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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Atoh1
atonal bHLH transcription factor 1
MGI:104654
30 phenotypes from 7 alleles in 7 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Atoh1tm1(cre)Gan/Atoh1tm1(cre)Gan
involves: 129S6/SvEvTac * C57BL/6
neonatal lethality, complete penetrance J:160667
Atoh1tm1(cre/ERT2)Mhos/Atoh1tm1(cre/ERT2)Mhos
Not Specified
abnormal cochlear VIII nucleus morphology J:149533
abnormal glutaminergic neuron morphology J:149533
Atoh1tm1Hzo/Atoh1tm1Hzo
involves: 129S7/SvEvBrd
abnormal cerebellar Purkinje cell layer J:44241
abnormal cerebellum external granule cell layer morphology J:44241
absent cerebellar foliation J:44241
cyanosis J:44241
neonatal lethality, complete penetrance J:44241
respiratory failure J:44241
small cerebellum J:44241
Atoh1tm2Hzo/Atoh1tm2Hzo
Not Specified
abnormal cerebellar Purkinje cell layer J:60393
abnormal cerebellum external granule cell layer morphology J:60393
abnormal hindbrain development J:105186
absent cerebellar foliation J:60393
absent cochlear hair cells J:55694
absent vestibular hair cells J:55694
cyanosis J:60393
decreased pulmonary respiratory rate J:155760
neonatal lethality, complete penetrance J:60393, J:155760
normal nervous system phenotype J:60393
respiratory failure J:60393
small cerebellum J:60393
Atoh1tm2Hzo/Atoh1tm3.1Hzo
involves: 129S7/SvEvBrd * C57BL/6J * FVB/N * SJL
neonatal lethality, complete penetrance J:128312
Atoh1tm2Hzo/Atoh1tm3Hzo
Tg(Fabp1-cre)1Jig/0
involves: 129S7/SvEvBrd * C57BL/6J * FVB/N * SJL
abnormal small intestine crypts of Lieberkuhn morphology J:128312
impaired intestine regeneration J:128312
normal mortality/aging J:128312
Atoh1tm2Hzo/Atoh1tm3Hzo
Tg(Vil1-cre)997Gum/0
involves: 129S7/SvEvBrd * C57BL/6J * SJL
postnatal lethality, complete penetrance J:128312
Atoh1tm3Hzo/Atoh1tm1Hzo
Gt(ROSA)26Sortm1(cre/ERT)Nat/Gt(ROSA)26Sor+
involves: 129 * 129S7/SvEvBrd
thin external granule cell layer J:155047
Atoh1tm3Hzo/Atoh1tm3Hzo
involves: 129S7/SvEvBrd
decreased neuronal precursor proliferation J:155047
Atoh1trhl/Atoh1trhl
B6.Cg-Atoh1trhl
abnormal cerebellum external granule cell layer morphology J:209662
abnormal distortion product otoacoustic emission J:209662
abnormal gait J:209662
abnormal pinna reflex J:209662
absent cerebellar foliation J:209662
cochlear inner hair cell degeneration J:209662
cochlear outer hair cell degeneration J:209662
deafness J:209662
decreased inner hair cell stereocilia number J:209662
decreased outer hair cell stereocilia number J:209662
impaired hearing J:209662
increased or absent threshold for auditory brainstem response J:209662
normal mortality/aging J:209662
small cerebellum J:209662

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory