92 phenotypes from 15 alleles in 23 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Stat1fae/Stat1fae C57BL/6JSfdAnu-Stat1fae/Anu	abnormal T cell activation	J:105311
	abnormal T-helper 2 physiology	J:105311
	increased IgG level	J:105311
Stat1m1Anu/Stat1m1Anu C57BL/6JSfdAnu-Stat1m1Anu	abnormal response to infection	J:104190
Stat1m1Btlr/Stat1m1Btlr C57BL/6J-Stat1m1Btlr	abnormal macrophage physiology	J:105543
	increased susceptibility to Herpesvirales infection	J:105543
	increased susceptibility to Riboviria infection	J:105543
Stat1m2Btlr/Stat1m2Btlr C57BL/6J-Stat1m2Btlr	decreased interferon-gamma secretion	J:134096
	decreased NK cell degranulation	J:134096
	impaired natural killer cell mediated cytotoxicity	J:134096
	increased susceptibility to Herpesvirales infection	J:134096
Stat1m3Btlr/Stat1m3Btlr C57BL/6J-Stat1m3Btlr	impaired natural killer cell mediated cytotoxicity	J:254835
Stat1m4Btlr/Stat1m4Btlr C57BL/6J-Stat1m4Btlr	abnormal CD8-positive, naive alpha-beta T cell number	J:264800
	decreased B cell number	J:264800
	decreased B-1 B cell number	J:264800
	decreased CD8-positive, alpha-beta T cell number	J:264800
	decreased NK cell number	J:264800
	decreased single-positive T cell number	J:264800
	increased CD4-positive, alpha-beta T cell number	J:264800
	increased effector memory CD8-positive, alpha-beta T cell number	J:264800
	increased NK T cell number	J:264800
Stat1m5Btlr/Stat1m5Btlr C57BL/6J-Stat1m5Btlr	abnormal CD4-positive T cell differentiation	J:274938
	abnormal CD8-positive, alpha-beta T cell differentiation	J:274938
	abnormal T cell differentiation	J:274938
	decreased CD8-positive, naive alpha-beta T cell number	J:274938
	decreased cytotoxic T cell cytolysis	J:274938
	increased CD4-positive, alpha-beta T cell number	J:274938
	increased effector memory CD4-positive, alpha-beta T cell number	J:274938
	increased effector memory CD8-positive, alpha-beta T cell number	J:274938
	increased T cell number	J:274938
Stat1tm1.2Mmul/Stat1tm1.2Mmul B6.129P2-Stat1tm1.2Mmul	no abnormal phenotype detected	J:183580
Stat1tm1Dlv/Stat1tm1Dlv B6.129-Stat1tm1Dlv	increased susceptibility to Herpesvirales infection	J:81243
	increased susceptibility to Togaviridae infection	J:81243
Stat1tm1Dlv/Stat1tm1Dlv B6.129S-Stat1tm1Dlv	abnormal NK cell physiology	J:79552
	impaired natural killer cell mediated cytotoxicity	J:79552
	increased circulating interferon-gamma level	J:79552
	increased circulating interleukin-12b level	J:79552
	increased mammary adenocarcinoma incidence	J:216040
Stat1tm1Dlv/Stat1tm1Dlv either: (involves: 129S/SvEv * C57BL/6) or (involves: 129S/SvEv * C57BL/6 * CD-1)	abnormal intestine morphology	J:31325
	abnormal leukocyte physiology	J:31325
	decreased body size	J:31325
	increased susceptibility to Coronaviridae infection	J:31325
	increased susceptibility to Riboviria infection	J:31325
	lethality at weaning, complete penetrance	J:31325
	multifocal hepatic necrosis	J:31325
Stat1tm1Dlv/Stat1tm1Dlv involves: 129S/SvEv	abnormal MHC II cell surface expression on macrophages	J:130622
	decreased level of surface class I molecules	J:130622
	decreased susceptibility to endotoxin shock	J:130622
	normal immune system phenotype	J:99728
	increased circulating interferon-gamma level	J:130622
	increased susceptibility to bacterial infection	J:130622
	increased susceptibility to Riboviria infection	J:130622
	normal vision/eye phenotype	J:88422
Stat1tm1Mam/Stat1tm1Mam Tg(MMTV-cre)#Mam/0 involves: 129S/SvEv * FVB	normal integument phenotype	J:169262
Stat1tm1Mam/Stat1tm1Mam Tg(Wap-cre)11738Mam/0 involves: 129S/SvEv * C57BL/6 * SJL	normal integument phenotype	J:169262
Stat1tm1Rds/Stat1tm1Rds 129S6/SvEv-Stat1tm1Rds/Tac	abnormal macrophage physiology	J:136368
	abnormal nitric oxide homeostasis	J:122801
	abnormal osteoclast differentiation	J:131353
	abnormal redox activity	J:122801
	bronchiolitis	J:286237
	decreased circulating interferon-gamma level	J:122801
	decreased hepatocyte apoptosis	J:122801
	decreased interleukin-1 beta secretion	J:136368
	decreased susceptibility to neuronal excitotoxicity	J:116659
	increased cardiomyocyte apoptosis	J:120449
	increased mammary adenocarcinoma incidence	J:216040
	increased myocardial infarct size	J:120449
	increased NK T cell number	J:122801
	increased susceptibility to Coronaviridae infection	J:286237
	increased susceptibility to Coronaviridae infection induced morbidity/mortality	J:286237
	lung inflammation	J:286237
	peritoneal inflammation	J:286237
	pleuritis	J:286237
	pulmonary edema	J:286237
	pulmonary necrosis	J:286237
Stat1tm1Rds/Stat1tm1Rds B6.129-Stat1tm1Rds	abnormal osteoblast differentiation	J:84894
	abnormal tibia morphology	J:84894
	increased bone mass	J:84894
	increased bone resorption	J:84894
	increased compact bone thickness	J:84894
	increased compact bone volume	J:84894
	increased osteoclast cell number	J:84894
	increased trabecular bone volume	J:84894
Stat1tm1Rds/Stat1tm1Rds C3.129-Stat1tm1Rds	tumor regression	J:108303
Stat1tm1Rds/Stat1tm1Rds either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6)	abnormal cell physiology	J:31326
	increased susceptibility to bacterial infection	J:31326
	increased susceptibility to Riboviria infection	J:31326
Stat1tm1Rds/Stat1tm1Rds involves: 129	abnormal cell cycle	J:109408
	abnormal common myeloid progenitor cell morphology	J:109408
	abnormal cornea morphology	J:62316
	decreased sensitivity to induced cell death	J:62316
	increased susceptibility to Herpesvirales infection	J:81243
	increased susceptibility to Riboviria infection	J:66564
	increased susceptibility to Togaviridae infection	J:81243
Stat1tm1Tdec/Stat1tm1Tdec involves: 129P2/OlaHsd * BALB/c	abnormal macrophage physiology	J:130622
	abnormal MHC II cell surface expression on macrophages	J:130622
	decreased susceptibility to endotoxin shock	J:130622
	increased susceptibility to bacterial infection	J:130622
	increased susceptibility to Riboviria infection	J:130622
Stat1tm1Uvin/Stat1tm1Uvin involves: 129 * C57BL/6	increased macrophage nitric oxide production	J:174863
Stat1tm2.1Uvin/Stat1tm2.1Uvin B6.129P2-Stat1tm2.1Uvin	decreased susceptibility to endotoxin shock	J:209388
	normal immune system phenotype	J:209388
	increased susceptibility to bacterial infection	J:209388
	increased susceptibility to bacterial infection induced morbidity/mortality	J:209388
Stat1tm2b(EUCOMM)Wtsi/Stat1tm2b(EUCOMM)Wtsi C57BL/6N-Stat1tm2b(EUCOMM)Wtsi/Orl	abnormal gait	J:211773
	decreased bone mineral content	J:211773
	decreased circulating alkaline phosphatase level	J:211773
	decreased lymphocyte cell number	J:211773
	decreased mean corpuscular hemoglobin	J:211773
	decreased mean corpuscular volume	J:211773
	enlarged lymph nodes	J:211773
	impaired righting response	J:211773
	increased basophil cell number	J:211773
	increased eosinophil cell number	J:211773
	increased large unstained cell number	J:211773
	increased leukocyte cell number	J:211773
	increased lymphocyte cell number	J:211773
	increased monocyte cell number	J:211773
	increased neutrophil cell number	J:211773