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Tmem270 Gene Detail
Summary
  • Symbol
    Tmem270
  • Name
    transmembrane protein 270
  • Synonyms
    1700111I05Rik, Wbscr28
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923879
    NCBI Gene: 76629
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:134930447-134935587 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 74.88 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    12 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923879
 protein coding gene Chr5:134930447-134935587 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030164
 protein coding gene Chr5:139361978-139367118 (-)
A/J MGP_AJ_G0030132
 protein coding gene Chr5:133424454-133429500 (-)
AKR/J MGP_AKRJ_G0030065
 protein coding gene Chr5:137766051-137770782 (-)
BALB/cJ MGP_BALBcJ_G0030142
 protein coding gene Chr5:134779046-134784312 (-)
C3H/HeJ MGP_C3HHeJ_G0029858
 protein coding gene Chr5:138318678-138323660 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030595
 protein coding gene Chr5:144593002-144597413 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027819
 protein coding gene Chr5:127718069-127722855 (-)
CAST/EiJ MGP_CASTEiJ_G0029267
 protein coding gene Chr5:137745123-137752227 (-)
CBA/J MGP_CBAJ_G0029828
 protein coding gene Chr5:150251163-150258025 (-)
DBA/2J MGP_DBA2J_G0029979
 protein coding gene Chr5:133319666-133325139 (-)
FVB/NJ MGP_FVBNJ_G0029934
 protein coding gene Chr5:132451378-132456423 (-)
LP/J MGP_LPJ_G0030067
 protein coding gene Chr5:139828530-139833670 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029966
 protein coding gene Chr5:153273164-153280779 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030635
 protein coding gene Chr5:137497224-137502364 (-)
PWK/PhJ MGP_PWKPhJ_G0028982
 protein coding gene Chr5:132361635-132367266 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028817
 protein coding gene Chr5:135071708-135076031 (-)
WSB/EiJ MGP_WSBEiJ_G0029341
 protein coding gene Chr5:138250829-138255966 (-)



Homology
more
  • Human Ortholog
    TMEM270, transmembrane protein 270
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM270, transmembrane protein 270
  • Synonyms
    WBSCR28
  • Links
    NCBI Gene ID: 135886
    neXtProt AC: NX_Q6UE05
    UniProt: Q6UE05

  • Chr Location
    7q11.23; chr7:73860848-73865890 (+)  GRCh38
Human Diseases
less
  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    15 phenotype references
Male mice homozygous for a null allele exhibit normal fecundity.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 76629 NCBI Gene Model | MGI Sequence Detail 5141 C57BL/6J ±  kb
transcript NM_029681 RefSeq | MGI Sequence Detail 933 C57BL/6  
polypeptide Q6UJB9 UniProt | EBI | MGI Sequence Detail 264 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 4
    Genomic 1
    cDNA 3

    Microarray probesets 2
References
more
  • Summaries
    All 32
    Diseases 2
    Gene Ontology 1
    Phenotypes 15
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:337436 Abdalla N, et al., Dysfunctional Mitochondria in the Cardiac Fibers of a Williams-Beuren Syndrome Mouse Model. Int J Mol Sci. 2023 Jun 13;24(12)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory