Brd10 MGI Mouse Gene Detail - MGI:2444398 - bromodomain containing 10

Symbol

Brd10
Name

bromodomain containing 10
Synonyms

9930021J03Rik, Gm9832

Feature Type

protein coding gene
IDs

MGI:2444398
NCBI Gene: 240613
Alliance

gene page
Transcription Start Sites

3 TSS

Sequence Map

Chr19:29691802-29783389 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 19, 24.30 cM
Mapping Data

2 experiments

SNPs within 2kb

1668 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2444398	protein coding gene	Chr19:29691802-29784273 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0025027	protein coding gene	Chr19:28190366-28282162 (-)
A/J	MGP_AJ_G0025004	protein coding gene	Chr19:26782899-26875722 (-)
AKR/J	MGP_AKRJ_G0024972	protein coding gene	Chr19:27729436-27827655 (-)
BALB/cJ	MGP_BALBcJ_G0025003	protein coding gene	Chr19:26818247-26912474 (-)
C3H/HeJ	MGP_C3HHeJ_G0024759	protein coding gene	Chr19:27707643-27803962 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0025444	protein coding gene	Chr19:28956588-29050363 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0022863	protein coding gene	Chr19:26727785-26822100 (-)
CAST/EiJ	MGP_CASTEiJ_G0024229	protein coding gene	Chr19:27544136-27642948 (-)
CBA/J	MGP_CBAJ_G0024737	protein coding gene	Chr19:30315125-30423606 (-)
DBA/2J	MGP_DBA2J_G0024869	protein coding gene	Chr19:26727629-26821954 (-)
FVB/NJ	MGP_FVBNJ_G0024831	protein coding gene	Chr19:26571975-26662112 (-)
LP/J	MGP_LPJ_G0024954	protein coding gene	Chr19:28181237-28279926 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0024858	protein coding gene	Chr19:30248305-30346806 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0025499	protein coding gene	Chr19:27754377-27847935 (-)
PWK/PhJ	MGP_PWKPhJ_G0023977	protein coding gene	Chr19:26392482-26486398 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0023781	protein coding gene	Chr19:27035981-27136914 (-)
WSB/EiJ	MGP_WSBEiJ_G0024296	protein coding gene	Chr19:27798876-27891447 (-)

Human Ortholog

BRD10, bromodomain containing 10

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

BRD10, bromodomain containing 10
Synonyms

KIAA2026
Links

HGNC:23378

NCBI Gene ID: 158358

UniProt: Q5HYC2
Chr Location

9p24.1; chr9:5878834-6008482 (-) GRCh38

MGI Vertebrate Homology

Brd10 stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: BRD10
Gene Tree

Brd10

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Phenotype Summary

5 phenotypes from 1 allele in 1 genetic background
8 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

12
Endonuclease-mediated

1
Gene trapped

6
Targeted

5
Genomic Mutations

4 involving Brd10
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

71 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.

Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

715
Tissues

2
cDNA Data

49
Literature Summary

1

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase brd10

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All Sequences

78
RefSeq

27
UniProt

8

Ensembl

ENSMUSG00000046138 (Evidence)
NCBI Gene

240613

			Length	Strain/Species	Flank
genomic	ENSMUSG00000046138	Ensembl Gene Model \| MGI Sequence Detail	91588	C57BL/6J	± kb
transcript	ENSMUST00000177155	Ensembl \| MGI Sequence Detail	6632	Not Applicable
polypeptide	ENSMUSP00000135473	Ensembl \| MGI Sequence Detail	2027	Not Applicable

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UniProt

8 Sequences
InterPro Domains

IPR001487 Bromodomain

IPR036427 Bromodomain-like superfamily

IPR040214 Uncharacterized bromodomain-containing protein 10
GlyGen

H3BKP8 2 sites, 1 O-linked glycan (1 site)

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All nucleic 50

cDNA 50

Microarray probesets 4

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MGI:3704495, MGI:7532533

Summaries

All 24

Developmental Gene Expression 1

Phenotypes 8
Earliest

J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
Latest

J:360836 Kambali M, et al., An increased copy number of glycine decarboxylase (GLDC) associated with psychosis reduces extracellular glycine and impairs NMDA receptor function. Mol Psychiatry. 2024 Aug 30;

TSS for Brd10:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr158788	Chr19:29783931-29783952 (-)	-553 bp
Tssr158787	Chr19:29783784-29783835 (-)	-421 bp
Tssr158786	Chr19:29764706-29764712 (-)	18,680 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 01/28/2026 MGI 6.24