Trp53bp1 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Trp53bp1
transformation related protein 53 binding protein 1
MGI:1351320

8 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Aicda^tm1Hon/Aicda^tm1Hon Blm^tm3Brd/Blm^tm3Brd Igh^tm4.1Mnz/Igh⁺ Trp53bp1^tm1Jc/Trp53bp1^tm1Jc involves: 129S7/SvEvBrd * C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj	normal immune system phenotype	J:194603
Aicda^tm1Hon/Aicda^tm1Hon Exo1^tm1Wed/Exo1^tm1Wed Igh^tm4.1Mnz/Igh⁺ Trp53bp1^tm1Jc/Trp53bp1^tm1Jc involves: 129 * C57BL/6 * CBA/JNCrlj * SJL	abnormal immunoglobulin heavy chain V(D)J recombination	J:194603
Aicda^tm1Hon/Aicda^tm1Hon Igh^tm3Mnz/Igh^tm4.1Mnz Trp53bp1^tm1Jc/Trp53bp1^tm1Jc involves: 129 * C57BL/6 * CBA	abnormal class switch recombination	J:159173
Aicda^tm1Hon/Aicda^tm1Hon Igh^tm4.1Mnz/Igh⁺ Trp53bp1^tm1Jc/Trp53bp1^tm1Jc involves: 129 * C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj	abnormal immunoglobulin heavy chain V(D)J recombination	J:194603
Blm^tm4Ches/Blm^tm4Ches Trp53bp1^tm1Jc/Trp53bp1^tm1Jc Cd19^tm1(cre)Cgn/Cd19⁺ involves: 129P2/OlaHsd * 129S6/SvEvTac	abnormal class switch recombination	J:194603
Brca1^tm2.1Cxd/Brca1^tm2.1Cxd Trp53bp1^tm1Jc/Trp53bp1^tm1Jc involves: 129 * 129S6/SvEvTac	abnormal class switch recombination	J:307190
	chromosomal instability	J:307190
Brca1^tm2Cxd/Brca1^tm2Cxd Trp53bp1^tm1Jc/Trp53bp1^tm1Jc Cd19^tm1(cre)Cgn/Cd19⁺ involves: 129P2/OlaHsd * 129S6/SvEvTac	normal cellular phenotype	J:197442
Brca2^tm1Brn/Brca2^tm1Brn Trp53bp1^tm1Jc/Trp53bp1^tm1Jc Cd19^tm1(cre)Cgn/Cd19⁺ involves: 129P2/OlaHsd	chromosome breakage	J:197442
Helb^{tm1(KOMP)Vlcg}/Helb^{tm1(KOMP)Vlcg} Trp53bp1^tm1Jc/Trp53bp1^tm1Jc involves: 129 * C57BL/6NTac	abnormal double-strand DNA break repair	J:231089
Palb2^tm1.1Dli/Palb2^tm1.1Dli Trp53bp1^tm1Jc/Trp53bp1^tm1Jc Cd19^tm1(cre)Cgn/Cd19⁺ involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6	chromosome breakage	J:197442
Rif1^{Gt(XT0278)Wtsi}/Rif1^{Gt(XT0278)Wtsi} Trp53bp1^tm1Jc/Trp53bp1^tm1Jc involves: 129P2/OlaHsd * CD-1 * MF1	increased cellular sensitivity to ionizing radiation	J:195061

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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