About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Fstl1
follistatin-like 1
MGI:102793
89 phenotypes from 10 alleles in 10 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Fstl1Gt(P086B03)Wrst/Fstl1Gt(P086B03)Wrst
involves: 129S2/SvPas * ICR
no abnormal phenotype detected J:238836
Fstl1tm1.1Mvdh/Fstl1tm1.1Mvdh
Tg(Myh6-cre)2182Mds/0
involves: 129S4/SvJae * C57BL/6 * FVB/N
abnormal coronary vessel morphology J:177416
abnormal heart septum morphology J:177416
cardiac fibrosis J:177416
cardiac hypertrophy J:177416
decreased angiogenesis J:177416
decreased cardiac muscle contractility J:177416
increased heart left ventricle size J:177416
increased heart left ventricle weight J:177416
increased heart weight J:177416
increased myocardial fiber size J:177416
increased response of heart to induced stress J:177416
pulmonary vascular congestion J:177416
Fstl1tm1.1Ning/Fstl1tm1.1Ning
involves: 129S4/SvJae * C57BL/6J * FVB/N
abnormal breathing pattern J:171347
abnormal bronchiole morphology J:171347
abnormal larynx morphology J:171347
abnormal lung development J:171347
abnormal lung epithelium morphology J:171347
abnormal lung morphology J:171347
abnormal neural tube morphology J:171347
abnormal pulmonary alveolar sac morphology J:171347
abnormal skeleton morphology J:171347
abnormal trachea morphology J:171347
abnormal tracheal cartilage morphology J:171347
abnormal tracheal ciliated epithelium morphology J:171347
abnormal type II pneumocyte morphology J:171347
cyanosis J:171347
decreased alveolar lamellar body number J:171347
decreased surfactant secretion J:171347
decreased tracheal cartilage ring number J:171347
decreased type I pneumocyte number J:171347
hydroureter J:171347
increased glycogen level J:171347
increased type II pneumocyte number J:171347
neonatal lethality, complete penetrance J:171347
primary atelectasis J:171347
pulmonary hyperplasia J:171347
trachea stenosis J:171347
Fstl1tm1.1Nju/Fstl1tm1.1Nju
involves: 129 * C57BL/6 * FVB/N
abnormal kidney pelvis morphology J:187117
abnormal ureter development J:187117
abnormal ureter morphology J:187117
abnormal ureter urothelium morphology J:187117
dilated ureter J:187117
hydronephrosis J:187117
hydroureter J:187117
kidney papillary atrophy J:187117
small kidney J:187117
ureter stenosis J:187117
Fstl1tm1.2Mvdh/Fstl1+
involves: 129S4/SvJae * C57BL/6 * FVB
abnormal rib morphology J:176532
asymmetric sternocostal joints J:176532
Fstl1tm1.2Mvdh/Fstl1tm1.2Mvdh
involves: 129S4/SvJae * C57BL/6 * FVB
abnormal bronchiole morphology J:176532
abnormal cervical atlas morphology J:176532
abnormal cervical axis morphology J:176532
abnormal costal cartilage morphology J:176532
abnormal digit morphology J:176532
abnormal hindlimb stylopod morphology J:176532
abnormal hindlimb zeugopod morphology J:176532
abnormal lung lobe morphology J:176532
abnormal metacarpal bone morphology J:176532
abnormal pulmonary alveolus morphology J:176532
abnormal rib morphology J:176532
abnormal spine curvature J:176532
abnormal tracheal cartilage morphology J:176532
absent patella J:176532
absent sesamoid bone of gastrocnemius J:176532
asymmetric sternocostal joints J:176532
bowed fibula J:176532
camptomelia J:176532
cyanosis J:176532
decreased bone ossification J:176532
fused phalanges J:176532
lordokyphosis J:176532
perinatal lethality, complete penetrance J:176532
primary atelectasis J:176532
respiratory distress J:176532
Fstl1tm1Ajn/Fstl1tm1Ajn
B6.Cg-Fstl1tm1Ajn
abnormal lung hysteresivity J:322116
abnormal lung volume J:322116
abnormal respiratory system physiology J:322116
decreased lung elastance J:322116
emphysema J:322116
increased lung apoptosis J:322116
increased lung compliance J:322116
Fstl1tm1b(EUCOMM)Hmgu/Fstl1tm1b(EUCOMM)Hmgu
C57BL/6N-Fstl1tm1b(EUCOMM)Hmgu/H
decreased fasting circulating glucose level J:211773
decreased neutrophil cell number J:211773
impaired glucose tolerance J:211773
increased circulating cholesterol level J:211773
increased circulating HDL cholesterol level J:211773
increased lymphocyte cell number J:211773
Fstl1tm1Nju/Fstl1tm1Nju
Tg(Scn10a-cre)1Rkun/0
involves: 129 * C57BL/6 * DBA
abnormal action potential J:188549
abnormal dorsal root ganglion morphology J:188549
decreased chemical nociceptive threshold J:188549
decreased thermal nociceptive threshold J:188549
hyperresponsive to tactile stimuli J:188549
increased excitatory postsynaptic current frequency J:188549
Fstl1tm2.1(cre/ERT2)Mvdh/Fstl1+
involves: 129P2/OlaHsd * C57BL/6
abnormal rib morphology J:176532
asymmetric sternocostal joints J:176532
Fstl1tm2.1(cre/ERT2)Mvdh/Fstl1tm2.1(cre/ERT2)Mvdh
involves: 129P2/OlaHsd * C57BL/6
abnormal bronchiole morphology J:176532
abnormal costal cartilage morphology J:176532
abnormal lung lobe morphology J:176532
abnormal pulmonary alveolus morphology J:176532
abnormal rib morphology J:176532
abnormal tracheal cartilage morphology J:176532
asymmetric sternocostal joints J:176532
camptomelia J:176532
cyanosis J:176532
fused phalanges J:176532
perinatal lethality, complete penetrance J:176532
primary atelectasis J:176532
respiratory distress J:176532
Tg(Ckm-Fstl1)#Mvdh/0
involves: C57BL/6
abnormal coronary vessel morphology J:177416
cardiac fibrosis J:177416
decreased cardiac muscle contractility J:177416
decreased response of heart to induced stress J:177416
increased angiogenesis J:177416
increased heart left ventricle weight J:177416
increased heart weight J:177416
increased myocardial fiber size J:177416

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/23/2024
MGI 6.23
The Jackson Laboratory