79 phenotypes from 6 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gdf11tm1.1Vlcg/Gdf11tm1.1Vlcg involves: 129S6/SvEvTac * C57BL/6NTac	increased rib number	J:200671
	normal limbs/digits/tail phenotype	J:200671
Gdf11tm1.1Vlcg/Gdf11tm1.1Vlcg Tg(Nanog-cre)#Vlcg/0 involves: 129S6/SvEvTac * C57BL/6NTac	cleft palate	J:200671
	short tail	J:200671
Gdf11tm1Clf/Gdf11tm1Clf involves: 129X1/SvJ * CD-1	abnormal hindlimb bud morphology	J:81451
	abnormal kidney development	J:81451
	abnormal neuron differentiation	J:81451
	abnormal olfactory epithelium morphology	J:81451
	abnormal olfactory sensory neuron morphology	J:81451
	abnormal optic nerve morphology	J:99244
	absent amacrine cells	J:99244
	absent retina inner plexiform layer	J:99244
	absent sacral vertebrae	J:81451
	absent tail	J:81451
	decreased caudal vertebrae number	J:81451
	decreased retina photoreceptor cell number	J:99244
	delayed optic fissure closure	J:99244
	increased neuronal precursor cell number	J:99244
	increased retina ganglion cell number	J:99244
	neonatal lethality, complete penetrance	J:81451
	vertebral transformation	J:81451
Gdf11tm1Sjl/Gdf11+ involves: 129S1/Sv * 129X1/SvJ	abnormal axial skeleton morphology	J:55879
	abnormal cervical vertebrae morphology	J:55879
	abnormal kidney development	J:83365
	absent ureter	J:83365
	asymmetric rib joints	J:55879
	increased rib number	J:55879
	lumbar vertebral transformation	J:55879
	single kidney	J:83365
	thoracic vertebral transformation	J:55879
Gdf11tm1Sjl/Gdf11+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal sternocostal joint morphology	J:201148
	cleft palate	J:201148
	normal homeostasis/metabolism phenotype	J:94455
	increased pancreatic alpha cell mass	J:94455
	increased pancreatic islet number	J:94455
	increased rib number	J:201148
	small pancreatic islets	J:94455
Gdf11tm1Sjl/Gdf11tm1Sjl involves: 129S1/Sv * 129X1/SvJ	abnormal anus morphology	J:136243
	abnormal axial skeleton morphology	J:55879
	abnormal caudal vertebrae morphology	J:158173
	abnormal hindlimb morphology	J:55879
	abnormal kidney development	J:55879, J:83365
	abnormal metanephros morphology	J:83365
	abnormal palate morphology	J:55879, J:136243
	abnormal rectum morphology	J:136243
	abnormal rib morphology	J:55879
	abnormal rostral-caudal axis patterning	J:55879
	abnormal sacral vertebrae morphology	J:55879
	abnormal spinal cord morphology	J:136243
	abnormal vertebrae morphology	J:55879
	abnormal vertebral column morphology	J:136243
	absent kidney	J:83365, J:136243
	absent tail	J:136243
	absent ureter	J:83365
	absent ureteric bud	J:83365
	asymmetric rib joints	J:55879
	normal cardiovascular system phenotype	J:136243
	caudal body truncation	J:158173
	cervical vertebral transformation	J:55879
	decreased caudal vertebrae number	J:55879, J:158173
	decreased nephron number	J:83365
	impaired branching involved in ureteric bud morphogenesis	J:83365
	increased apoptosis	J:83365
	increased lumbar vertebrae number	J:158173
	increased presacral vertebrae number	J:55879
	increased rib number	J:55879, J:136243
	increased thoracic vertebrae number	J:136243, J:158173
	normal limbs/digits/tail phenotype	J:136243, J:158173
	lumbar vertebral transformation	J:55879
	neonatal lethality	J:158173
	neonatal lethality, complete penetrance	J:55879
	omphalocele	J:136243
	normal respiratory system phenotype	J:136243
	short tail	J:55879
	single kidney	J:83365
	small kidney	J:83365
	thoracic vertebral transformation	J:55879
	vertebral transformation	J:55879
Gdf11tm1Sjl/Gdf11tm1Sjl involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal embryonic epiblast morphology	J:272567
	abnormal tail morphology	J:272567
	abnormal tailgut morphology	J:272567
	bifurcated tail	J:272567
	increased spinal cord size	J:272567
Gdf11tm1Sjl/Gdf11tm1Sjl involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal axial skeleton morphology	J:201148
	abnormal exocrine pancreas morphology	J:94455
	abnormal pancreas morphology	J:94455
	abnormal pancreatic beta cell differentiation	J:94455
	abnormal spleen morphology	J:94455
	abnormal sternocostal joint morphology	J:201148
	abnormal stomach epithelium morphology	J:94455
	abnormal stomach morphology	J:94455
	decreased pancreatic acinar cell number	J:94455
	decreased pancreatic beta cell mass	J:94455
	increased pancreatic alpha cell mass	J:94455
	increased rib number	J:201148
	pancreatic islet hyperplasia	J:94455
	small pancreatic islets	J:94455
Gdf11tm1Sjl/Gdf11tm2.1Sjl Tg(Myl1-cre)1Sjl/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6N * FVB * SJL/J	normal muscle phenotype	J:158173
Gdf11tm2.2Sjl/Gdf11+ involves: C57BL/6 * CBA * FVB	increased thoracic vertebrae number	J:158173
Gdf11tm2.2Sjl/Gdf11tm2.2Sjl involves: C57BL/6 * CBA * FVB	increased thoracic vertebrae number	J:158173
Gdf11tm2b(EUCOMM)Hmgu/Gdf11+ C57BL/6N-Gdf11tm2b(EUCOMM)Hmgu/Bay	increased cardiac stroke volume	J:211773
Gdf11tm2b(EUCOMM)Hmgu/Gdf11tm2b(EUCOMM)Hmgu C57BL/6N-Gdf11tm2b(EUCOMM)Hmgu/Bay	abnormal craniofacial morphology	J:211773
	abnormal facial morphology	J:211773
	abnormal tail morphology	J:211773
	cleft palate	J:211773
	preweaning lethality, complete penetrance	J:211773