60 phenotypes from 4 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Scyl1m1Btlr/Scyl1m1Btlr C57BL/6J-Scyl1m1Btlr	ataxia	J:274649
	decreased body weight	J:274649
	impaired coordination	J:274649
Scyl1mdf/Scyl1mdf B6C3Fe a/a-Scyl1mdf/J	abnormal axon morphology	J:121817
	abnormal cerebellum morphology	J:121817
	abnormal cerebellum vermis morphology	J:121817
	abnormal innervation	J:30384
	abnormal innervation pattern to muscle	J:30384
	abnormal motor nerve collateral sprouting	J:30384
	abnormal muscle electrophysiology	J:30384
	abnormal muscle regeneration	J:30384
	abnormal myelin sheath morphology	J:30384, J:121817
	abnormal neuromuscular synapse morphology	J:30384
	abnormal optic nerve morphology	J:121817
	abnormal pelvic girdle bone morphology	J:30384
	abnormal Purkinje cell dendrite morphology	J:121817
	abnormal Purkinje cell morphology	J:121817
	abnormal stationary movement	J:30384
	abnormal tail movements	J:30384
	decreased grip strength	J:30384
	decreased Purkinje cell number	J:121817
	hindlimb paralysis	J:30384
	motor neuron degeneration	J:30384
	muscular atrophy	J:30384
	skeletal muscle fiber necrosis	J:30384
Scyl1mdf/Scyl1mdf involves: CFW * C57BL/6J * C57BR	abnormal gait	J:4479
	abnormal involuntary movement	J:4479
	abnormal locomotor behavior	J:4479
	abnormal nervous system physiology	J:4479
	abnormal peripheral nervous system regeneration	J:4479
	abnormal somatic nervous system morphology	J:28676
	decreased body size	J:4479
	decreased skeletal muscle mass	J:28676
	muscular atrophy	J:4479, J:28676
	peripheral nervous system degeneration	J:4479
	reduced fertility	J:4479
	tremors	J:4479
Scyl1tm1.1Spel/Scyl1tm1.1Spel involves: 129S6/SvEvTac	abnormal myelination	J:262629
	abnormal sciatic nerve morphology	J:262629
	decreased grip strength	J:262629
	decreased motor neuron number	J:262629
	decreased skeletal muscle fiber diameter	J:262629
	gliosis	J:262629
	motor neuron degeneration	J:262629
	paralysis	J:262629
	postnatal growth retardation	J:262629
	skeletal muscle atrophy	J:262629
Scyl1tm1.1Spel/Scyl1tm1.1Spel involves: 129S6/SvEvTac * C57BL/6J	abnormal gait	J:192445
	abnormal locomotor coordination	J:192445
	abnormal motor capabilities/coordination/movement	J:192445
	abnormal motor neuron morphology	J:192445
	abnormal pelvic girdle bone morphology	J:192445
	abnormal skeletal muscle fiber type ratio	J:192445
	astrocytosis	J:192445
	centrally nucleated skeletal muscle fibers	J:192445
	decreased body weight	J:192445
	decreased grip strength	J:192445
	decreased motor neuron number	J:192445
	demyelination	J:192445
	dystrophic muscle	J:192445
	hindlimb paralysis	J:192445
	increased variability of skeletal muscle fiber size	J:192445
	microgliosis	J:192445
	motor neuron degeneration	J:192445
	muscular atrophy	J:192445
	postnatal growth retardation	J:192445
	premature death	J:192445
	tremors	J:192445
Scyl1tm1Spel/Scyl1tm1Spel Tg(Ckmm-cre)5Khn/0 involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6J * FVB/N	normal behavior/neurological phenotype	J:192445
	normal muscle phenotype	J:192445
	normal nervous system phenotype	J:192445
Scyl1tm1Spel/Scyl1tm1Spel Tg(Nes-cre)1Kln/0 involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL	abnormal gait	J:192445
	abnormal locomotor coordination	J:192445
	abnormal motor capabilities/coordination/movement	J:192445
	astrocytosis	J:192445
	normal behavior/neurological phenotype	J:192445
	centrally nucleated skeletal muscle fibers	J:192445
	decreased body weight	J:192445
	decreased grip strength	J:192445
	decreased motor neuron number	J:192445
	decreased myocardial fiber size	J:192445
	microgliosis	J:192445
	normal muscle phenotype	J:192445
	postnatal growth retardation	J:192445
	normal skeleton phenotype	J:192445