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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Fadd
Fas associated via death domain
MGI:109324
50 phenotypes from 7 alleles in 9 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Faddtm1.1Mpa/Faddtm1.1Mpa
involves: BALB/cJ * C57BL/6 * SJL
embryonic lethality J:167475
Faddtm1e.1(KOMP)Wtsi/Fadd+
C57BL/6N-Faddtm1e.1(KOMP)Wtsi/Ucd
abnormal uterus morphology J:211773
decreased lean body mass J:211773
increased total body fat amount J:211773
Faddtm1e.1(KOMP)Wtsi/Faddtm1e.1(KOMP)Wtsi
C57BL/6N-Faddtm1e.1(KOMP)Wtsi/Ucd
abnormal embryo size J:211773
abnormal neural tube closure J:211773
preweaning lethality, complete penetrance J:211773
Faddtm1Mak/Faddtm1Mak
either: (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * CD-1)
abnormal myocardium layer morphology J:46527
decreased embryo size J:46527
decreased fibroblast apoptosis J:46527
embryonic growth retardation J:46527
embryonic lethality during organogenesis, complete penetrance J:46527
internal hemorrhage J:46527
thin myocardium J:46527
trabecula carnea hypoplasia J:46527
Faddtm1Mpa/Faddtm1Mpa
Mogtm1(cre)Gkl/Mog+
involves: C57BL/6 * SJL
abnormal oligodendrocyte apoptosis J:167475
decreased susceptibility to experimental autoimmune encephalomyelitis J:167475
normal immune system phenotype J:167475
normal nervous system phenotype J:167475
Faddtm1Mpa/Faddtm1Mpa
Tg(Vil1-cre)997Gum/0
B6.Cg-Faddtm1Mpa Tg(Vil1-cre)997Gum
abnormal cecum morphology J:175865
abnormal colon morphology J:175865
abnormal enterocyte physiology J:175865
abnormal enterocyte proliferation J:175865
abnormal intestinal mucosa morphology J:175865
cecum inflammation J:175865
colitis J:175865
crypts of Lieberkuhn abscesses J:175865
decreased body weight J:175865
decreased Paneth cell number J:175865
diarrhea J:175865
increased enterocyte apoptosis J:175865
intestinal ulcer J:175865
postnatal lethality, incomplete penetrance J:175865
Faddtm1Wnt/Faddtm1Wnt
involves: 129S4/SvJae
decreased sensitivity to induced cell death J:63946
embryonic lethality, complete penetrance J:46526
Faddtm1Wnt/Faddtm1Wnt
Tg(Fadd/EGFP)#Jizh/?
Tg(Cd4-cre)1Cwi/?
involves: 129S4/SvJae * C57BL/6 * DBA/2
decreased activated T cell number J:113207
decreased sensitivity to induced cell death J:113207
decreased single-positive T cell number J:113207
normal immune system phenotype J:113207
increased B cell number J:113207
Faddtm1Wnt/Faddtm1Wnt
Tg(Fadd/EGFP)#Jizh/?
Tg(Lck-cre)1Cwi/?
involves: 129S4/SvJae
decreased activated T cell number J:113207
decreased sensitivity to induced cell death J:113207
decreased single-positive T cell number J:113207
normal immune system phenotype J:113207
increased B cell number J:113207
Faddtm1Wnt/Faddtm1Wnt
Tg(Fadd/EGFP)#Jizh/?
Tg(Mx1-cre)1Cgn/?
involves: 129S4/SvJae * C57BL/6 * CBA
abnormal bone marrow cell morphology/development J:168722
abnormal erythrocyte morphology J:168722
decreased bone marrow cell number J:168722
spleen hypoplasia J:168722
thymus hypoplasia J:168722
Faddtm2.1Wnt/Faddtm2.1Wnt
Tg(Cd4-cre)1Cwi/?
B6.Cg-Tg(Cd4-cre)1Cwi Faddtm2.1Wnt
abnormal erythrocyte cell number J:162312
abnormal T cell proliferation J:162312
abnormal T cell subpopulation ratio J:162312
abnormal thymocyte apoptosis J:162312
enlarged lymph nodes J:162312
enlarged spleen J:162312
increased B cell number J:162312
increased susceptibility to parasitic infection J:162312

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory