62 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Casp8em1Hbz/Casp8em1Hbz Mlklem1Hbz/Mlklem1Hbz involves: C57BL/6	decreased B cell number	J:342732
	decreased leukocyte cell number	J:342732
	decreased lymphocyte cell number	J:342732
	decreased mature B cell number	J:342732
	decreased T cell number	J:342732
	enlarged spleen	J:342732
	increased CD11b-high dendritic cell number	J:342732
	increased granulocyte number	J:342732
	increased macrophage cell number	J:342732
Casp8em1Hbz/Casp8em1Hbz Ripk1em1Hbz/Ripk1em1Hbz Ripk3tm1Xidw/Ripk3tm1Xidw involves: 129S1/Sv * 129X1/SvJ * C57BL/6	decreased leukocyte cell number	J:342732
	decreased lymphocyte cell number	J:342732
	decreased mature B cell number	J:342732
	decreased T cell number	J:342732
Casp8em1Hbz/Casp8em1Hbz Ripk1em4Hbz/Ripk1em4Hbz Ripk3tm1Xidw/Ripk3tm1Xidw involves: 129S1/Sv * 129X1/SvJ * C57BL/6	decreased body size	J:342732
	preweaning lethality, complete penetrance	J:342732
	scaly skin	J:342732
	skin lesions	J:342732
Casp8em1Hbz/Casp8em1Hbz Ripk3tm1Xidw/Ripk3tm1Xidw involves: 129S1/Sv * 129X1/SvJ * C57BL/6	decreased B cell number	J:342732
	decreased leukocyte cell number	J:342732
	decreased lymphocyte cell number	J:342732
	decreased mature B cell number	J:342732
	decreased T cell number	J:342732
	enlarged spleen	J:342732
	increased CD11b-high dendritic cell number	J:342732
	increased granulocyte number	J:342732
	increased macrophage cell number	J:342732
Casp8tm1.1Raz/Casp8tm1.1Raz Otulinem1Gvl/Otulinem1Gvl Ripk3tm1Vmd/Ripk3tm1Vmd involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J	normal embryo phenotype	J:312394
	enlarged lymph nodes	J:312394
	normal immune system phenotype	J:312394
	normal integument phenotype	J:312394
Casp8tm1.1Raz/Casp8tm1.1Raz Ripk3tm1Vmd/Ripk3+ involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ	abnormal visceral yolk sac blood island morphology	J:170815
	abnormal vitelline vasculature morphology	J:170815
	embryonic growth arrest	J:170815
	embryonic lethality, complete penetrance	J:170815
Casp8tm1.1Raz/Casp8tm1.1Raz Ripk3tm1Vmd/Ripk3tm1Vmd involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ	abnormal liver physiology	J:170815
	abnormal macrophage physiology	J:170815
	decreased hepatocyte apoptosis	J:170814
	decreased macrophage apoptosis	J:170815
	decreased thymocyte apoptosis	J:170814
	enlarged axillary lymph nodes	J:170815
	enlarged cervical lymph nodes	J:170815
	enlarged lymph nodes	J:170814
	enlarged spleen	J:170814, J:170815
	enlarged thymus	J:170814
	normal growth/size/body region phenotype	J:170814
	normal hematopoietic system phenotype	J:170814, J:170815
	normal immune system phenotype	J:170815
	increased B cell number	J:170815
	increased inflammatory response	J:170815
	increased leukocyte cell number	J:170815
	increased spleen white pulp amount	J:170815
	increased T cell number	J:170814, J:170815
	large lymphoid organs	J:170814
	lymph node hyperplasia	J:170815
	normal mortality/aging	J:170814, J:170815
Casp8tm1.1Vmd/Casp8+ Ripk3tm2Vmd/Ripk3tm2Vmd involves: C57BL/6N	lethality throughout fetal growth and development, complete penetrance	J:209137
Casp8tm1.1Vmd/Casp8tm1.1Vmd Ripk3tm2Vmd/Ripk3tm2Vmd involves: C57BL/6N	enlarged lymph nodes	J:209137
	enlarged spleen	J:209137
	increased T cell number	J:209137
	normal mortality/aging	J:209137
Casp8tm1Clie/Casp8tm1Clie Ikbkgtm1.1Chtr/Ikbkgtm1.1Chtr Tg(Alb1-cre)7Gsc/0 involves: 129P2/OlaHsd * C57BL/6 * FVB/N	abnormal biliary tract morphology	J:218665
	abnormal circulating enzyme level	J:218665
	abnormal liver morphology	J:218665
	decreased body size	J:218665
	enlarged liver	J:218665
	hepatic necrosis	J:218665
	increased bile salt level	J:218665
	increased circulating alkaline phosphatase level	J:218665
	increased circulating bilirubin level	J:218665
	intrahepatic cholestasis	J:218665
	liver fibrosis	J:218665
	normal neoplasm	J:218665
Casp8tm1Clie/Casp8tm1Clie Map3k7tm1Aki/Map3k7tm1Aki Tg(Alb1-cre)7Gsc/0 involves: 129P2/OlaHsd * FVB/N	abnormal bile duct morphology	J:160521
	abnormal liver morphology	J:160521
	bile duct proliferation	J:160521
	focal hepatic necrosis	J:160521
	increased circulating alanine transaminase level	J:160521
	increased circulating aspartate transaminase level	J:160521
	increased circulating bilirubin level	J:160521
	normal mortality/aging	J:160521
	postnatal growth retardation	J:160521
Casp8tm1Syon/Casp8tm1Syon Tg(Myh7-BVp35-EGFP)#Ksa/? involves: 129S1/Sv * 129X1/SvJ * C3H * C57BL/6	abnormal neural tube morphology	J:102279
	abnormal vitelline vasculature morphology	J:102279
	normal cardiovascular system phenotype	J:102279
	embryonic lethality during organogenesis, complete penetrance	J:102279
	hemopericardium	J:102279
	increased cardiomyocyte apoptosis	J:102279