GO Annotations Graph

• Symbol: Ptprc
• Name: protein tyrosine phosphatase receptor type C
• ID: MGI:97810

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0030506	ankyrin binding	ISO	J:164563
Molecular Function	GO:0043395	heparan sulfate proteoglycan binding	IDA	J:19636
Molecular Function	GO:0008201	heparin binding	IDA	J:19636
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0016791	phosphatase activity	IEA	J:72247
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:200350
Molecular Function	GO:0005515	protein binding	IPI	J:200737
Molecular Function	GO:0005515	protein binding	IPI	J:40482
Molecular Function	GO:0005515	protein binding	IPI	J:40482
Molecular Function	GO:0019901	protein kinase binding	IPI	J:78884
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	IGI	J:265600
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	ISO	J:155856
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	ISO	J:164563
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	IDA	J:213932
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	IDA	J:30241
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	IDA	J:25220
Molecular Function	GO:0005102	signaling receptor binding	IPI	J:265798
Molecular Function	GO:0030507	spectrin binding	ISO	J:164563
Cellular Component	GO:0032059	bleb	ISO	J:164563
Cellular Component	GO:0071944	cell periphery	IDA	J:177992
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0009986	cell surface	IDA	J:94701
Cellular Component	GO:0009898	cytoplasmic side of plasma membrane	NAS	J:96410
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:99189
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:70681
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:125784
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:63425
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:127719
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:84599
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:5707
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:202604
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:97996
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:163829
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:39981
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:25537
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:7488
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:19437
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:29797
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:27768
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:84890
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:31133
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:141377
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:173338
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:163607
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:29797
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:155898
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:155686
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:141184
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:29797
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:29796
Cellular Component	GO:0009897	external side of plasma membrane	ISO	J:145327
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:103896
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:139262
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:143981
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:89320
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:86758
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:157744
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:14194
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:172134
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:89706
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:19636
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:97945
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:33466
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:163607
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:98417
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:91914
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:31364
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:41170
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:132871
Cellular Component	GO:0005925	focal adhesion	IDA	J:114804
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0098857	membrane microdomain	IDA	J:96410
Cellular Component	GO:0045121	membrane raft	IGI	J:265600
Cellular Component	GO:0045121	membrane raft	IDA	J:96410
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IDA	J:89862
Biological Process	GO:0046633	alpha-beta T cell proliferation	IMP	J:25537
Biological Process	GO:0030183	B cell differentiation	IMP	J:94797
Biological Process	GO:0030183	B cell differentiation	IMP	J:131736
Biological Process	GO:0030183	B cell differentiation	IMP	J:33466
Biological Process	GO:0030183	B cell differentiation	IMP	J:84808
Biological Process	GO:0030183	B cell differentiation	IMP	J:42368
Biological Process	GO:0042100	B cell proliferation	IMP	J:13163
Biological Process	GO:0042100	B cell proliferation	IMP	J:30239
Biological Process	GO:0042100	B cell proliferation	IMP	J:33466
Biological Process	GO:0042100	B cell proliferation	IMP	J:42368
Biological Process	GO:0050853	B cell receptor signaling pathway	IMP	J:113679
Biological Process	GO:0050853	B cell receptor signaling pathway	IMP	J:29834
Biological Process	GO:0050853	B cell receptor signaling pathway	IMP	J:42368
Biological Process	GO:0048539	bone marrow development	ISO	J:164563
Biological Process	GO:0035584	calcium-mediated signaling using intracellular calcium source	IGI	J:131736
Biological Process	GO:0044770	cell cycle phase transition	ISO	J:164563
Biological Process	GO:0031668	cellular response to extracellular stimulus	IGI	J:96410
Biological Process	GO:0051607	defense response to virus	IMP	J:13163
Biological Process	GO:0051607	defense response to virus	IDA	J:143981
Biological Process	GO:0016311	dephosphorylation	IDA	J:78884
Biological Process	GO:0097191	extrinsic apoptotic signaling pathway	IMP	J:33466
Biological Process	GO:0042492	gamma-delta T cell differentiation	IMP	J:22470
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	ISO	J:164563
Biological Process	GO:0034113	heterotypic cell-cell adhesion	IMP	J:25220
Biological Process	GO:0007159	leukocyte cell-cell adhesion	IMP	J:25220
Biological Process	GO:0000165	MAPK cascade	IMP	J:42368
Biological Process	GO:0001779	natural killer cell differentiation	IMP	J:94797
Biological Process	GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration	ISO	J:164563
Biological Process	GO:0001960	negative regulation of cytokine-mediated signaling pathway	IDA	J:78884
Biological Process	GO:0070373	negative regulation of ERK1 and ERK2 cascade	IGI	J:96410
Biological Process	GO:0032703	negative regulation of interleukin-2 production	IGI	J:96410
Biological Process	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation	IMP	J:29834
Biological Process	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation	IMP	J:17973
Biological Process	GO:0031953	negative regulation of protein autophosphorylation	IMP	J:17973
Biological Process	GO:0031953	negative regulation of protein autophosphorylation	IMP	J:29834
Biological Process	GO:0031953	negative regulation of protein autophosphorylation	IMP	J:17973
Biological Process	GO:0006469	negative regulation of protein kinase activity	ISO	J:164563
Biological Process	GO:0006469	negative regulation of protein kinase activity	IDA	J:64671
Biological Process	GO:0006469	negative regulation of protein kinase activity	IBA	J:265628
Biological Process	GO:0061099	negative regulation of protein tyrosine kinase activity	IGI	J:96410
Biological Process	GO:0001915	negative regulation of T cell mediated cytotoxicity	IMP	J:111646
Biological Process	GO:0045060	negative thymic T cell selection	IMP	J:33466
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	IMP	J:17973
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	IMP	J:29834
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	IMP	J:29834
Biological Process	GO:0044855	plasma membrane raft distribution	IGI	J:96410
Biological Process	GO:0046641	positive regulation of alpha-beta T cell proliferation	IMP	J:25537
Biological Process	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway	IMP	J:113679
Biological Process	GO:0030890	positive regulation of B cell proliferation	ISO	J:164563
Biological Process	GO:0030890	positive regulation of B cell proliferation	IMP	J:33466
Biological Process	GO:0030890	positive regulation of B cell proliferation	IMP	J:42368
Biological Process	GO:0030890	positive regulation of B cell proliferation	IMP	J:30239
Biological Process	GO:0030890	positive regulation of B cell proliferation	IMP	J:37640
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	IGI	J:96410
Biological Process	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	IMP	J:33466
Biological Process	GO:1905451	positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis	IGI	J:131736
Biological Process	GO:0045588	positive regulation of gamma-delta T cell differentiation	IMP	J:22470
Biological Process	GO:2000473	positive regulation of hematopoietic stem cell migration	ISO	J:164563
Biological Process	GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin	IMP	J:30239
Biological Process	GO:0002639	positive regulation of immunoglobulin production	ISO	J:164563
Biological Process	GO:0032743	positive regulation of interleukin-2 production	IGI	J:96410
Biological Process	GO:0048304	positive regulation of isotype switching to IgG isotypes	IMP	J:37640
Biological Process	GO:0043406	positive regulation of MAP kinase activity	IMP	J:42368
Biological Process	GO:0043410	positive regulation of MAPK cascade	IGI	J:131736
Biological Process	GO:0043410	positive regulation of MAPK cascade	IMP	J:42368
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	IGI	J:131736
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	IBA	J:265628
Biological Process	GO:1903615	positive regulation of protein tyrosine phosphatase activity	IGI	J:96410
Biological Process	GO:2000648	positive regulation of stem cell proliferation	ISO	J:164563
Biological Process	GO:0045582	positive regulation of T cell differentiation	IMP	J:33466
Biological Process	GO:0001916	positive regulation of T cell mediated cytotoxicity	IMP	J:7453
Biological Process	GO:0002711	positive regulation of T cell mediated immunity	IMP	J:7453
Biological Process	GO:0002711	positive regulation of T cell mediated immunity	IMP	J:30239
Biological Process	GO:0042102	positive regulation of T cell proliferation	IMP	J:13163
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	IGI	J:131736
Biological Process	GO:0045059	positive thymic T cell selection	IMP	J:33466
Biological Process	GO:0046777	protein autophosphorylation	IMP	J:17973
Biological Process	GO:0046777	protein autophosphorylation	IMP	J:29834
Biological Process	GO:0046777	protein autophosphorylation	IMP	J:17973
Biological Process	GO:0046777	protein autophosphorylation	IMP	J:29834
Biological Process	GO:0006470	protein dephosphorylation	IDA	J:114804
Biological Process	GO:0006470	protein dephosphorylation	IBA	J:265628
Biological Process	GO:0051726	regulation of cell cycle	IDA	J:64671
Biological Process	GO:2001236	regulation of extrinsic apoptotic signaling pathway	IMP	J:25220
Biological Process	GO:0010468	regulation of gene expression	IGI	J:265600
Biological Process	GO:0010468	regulation of gene expression	ISO	J:155856
Biological Process	GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin	IMP	J:37640
Biological Process	GO:0032677	regulation of interleukin-8 production	ISO	J:164563
Biological Process	GO:0050764	regulation of phagocytosis	ISO	J:164563
Biological Process	GO:0061097	regulation of protein tyrosine kinase activity	ISO	J:164563
Biological Process	GO:0046425	regulation of receptor signaling pathway via JAK-STAT	ISO	J:164563
Biological Process	GO:0051209	release of sequestered calcium ion into cytosol	IDA	J:57681
Biological Process	GO:0010332	response to gamma radiation	ISO	J:155856
Biological Process	GO:0048864	stem cell development	ISO	J:164563
Biological Process	GO:0030217	T cell differentiation	IMP	J:94797
Biological Process	GO:0030217	T cell differentiation	IMP	J:13163
Biological Process	GO:0042098	T cell proliferation	IMP	J:84808
Biological Process	GO:0050852	T cell receptor signaling pathway	ISO	J:155856
Biological Process	GO:0050852	T cell receptor signaling pathway	ISO	J:164563
Biological Process	GO:0050852	T cell receptor signaling pathway	IGI	J:265600