Txnip^{Gt(ROSA)83Sor}
Gene trapped Allele Detail

Summary

• Symbol: Txnip^{Gt(ROSA)83Sor}
• Name: thioredoxin interacting protein; gene trapped 83, Philippe Soriano
• MGI ID: MGI:3526865
• Synonyms: Txnip^-
• Gene: Txnip Location: Chr3:96465273-96469173 bp, + strand Genetic Position: Chr3, 41.93 cM, cytoband F2.2
• Alliance: Txnip^{Gt(ROSA)83Sor} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:117491
• Parent Cell Line: AK7 (ES Cell)
• Strain of Origin: 129S4/SvJaeSor

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: The Rosafary gene trap vector containing a SAbetaGeo pA promoter trap module and a PGKhygSD poly-A trap module was inserted into intron 8 in the reverse orientation, indicating that the trapped gene may be a novel gene anti-sense to thioredoxin interacting protein. (J:117491)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Txnip Mutation: 51 strains or lines available

References

• Original: J:117491 Schmahl J, et al., PDGF signaling specificity is mediated through multiple immediate early genes. Nat Genet. 2007 Jan;39(1):52-60
• All: 1 reference(s)