67 phenotypes from 6 alleles in 9 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Srftm1Nor/Srftm1Nor involves: 129P2/OlaHsd	abnormal gastrulation	J:50876
	absent mesoderm	J:50876
	decreased embryo size	J:50876
	embryonic growth retardation	J:50876
	embryonic lethality during organogenesis, complete penetrance	J:50876
	failure of primitive streak formation	J:50876
Srftm1Rjs/Srftm1Rjs involves: 129S7/SvEvBrd * C57BL/6	abnormal gastrulation	J:101311
	embryonic lethality, complete penetrance	J:101311
Srftm1Rjs/Srftm2.1Nor Tg(Myh6-cre)2182Mds/0 involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * FVB/N	abnormal fetal atrioventricular canal morphology	J:101311
	abnormal heart ventricle morphology	J:101311
	abnormal interventricular groove morphology	J:101311
	abnormal interventricular septum morphology	J:101311
	abnormal myocardium layer morphology	J:101311
	abnormal pericardium morphology	J:101311
	distended pericardium	J:101311
	embryonic growth arrest	J:101311
	embryonic lethality during organogenesis, complete penetrance	J:101311
	increased cardiomyocyte apoptosis	J:101311
	irregular heartbeat	J:101311
	pericardial effusion	J:101311
Srftm1Rmn/Srftm1Rmn H2az2Tg(Wnt1-cre)11Rth/H2az2+ involves: 129S6/SvEvTac * C57BL/6J * CBA/J	absent thyroid gland	J:144862
	athymia	J:144862
	normal craniofacial phenotype	J:144862
	embryonic lethality, complete penetrance	J:144862
	normal hearing/vestibular/ear phenotype	J:144862
	mandible hypoplasia	J:144862
	persistent truncus arteriosus	J:144862
	ventricular septal defect	J:144862
Srftm1Rmn/Srftm1Rmn Tg(Tagln-cre)1Jomm/0 involves: CD-1	abnormal myocardial fiber morphology	J:94725
	embryonic lethality during organogenesis, complete penetrance	J:94725
	vascular smooth muscle hypotrophy	J:94725
Srftm1Zli/Srftm1Zli involves: 129/Sv * C57BL/6	no abnormal phenotype detected	J:91025
Srftm1Zli/Srftm1Zli A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+ involves: 129 * C57BL/6J * FVB/N	abnormal cardiac muscle relaxation	J:135043
	abnormal intercalated disk morphology	J:135043
	abnormal myocardial fiber morphology	J:135043
	abnormal myocardium layer morphology	J:135043
	abnormal Z line morphology	J:135043
	cardiac fibrosis	J:135043
	cardiac hypertrophy	J:135043
	congestive heart failure	J:135043
	decreased ventricle muscle contractility	J:135043
	dilated cardiomyopathy	J:135043
	dilated heart ventricle	J:135043
	increased heart left ventricle size	J:135043
	premature death	J:135043
Srftm1Zli/Srftm1Zli Tg(Myh7-cre)1Zli/0 involves: 129/Sv * C57BL/6	abnormal apoptosis	J:91025
	abnormal heart shape	J:91025
	abnormal myocardial fiber morphology	J:91025
	disorganized myocardium	J:91025
	embryonic growth retardation	J:91025
	embryonic lethality, complete penetrance	J:91025
	internal hemorrhage	J:91025
	thin interventricular septum	J:91025
	thin myocardium	J:91025
	trabecula carnea hypoplasia	J:91025
Srftm2.1Nor/Srftm2.1Nor Tg(Ckmm-cre)5Khn/0 involves: 129P2/OlaHsd * C57BL/6	abnormal skeletal muscle fiber morphology	J:96122
	lethargy	J:96122
	postnatal growth retardation	J:96122
	postnatal lethality, complete penetrance	J:96122
Srftm2.1Nor/Srftm2.1Nor Tg(Myog-cre)1Eno/0 involves: 129P2/OlaHsd * C57BL/6	abnormal diaphragm morphology	J:96122
	abnormal skeletal muscle fiber morphology	J:96122
	normal cardiovascular system phenotype	J:96122
	cyanosis	J:96122
	decreased birth weight	J:96122
	decreased skeletal muscle mass	J:96122
	kyphosis	J:96122
	neonatal lethality, complete penetrance	J:96122
	no spontaneous movement	J:96122
	respiratory failure	J:96122
Srftm2Nor/Srftm2Nor involves: 129P2/OlaHsd	no abnormal phenotype detected	J:75123
Srftm2Nor/Srftm2Nor Cd19tm1(cre)Cgn/Cd19+ involves: 129P2/OlaHsd	abnormal mature B cell morphology	J:124767
	absent marginal zone B cells	J:124767
	decreased B cell number	J:124767
	decreased B-1 B cell number	J:124767
Srftm2Nor/Srftm2Nor Tg(Cd4-cre)1Cwi/? involves: 129P2/OlaHsd * C57BL/6 * DBA/2	decreased CD4-positive, alpha-beta T cell number	J:124767
	decreased CD8-positive, alpha-beta T cell number	J:124767
	decreased T cell number	J:124767
	decreased thymocyte number	J:124767