal AMPA-mediated synaptic currents	J:104951
	abnormal limb posture	J:104951
	abnormal response to novel object	J:104951
	decreased grip strength	J:104951
	decreased locomotor activity	J:104951
	impaired coordination	J:104951
	increased susceptibility to neuronal excitotoxicity	J:104951
Gria2tm1Rod/Gria2tm1Rod involves: 129S1/Sv * 129X1/SvJ * CD-1	abnormal reflex	J:64275
	abnormal response to novel object	J:64275
	decreased body size	J:64275
	decreased body weight	J:64275
	decreased exploration in new environment	J:64275
	decreased grooming behavior	J:64275
	enhanced long-term potentiation	J:64275
	impaired coordination	J:64275
	postnatal lethality, incomplete penetrance	J:64275
Gria2tm1Rsp/Gria2+ involves: 129S1/Sv * 129X1/SvJ	abnormal AMPA-mediated synaptic currents	J:30145
	abnormal cell physiology	J:30145
	abnormal emotion/affect behavior	J:30145
	abnormal grooming behavior	J:30145
	hippocampal neuron degeneration	J:30145
	increased locomotor activity	J:30145
	jumpy	J:30145
	paraparesis	J:30145
	postnatal growth retardation	J:30145
	postnatal lethality, complete penetrance	J:30145
	seizures	J:30145
	tonic-clonic seizures	J:30145
Gria2tm1Sans/Gria2tm1Sans involves: 129S/SvEv	normal hearing/vestibular/ear phenotype	J:98870
Gria2tm2.1Rsp/Gria2+ involves: 129S1/Sv * 129X1/SvJ	abnormal AMPA-mediated synaptic currents	J:51845
	abnormal hippocampus CA3 region morphology	J:51845
	abnormal motor capabilities/coordination/movement	J:51845
	decreased body weight	J:51845
	postnatal lethality, complete penetrance	J:51845
	seizures	J:51845
Gria2tm2Rlh/Gria2tm2Rlh involves: 129S1/Sv * 129X1/SvJ	absent long-term depression	J:107573
Gria2tm2Rsp/Gria2+ involves: 129S1/Sv * 129X1/SvJ	abnormal AMPA-mediated synaptic currents	J:51845
	premature death	J:51845
Gria2tm2Rsp/Gria2+ Tg(Camk2a-cre)1Gsc/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N	abnormal brain interneuron morphology	J:111689
	abnormal CNS glial cell morphology	J:111689
	abnormal neuron differentiation	J:111689
	loss of hippocampal neurons	J:111689
	seizures	J:111689
Gria2tm2Rsp/Gria2+ Tg(Camk2a-cre)1Gsc/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N * NMRI	abnormal olfactory discrimination memory	J:103689
Gria2tm2Rsp/Gria2+ Tg(Gria2*586N)238.2Rsp/0 involves: 129S1/Sv * 129X1/SvJ	abnormal AMPA-mediated synaptic currents	J:51845
	abnormal hippocampus CA3 region morphology	J:51845
	abnormal motor capabilities/coordination/movement	J:51845
	premature death	J:51845
	seizures	J:51845
Gria2tm2Rsp/Gria2tm2Rsp involves: 129S1/Sv * 129X1/SvJ	abnormal AMPA-mediated synaptic currents	J:51845
	abnormal excitatory postsynaptic potential	J:51845
	abnormal hippocampus CA3 region morphology	J:51845
	decreased body weight	J:51845
	lethargy	J:51845
	postnatal growth retardation	J:51845
	postnatal lethality, complete penetrance	J:51845
Gria2tm3.1Rsp/Gria2tm3.1Rsp involves: CD-1	abnormal nociception after inflammation	J:96597
	abnormal spinal cord morphology	J:96597
	abnormal touch/ nociception	J:96597
	decreased chemical nociceptive threshold	J:96597
	enhanced AMPA-mediated synaptic currents	J:96597
	hyperalgesia	J:96597
	impaired synaptic plasticity	J:96597
Gria2tm3Rsp/Gria2tm3Rsp Tg(Camk2a-cre)1Gsc/0 involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * FVB/N	abnormal AMPA-mediated synaptic currents	J:111689
	abnormal brain interneuron morphology	J:111689
	abnormal excitatory postsynaptic currents	J:111689
	abnormal excitatory postsynaptic potential	J:111689
	abnormal neuron differentiation	J:111689
	abnormal paired-pulse facilitation	J:111689
	abnormal spatial reference memory	J:111689
	abnormal spatial working memory	J:111689
	normal behavior/neurological phenotype	J:111689
	loss of hippocampal neurons	J:111689
Gria2tm3Rsp/Gria2tm3Rsp Tg(Camk2a-cre)1Gsc/0 involves: C57BL/6 * FVB/N	abnormal learning/memory/conditioning	J:103689
	abnormal olfactory discrimination memory	J:103689
	abnormal spatial learning	J:103689
	impaired coordination	J:103689
	increased anxiety-related response	J:103689
	increased exploration in new environment	J:103689
Gria2tm3Rsp/Gria2tm3Rsp Tg(Gnrh1-cre)1Rsp/0 involves: C57BL/6	abnormal AMPA-mediated synaptic currents	J:103818
	abnormal mating frequency	J:103818
	abnormal pup retrieval	J:103818
	abnormal sexual interaction	J:103818
	decreased aggression towards male mice	J:103818
	increased anxiety-related response	J:103818
	normal reproductive system phenotype	J:103818
Gria2tm3Rsp/Gria2tm3Rsp Tg(Slc6a3-icre)9075Gsc/0 involves: 129S1/Sv * 129X1/SvJ * FVB/N	abnormal glutamate-mediated receptor currents	J:139693
Tg(Gria2*586N)238.2Rsp/0 Not Specified	abnormal AMPA-mediated synaptic currents	J:51845
	abnormal amygdala morphology	J:97818
	abnormal reflex	J:97818
	abnormal spinal cord ventral horn morphology	J:97818
	abnormal ventromedial hypothalamic nucleus morphology	J:97818
	decreased body weight	J:97818
	decreased locomotor activity	J:97818
	decreased spinal cord ventral horn cell number	J:97818
	gliosis	J:97818
	increased anxiety-related response	J:97818
	motor neuron degeneration	J:51845, J:97818
	short stride length	J:97818