Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes VIP
  • Mouse genes Vip
  • Rat genes Vip
  • Zfish genes vip,vipb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Vip

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005179	hormone activity	VIP	IDA		Human	PMID:9603988
Molecular Function	GO:0005179	hormone activity	Vip	IDA		Mouse	MGI:MGI:5318038|PMID:9603988
Molecular Function	GO:0005179	hormone activity	Vip	IDA		Rat	PMID:9603988|RGD:8554017
Molecular Function	GO:0005179	hormone activity	vip	IDA		Zfish	PMID:18757498
Molecular Function	GO:0051428	peptide hormone receptor binding	VIP	IPI	UniProtKB:P32241	Human	PMID:8390245
Molecular Function	GO:0005515	protein binding	VIP	IPI	UniProtKB:P27487	Human	PMID:21314817
Molecular Function	GO:0005515	protein binding	VIP	IPI	UniProtKB:Q12884	Human	PMID:21314817
Molecular Function	GO:0005515	protein binding	VIP	IPI	UniProtKB:O43765	Human	PMID:25416956
Molecular Function	GO:0005102	signaling receptor binding	Vip	IDA		Rat	PMID:1314625|RGD:727528
Cellular Component	GO:0043025	neuronal cell body	Vip	IDA		Rat	PMID:22108610|RGD:5685627
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	VIP	IDA		Human	PMID:9603988
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	Vip	IDA		Mouse	MGI:MGI:5318038|PMID:9603988
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	Vip	IDA		Rat	PMID:9603988|RGD:8554017
Biological Process	GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	vip	IDA		Zfish	PMID:18757498
Biological Process	GO:0007611	learning or memory	Vip	IDA		Rat	PMID:19465061|RGD:5685635
Biological Process	GO:0043066	negative regulation of apoptotic process	Vip	IDA		Rat	PMID:21850490|RGD:5685378
Biological Process	GO:0043267	negative regulation of potassium ion transport	Vip	IDA		Rat	PMID:20699230|RGD:5685630
Biological Process	GO:0048662	negative regulation of smooth muscle cell proliferation	Vip	IMP		Rat	PMID:20452385|RGD:5685633
Biological Process	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	vip	IDA		Zfish	PMID:18757498
Biological Process	GO:0001938	positive regulation of endothelial cell proliferation	Vip	IDA		Rat	PMID:19332106|RGD:5685636
Biological Process	GO:0060406	positive regulation of penile erection	Vip	IDA		Rat	PMID:21166748|RGD:5685628
Biological Process	GO:0045732	positive regulation of protein catabolic process	VIP	IDA		Human	PMID:9603988
Biological Process	GO:0045732	positive regulation of protein catabolic process	Vip	IDA		Mouse	MGI:MGI:5318038|PMID:9603988
Biological Process	GO:0045732	positive regulation of protein catabolic process	Vip	IDA		Rat	PMID:9603988|RGD:8554017
Biological Process	GO:0032880	regulation of protein localization	VIP	IDA		Human	PMID:9603988
Biological Process	GO:0032880	regulation of protein localization	Vip	IDA		Mouse	MGI:MGI:5318038|PMID:9603988
Biological Process	GO:0032880	regulation of protein localization	Vip	IDA		Rat	PMID:9603988|RGD:8554017
Biological Process	GO:0051930	regulation of sensory perception of pain	Vip	IDA		Rat	PMID:19467283|RGD:5685608
Biological Process	GO:0009966	regulation of signal transduction	Vip	IMP		Mouse	PMID:21737879
Biological Process	GO:0007165	signal transduction	vip	IDA		Zfish	PMID:18757498|ZFIN:ZDB-PUB-080902-28

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern