Gria2^tm1.1Bvis
Targeted Allele Detail

Summary

• Symbol: Gria2^tm1.1Bvis
• Name: glutamate receptor, ionotropic, AMPA2 (alpha 2); targeted mutation 1.1, B Vissel
• MGI ID: MGI:5693873
• Synonyms: fGluR2
• Gene: Gria2 Location: Chr3:80588757-80710142 bp, - strand Genetic Position: Chr3, 35.5 cM
• Alliance: Gria2^tm1.1Bvis page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:223717
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

Allele Type: Targeted (Conditional ready) Mutation: Insertion Mutation details: A loxP site was inserted upstream of exon 11. A floxed neomycin resistance cassette was inserted downstream of exon 11. Cre-mediated recombination removed the selection cassette and left exon 11 floxed. (J:223717)

Generation of the Gria2^tm1.1Bvis allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gria2 Mutation: 75 strains or lines available

References

• Original: J:223717 Wiltgen BJ, et al., A role for calcium-permeable AMPA receptors in synaptic plasticity and learning. PLoS One. 2010;5(9)
• All: 1 reference(s)