Prkag2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Prkag2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
MGI:1336153

20 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Prkag2^em1(IMPC)J/Prkag2^em1(IMPC)J C57BL/6NJ-Prkag2^em1(IMPC)J/Mmjax	decreased exploration in new environment	J:211773
	decreased thigmotaxis	J:211773
Prkag2^tm1.1Geno/Prkag2^tm1.1Geno B6J.129S(Cg)-Prkag2^tm1.1Geno	abnormal inflammatory response	J:235379
	abnormal pancreatic beta cell physiology	J:235379
	abnormal sinoatrial node conduction	J:256296
	abnormal sinoatrial node morphology	J:256296
	decreased cardiac muscle contractility	J:256296
	decreased circulating insulin level	J:235379
	decreased heart rate	J:256296
	hepatic steatosis	J:235379
	impaired glucose tolerance	J:235379
	increased body fat mass	J:235379
	increased cardiac muscle glycogen level	J:256296
	increased susceptibility to age related obesity	J:235379
	increased white fat cell size	J:235379
	insulin resistance	J:235379
	polyphagia	J:235379
	sinus bradycardia	J:256296
	white adipose tissue inflammation	J:235379
Prkag2^tm1.1Geno/Prkag2^tm1.1Geno Edil3^{Tg(Sox2-cre)1Amc}/Edil3⁺ B6.Cg-Prkag2^tm1.1Geno Edil3^{Tg(Sox2-cre)1Amc}	abnormal sinoatrial node conduction	J:256296
	increased heart rate	J:256296

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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