About   Help   FAQ
Cox7a2 Gene Detail
Summary
  • Symbol
    Cox7a2
  • Name
    cytochrome c oxidase subunit 7A2
  • Synonyms
    Cox7a3, COX7AL
  • Feature Type
    protein coding gene
  • IDs
    MGI:1316715
    NCBI Gene: 12866
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:79662643-79667160 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 43.82 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    70 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1316715
 protein coding gene Chr9:79662523-79667160 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035075
 protein coding gene Chr9:80292657-80297283 (-)
A/J MGP_AJ_G0035056
 protein coding gene Chr9:77550789-77555403 (-)
AKR/J MGP_AKRJ_G0034984
 protein coding gene Chr9:79353431-79358049 (-)
BALB/cJ MGP_BALBcJ_G0035044
 protein coding gene Chr9:77171914-77176526 (-)
C3H/HeJ MGP_C3HHeJ_G0034756
 protein coding gene Chr9:79877190-79881842 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035567
 protein coding gene Chr9:82480412-82485023 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032474
 protein coding gene Chr9:76687009-76691516 (-)
CAST/EiJ MGP_CASTEiJ_G0034074
 protein coding gene Chr9:80211135-80215612 (-)
CBA/J MGP_CBAJ_G0034729
 protein coding gene Chr9:85413953-85422561 (-)
DBA/2J MGP_DBA2J_G0034887
 protein coding gene Chr9:77158792-77163407 (-)
FVB/NJ MGP_FVBNJ_G0034830
 protein coding gene Chr9:76375475-76380088 (-)
LP/J MGP_LPJ_G0034968
 protein coding gene Chr9:80550250-80554876 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034872
 protein coding gene Chr9:86654085-86661477 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035588
 protein coding gene Chr9:79572417-79577030 (-)
PWK/PhJ MGP_PWKPhJ_G0033778
 protein coding gene Chr9:77358855-77363682 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033614
 protein coding gene Chr9:79709539-79714145 (-)
WSB/EiJ MGP_WSBEiJ_G0034191
 protein coding gene Chr9:79510690-79515637 (-)



Homology
more
  • Human Ortholog
    COX7A2, cytochrome c oxidase subunit 7A2
  • Vertebrate Orthologs
    6
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    COX7A2, cytochrome c oxidase subunit 7A2
  • Synonyms
    COX7AL, COX7AL1, COXVIIa-L, COXVIIAL, VIIAL
  • Links
    NCBI Gene ID: 1347
    neXtProt AC: NX_P14406
    UniProt: P14406

  • Chr Location
    6q14.1; chr6:75237675-75250323 (-)  GRCh38
  • Human Ortholog
    COX7A2P2, cytochrome c oxidase subunit 7A2 pseudogene 2
  • Synonyms
    COX7A3, COX7AL, COX7AL2, COX7AP2
  • Links
    NCBI Gene ID: 1348
    UniProt: O60397

  • Chr Location
    4q22.3; chr4:96902763-96903189 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
  • All Mutations and Alleles
    18
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    12
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    2 involving Cox7a2
  • Incidental Mutations
    APF , CvDC
  • Find Mice (IMSR)
    13 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    812
  • Tissues
    106
  • cDNA Data
    280
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032330 Ensembl Gene Model | MGI Sequence Detail 4518 C57BL/6J ±  kb
transcript ENSMUST00000034881 Ensembl | MGI Sequence Detail 659 Not Applicable  
polypeptide ENSMUSP00000034881 Ensembl | MGI Sequence Detail 83 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000005787 cytochrome c oxidase subunit 7A2, mitochondrial
    (term hierarchy)
  • InterPro Domains
    IPR039297 Cytochrome c oxidase subunit VII
    IPR003177 Cytochrome c oxidase subunit VIIa, metazoa
    IPR036539 Cytochrome c oxidase, subunit VIIa superfamily
Molecular
Reagents
less
  • All nucleic 281
    cDNA 280
    Primer pair 1

    Microarray probesets 5
References
more
  • Summaries
    All 45
    Developmental Gene Expression 2
    Gene Ontology 8
    Phenotypes 13
  • Earliest
    J:12013 Russell LB, Definition of functional units in a small chromosomal segment of the mouse and its use in interpreting the nature of radiation-induced mutations. Mutat Res. 1971 Jan;11(1):107-23
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory