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Phenotype Images associated with this Gene
Symbol
Name
ID
Gba
glucosidase, beta, acid
MGI:95665


11 phenotype image(s) for Gba alleles
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Caption: Gbatm2Karl/Gbatm2Karl Tg(KRT14-cre)8Brn/? mice display a severe and rapidly progressive neurological disease (details)
Represented Alleles:
Gbatm2Karl, glucosidase, beta, acid; targeted mutation 2, Stefan Karlsson
Tg(KRT14-cre)8Brn, transgene insertion 8, Anton Berns
Copyright: This image is from Enquist IB, Proc Natl Acad Sci U S A 2007 Oct 30;104(44):17483-8. Copyright 2007 National Academy of Sciences, U.S.A. J:127108
Caption: Gbatm2Karl/Gbatm2Karl (upper left) mice display a lethal skin phenotype whileGbatm2Karl/Gbatm2Karl Tg(KRT14-cre)8Brn/? (lower) mice display paralysis (details)
Represented Alleles:
Gbatm2Karl, glucosidase, beta, acid; targeted mutation 2, Stefan Karlsson
Tg(KRT14-cre)8Brn, transgene insertion 8, Anton Berns
Copyright: This image is from Enquist IB, Proc Natl Acad Sci U S A 2007 Oct 30;104(44):17483-8. Copyright 2007 National Academy of Sciences, U.S.A. J:127108
Caption: Gbatm1Karl/Gbatm1Karl Tg(Nes-cre)1Kln/? mice exhibit a more profound activation and proliferation of microglial cells than Gbatm2Karl/Gbatm2Karl Tg(KRT14-cre)8Brn/? mice (details)
Represented Alleles:
Gbatm1Karl, glucosidase, beta, acid; targeted mutation 1, Stefan Karlsson
Gbatm2Karl, glucosidase, beta, acid; targeted mutation 2, Stefan Karlsson
Tg(Nes-cre)1Kln, transgene insertion 1, Rudiger Klein
Copyright: This image is from Enquist IB, Proc Natl Acad Sci U S A 2007 Oct 30;104(44):17483-8. Copyright 2007 National Academy of Sciences, U.S.A. J:127108
Caption: Gbatm2Karl/Gbatm2Karl Tg(KRT14-cre)8Brn/? mice display Gaucher cells in the liver and spleen (details)
Represented Alleles:
Gbatm2Karl, glucosidase, beta, acid; targeted mutation 2, Stefan Karlsson
Tg(KRT14-cre)8Brn, transgene insertion 8, Anton Berns
Copyright: This image is from Enquist IB, Proc Natl Acad Sci U S A 2007 Oct 30;104(44):17483-8. Copyright 2007 National Academy of Sciences, U.S.A. J:127108
Caption: Neuronal loss in Gbatm2Karl/Gbatm2Karl Tg(KRT14-cre)8Brn/? mice (details)
Represented Alleles:
Gbatm2Karl, glucosidase, beta, acid; targeted mutation 2, Stefan Karlsson
Tg(KRT14-cre)8Brn, transgene insertion 8, Anton Berns
Copyright: This image is from Enquist IB, Proc Natl Acad Sci U S A 2007 Oct 30;104(44):17483-8. Copyright 2007 National Academy of Sciences, U.S.A. J:127108
Caption: Gbatm2Karl/Gbatm2Karl Tg(KRT14-cre)8Brn/? mice display astrogliosis and abnormal microglia (details)
Represented Alleles:
Gbatm2Karl, glucosidase, beta, acid; targeted mutation 2, Stefan Karlsson
Tg(KRT14-cre)8Brn, transgene insertion 8, Anton Berns
Copyright: This image is from Enquist IB, Proc Natl Acad Sci U S A 2007 Oct 30;104(44):17483-8. Copyright 2007 National Academy of Sciences, U.S.A. J:127108
Caption: Inflammatory reaction in the liver of Gbatm1Rlp/Gbatm1Rlp mice (details)
Represented Alleles:
Gbatm1Rlp, glucosidase, beta, acid; targeted mutation 1, Richard L Proia
Copyright: This image is from Mizukami H, J Clin Invest 2002 May;109(9):1215-21 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:76409
Caption: Abnormal macrophages with lipofuscin granules and tubular structures in livers of Gbatm1Rlp/Gbatm1Rlp mice (details)
Represented Alleles:
Gbatm1Rlp, glucosidase, beta, acid; targeted mutation 1, Richard L Proia
Copyright: This image is from Mizukami H, J Clin Invest 2002 May;109(9):1215-21 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:76409
Caption: Lung and skin inflammation and thicker stratum corneum and epidermis in Gbatm1Rlp/Gbatm1Rlp mice (details)
Represented Alleles:
Gbatm1Rlp, glucosidase, beta, acid; targeted mutation 1, Richard L Proia
Copyright: This image is from Mizukami H, J Clin Invest 2002 May;109(9):1215-21 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:76409
Caption: Lymph node hypertrophy in the Gbatm1Rlp/Gbatm1Rlp mice (details)
Represented Alleles:
Gbatm1Rlp, glucosidase, beta, acid; targeted mutation 1, Richard L Proia
Copyright: This image is from Mizukami H, J Clin Invest 2002 May;109(9):1215-21 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:76409

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/24/2023
MGI 6.22
The Jackson Laboratory