64 phenotypes from 9 alleles in 12 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
TxnipGt(ROSA)83Sor/TxnipGt(ROSA)83Sor involves: 129S4/SvJaeSor	no abnormal phenotype detected	J:117491
TxnipHyplip1/Txnip+ involves: CAST/Ei * HcB19/Dem	increased hepatocellular carcinoma incidence	J:112292
TxnipHyplip1/TxnipHyplip1 B6.HcB19-TxnipHyplip1	abnormal lipid homeostasis	J:102224
	increased fatty acids level	J:102224
	increased liver weight	J:102224
TxnipHyplip1/TxnipHyplip1 HcB19/Dem-TxnipHyplip1	increased circulating cholesterol level	J:47109
	increased circulating triglyceride level	J:47109
	increased circulating VLDL cholesterol level	J:47109
	increased hepatocellular carcinoma incidence	J:112292
TxnipHyplip1/TxnipHyplip1 involves: CAST/Ei * HcB19/Dem	increased hepatocellular carcinoma incidence	J:112292
Txniptm1.1Rlee/Txniptm1.1Rlee involves: 129S4/SvJae	abnormal heart left ventricle morphology	J:141487
	abnormal response of heart to induced stress	J:141487
	normal cardiovascular system phenotype	J:141487
	decreased circulating glucose level	J:141487
	decreased ventricle muscle contractility	J:141487
	normal homeostasis/metabolism phenotype	J:141487
	increased cardiac muscle cell glucose uptake	J:141487
Txniptm1.1Road/Txniptm1.1Road B6.Cg-Txniptm1.1Road	abnormal cellular respiration	J:132756
	abnormal gluconeogenesis	J:132756
	abnormal glucose homeostasis	J:132756
	decreased cellular glucose uptake	J:132756
	decreased physiological sensitivity to xenobiotic	J:132756
	normal growth/size/body region phenotype	J:132756
	hypoglycemia	J:132756
	improved glucose tolerance	J:132756
	increased circulating ketone body level	J:132756
	increased circulating lactate level	J:132756
	increased circulating triglyceride level	J:132756
	increased insulin sensitivity	J:132756
	increased muscle cell glucose uptake	J:132756
	normal mortality/aging	J:132756
	normal reproductive system phenotype	J:132756
Txniptm1b(EUCOMM)Hmgu/Txniptm1b(EUCOMM)Hmgu C57BL/6N-Txniptm1b(EUCOMM)Hmgu/H	abnormal retina morphology	J:211773
	decreased bone mineral content	J:211773
	decreased bone mineral density	J:211773
	decreased circulating alkaline phosphatase level	J:211773
	increased circulating calcium level	J:211773
	increased circulating phosphate level	J:211773
	increased circulating triglyceride level	J:211773
	increased total body fat amount	J:211773
Txniptm1Jjy/Txniptm1Jjy involves: C57BL/6 * CBA	abnormal blood homeostasis	J:104563
	abnormal circulating insulin level	J:104563
	abnormal circulating phospholipid level	J:104563
	abnormal glucose homeostasis	J:104563
	abnormal lipid homeostasis	J:104563
	decreased circulating antithrombin level	J:104563
	decreased circulating glucose level	J:104563
	decreased circulating sodium level	J:104563
	hematuria	J:104563
	hepatic steatosis	J:104563
	increased bleeding time	J:104563
	increased blood urea nitrogen level	J:104563
	increased circulating cholesterol level	J:104563
	increased circulating free fatty acids level	J:104563
	increased circulating ketone body level	J:104563
	increased circulating potassium level	J:104563
	increased circulating triglyceride level	J:104563
	increased partial thromboplastin time	J:104563
	increased prothrombin time	J:104563
	increased susceptibility to induced morbidity/mortality	J:104563
	kidney failure	J:104563
	liver degeneration	J:104563
	macrovesicular hepatic steatosis	J:104563
	microvesicular hepatic steatosis	J:104563
Txniptm1Rlee/Txniptm1Rlee A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+ involves: 129S4/SvJae * FVB/N	abnormal response of heart to induced stress	J:141487
	increased cardiac muscle cell glucose uptake	J:141487
Txniptm1Road/Txniptm1Road Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ involves: C57BL/6 * DBA	normal growth/size/body region phenotype	J:132756
	normal homeostasis/metabolism phenotype	J:132756
	normal mortality/aging	J:132756
	normal reproductive system phenotype	J:132756
Txniptm1Road/Txniptm1Road Tg(Ckmm-cre)5Khn/0 involves: C57BL/6 * FVB	normal growth/size/body region phenotype	J:132756
	hypoglycemia	J:132756
	improved glucose tolerance	J:132756
	increased circulating ketone body level	J:132756
	increased circulating triglyceride level	J:132756
	normal mortality/aging	J:132756
	normal reproductive system phenotype	J:132756
Txniptm1Yu/Txniptm1Yu involves: 129	abnormal ileum morphology	J:96677
	abnormal mesenteric lymph node morphology	J:96677
	abnormal NK cell morphology	J:96677
	abnormal NK cell physiology	J:96677
	decreased CD8-positive, alpha-beta T cell number	J:96677
	decreased NK cell number	J:96677
	decreased NK T cell number	J:96677
	increased lymphocyte cell number	J:96677
	increased regulatory T cell number	J:96677
	increased T cell proliferation	J:96677