Phenotype Images associated with this Gene

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Phenotype Images associated with this Gene

Symbol
Name
ID

Gba
glucosidase, beta, acid
MGI:95665

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Click on allele symbol for full phenotype details.

	Caption: Gba^tm2Karl/Gba^tm2Karl Tg(KRT14-cre)8Brn/? mice display a severe and rapidly progressive neurological disease (details) Represented Alleles: Gba^tm2Karl, glucosidase, beta, acid; targeted mutation 2, Stefan Karlsson Tg(KRT14-cre)8Brn, transgene insertion 8, Anton Berns Copyright: This image is from Enquist IB, Proc Natl Acad Sci U S A 2007 Oct 30;104(44):17483-8. Copyright 2007 National Academy of Sciences, U.S.A. J:127108
	Caption: Gba^tm2Karl/Gba^tm2Karl (upper left) mice display a lethal skin phenotype whileGba^tm2Karl/Gba^tm2Karl Tg(KRT14-cre)8Brn/? (lower) mice display paralysis (details) Represented Alleles: Gba^tm2Karl, glucosidase, beta, acid; targeted mutation 2, Stefan Karlsson Tg(KRT14-cre)8Brn, transgene insertion 8, Anton Berns Copyright: This image is from Enquist IB, Proc Natl Acad Sci U S A 2007 Oct 30;104(44):17483-8. Copyright 2007 National Academy of Sciences, U.S.A. J:127108
	Caption: Gba^tm1Karl/Gba^tm1Karl Tg(Nes-cre)1Kln/? mice exhibit a more profound activation and proliferation of microglial cells than Gba^tm2Karl/Gba^tm2Karl Tg(KRT14-cre)8Brn/? mice (details) Represented Alleles: Gba^tm1Karl, glucosidase, beta, acid; targeted mutation 1, Stefan Karlsson Gba^tm2Karl, glucosidase, beta, acid; targeted mutation 2, Stefan Karlsson Tg(Nes-cre)1Kln, transgene insertion 1, Rudiger Klein Copyright: This image is from Enquist IB, Proc Natl Acad Sci U S A 2007 Oct 30;104(44):17483-8. Copyright 2007 National Academy of Sciences, U.S.A. J:127108
	Caption: Gba^tm2Karl/Gba^tm2Karl Tg(KRT14-cre)8Brn/? mice display Gaucher cells in the liver and spleen (details) Represented Alleles: Gba^tm2Karl, glucosidase, beta, acid; targeted mutation 2, Stefan Karlsson Tg(KRT14-cre)8Brn, transgene insertion 8, Anton Berns Copyright: This image is from Enquist IB, Proc Natl Acad Sci U S A 2007 Oct 30;104(44):17483-8. Copyright 2007 National Academy of Sciences, U.S.A. J:127108
	Caption: Neuronal loss in Gba^tm2Karl/Gba^tm2Karl Tg(KRT14-cre)8Brn/? mice (details) Represented Alleles: Gba^tm2Karl, glucosidase, beta, acid; targeted mutation 2, Stefan Karlsson Tg(KRT14-cre)8Brn, transgene insertion 8, Anton Berns Copyright: This image is from Enquist IB, Proc Natl Acad Sci U S A 2007 Oct 30;104(44):17483-8. Copyright 2007 National Academy of Sciences, U.S.A. J:127108
	Caption: Gba^tm2Karl/Gba^tm2Karl Tg(KRT14-cre)8Brn/? mice display astrogliosis and abnormal microglia (details) Represented Alleles: Gba^tm2Karl, glucosidase, beta, acid; targeted mutation 2, Stefan Karlsson Tg(KRT14-cre)8Brn, transgene insertion 8, Anton Berns Copyright: This image is from Enquist IB, Proc Natl Acad Sci U S A 2007 Oct 30;104(44):17483-8. Copyright 2007 National Academy of Sciences, U.S.A. J:127108
	Caption: Inflammatory reaction in the liver of Gba^tm1Rlp/Gba^tm1Rlp mice (details) Represented Alleles: Gba^tm1Rlp, glucosidase, beta, acid; targeted mutation 1, Richard L Proia Copyright: This image is from Mizukami H, J Clin Invest 2002 May;109(9):1215-21 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:76409
	Caption: Abnormal macrophages with lipofuscin granules and tubular structures in livers of Gba^tm1Rlp/Gba^tm1Rlp mice (details) Represented Alleles: Gba^tm1Rlp, glucosidase, beta, acid; targeted mutation 1, Richard L Proia Copyright: This image is from Mizukami H, J Clin Invest 2002 May;109(9):1215-21 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:76409
	Caption: Lung and skin inflammation and thicker stratum corneum and epidermis in Gba^tm1Rlp/Gba^tm1Rlp mice (details) Represented Alleles: Gba^tm1Rlp, glucosidase, beta, acid; targeted mutation 1, Richard L Proia Copyright: This image is from Mizukami H, J Clin Invest 2002 May;109(9):1215-21 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:76409
	Caption: Lymph node hypertrophy in the Gba^tm1Rlp/Gba^tm1Rlp mice (details) Represented Alleles: Gba^tm1Rlp, glucosidase, beta, acid; targeted mutation 1, Richard L Proia Copyright: This image is from Mizukami H, J Clin Invest 2002 May;109(9):1215-21 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:76409

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