Il15 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Il15
interleukin 15
MGI:103014

16 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
\Bcl2l11^tm1.1Ast/\Bcl2l11^tm1.1Ast \Il15^tm1Imx/\Il15^tm1Imx involves: C57BL/6	normal immune system phenotype	J:208318
\Cd8a^tm1Mak/\Cd8a^tm1Mak \Il15^tm1Imx/\Il15^tm1Imx X/\Yaa BXSB.Cg-Cd8a^tm1Mak Il15^tm1Imx/Dcr	abnormal spleen B cell follicle morphology	J:179430
	increased anti-nuclear antigen antibody level	J:179430
	increased IgG1 level	J:179430
	increased IgG2a level	J:179430
	increased IgG2b level	J:179430
	increased monocyte cell number	J:179430
	increased splenocyte number	J:179430
	increased susceptibility to systemic lupus erythematosus	J:179430
	premature death	J:179430
	renal glomerular immunoglobulin deposits	J:179430
\Eomes^tm1.1Twa/? \Il15^tm1Imx/\Il15^tm1Imx involves: C57BL/6 * C57BL/6N	abnormal NK cell differentiation	J:210160
\Il15^tm1Imx/\Il15⁺ \Myc^tm1Atp/\Myc⁺ involves: 129P2/OlaHsd * C57BL/6	decreased memory T cell number	J:132730
\Il15^tm1Imx/\Il15^tm1Imx \Il7r^tm1.1Asin/\Il7r^tm1Imx \Tg(Cd8a-cre)B8Asin/0 involves: 129S7/SvEvBrd C57BL/6	decreased CD8-positive, alpha-beta T cell number	J:190889
\Il15^tm1Imx/\Il15^tm1Imx \Itk^tm1Litt/\Itk^tm1Litt involves: 129S4/SvJae * C57BL/6	abnormal thymus cell ratio	J:111786
\Il15^tm1Imx/\Il15^tm1Imx \Itk^tm1Ljb/\Itk^tm1Ljb involves: 129 * C57BL/6 * C57BL/10	decreased CD8-positive, alpha-beta T cell number	J:113408
\Il15^tm1Imx/\Il15^tm1Imx \Myc^tm1Atp/\Myc⁺ involves: 129P2/OlaHsd * C57BL/6	decreased memory T cell number	J:132730
	decreased NK cell number	J:132730
\Il15^tm1Imx/\Il15^tm1Imx \Rag2^tm1Fwa/\Rag2^tm1Fwa involves: 129S/SvEv * C57BL/6	decreased NK cell number	J:132257
\Il15^tm1Imx/\Il15^tm1Imx X/\Yaa BXSB.B6-Il15^tm1Imx/Dcr	increased susceptibility to systemic lupus erythematosus	J:179430
\Il15^tm1Imx/\Il15^tm1Imx X/\Yaa BXSB.B6-Il15^tm1Imx/Dcr	premature death	J:179430

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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