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Term Detail
GO term:phospholipase C-activating G-protein coupled receptor signaling pathway
Synonym: activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger
Synonym: G-protein coupled receptor signaling pathway coupled to IP3 second messenger
Synonym: G protein signaling, coupled to IP3 second messenger (phospholipase C activating)
Synonym: G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)
Synonym: G protein signalling, coupled to IP3 second messenger (phospholipase C activating)
Synonym: G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)
Synonym: phospholipase C-activating dopamine receptor signaling pathway
Synonym: PLC-activating GPCR signaling pathway
GO id:GO:0007200
Definition:The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent increase in the concentration of inositol trisphosphate (IP3) and diacylglycerol (DAG).
CommentsThis term is intended to cover steps in a GPCR signaling pathway both upstream and downstream of phospholipase C (PLC) activity.
Number of paths to term: 9

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                is-acell surface receptor signaling pathway
                                                        is-aG-protein coupled receptor signaling pathway
                                                                is-aadrenergic receptor signaling pathway +
                                                                is-aangiotensin-activated signaling pathway +
                                                                is-aapelin receptor signaling pathway
                                                                is-abombesin receptor signaling pathway
                                                                is-acannabinoid signaling pathway +
                                                                is-acholecystokinin signaling pathway +
                                                                is-acomplement component C5a signaling pathway
                                                                is-adimeric G-protein coupled receptor signaling pathway +
                                                                is-adopamine receptor signaling pathway +
                                                                is-aendothelin receptor signaling pathway +
                                                                is-aepidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway
                                                                is-afollicle-stimulating hormone signaling pathway
                                                                is-aG-protein coupled acetylcholine receptor signaling pathway +
                                                                is-aG-protein coupled glutamate receptor signaling pathway +
                                                                is-aG-protein coupled purinergic receptor signaling pathway +
                                                                is-aG-protein coupled receptor signaling in absence of ligand
                                                                is-aG-protein coupled receptor signaling pathway involved in heart process +
                                                                is-aG-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger +
                                                                is-aG-protein coupled receptor signaling pathway, coupled to S1P second messenger
                                                                is-agamma-aminobutyric acid signaling pathway
                                                                is-agastric inhibitory peptide signaling pathway
                                                                part-ofheterotrimeric G-protein complex cycle
                                                                is-aluteinizing hormone signaling pathway +
                                                                negatively-regulatesnegative regulation of G-protein coupled receptor protein signaling pathway +
                                                                is-aneuropeptide signaling pathway
                                                                is-aoctopamine or tyramine signaling pathway +
                                                                is-aopioid receptor signaling pathway +
                                                                is-apheromone-dependent signal transduction involved in conjugation with cellular fusion +
                                                                is-aphospholipase C-activating G-protein coupled receptor signaling pathway [GO:0007200] (59 genes, 81 annotations)
                                                                        negatively-regulatesnegative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                        is-aphospholipase C-activating adrenergic receptor signaling pathway
                                                                        is-aphospholipase C-activating angiotensin-activated signaling pathway +
                                                                        is-aphospholipase C-activating dopamine receptor signaling pathway +
                                                                        is-aphospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway
                                                                        is-aphospholipase C-activating G-protein coupled glutamate receptor signaling pathway
                                                                        is-aphospholipase C-activating rhodopsin mediated signaling pathway
                                                                        is-aphospholipase C-activating serotonin receptor signaling pathway
                                                                        is-aphospholipase C-activating tachykinin receptor signaling pathway
                                                                        part-ofpositive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
                                                                        positively-regulatespositive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway
                                                                        regulatesregulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                is-aphospholipase C-inhibiting G-protein coupled receptor signaling pathway
                                                                is-aphospholipase D-activating G-protein coupled receptor signaling pathway
                                                                positively-regulatespositive regulation of G-protein coupled receptor protein signaling pathway +
                                                                is-aprotein kinase C-activating G-protein coupled receptor signaling pathway
                                                                regulatesregulation of G-protein coupled receptor protein signaling pathway +
                                                                is-arhodopsin mediated signaling pathway +
                                                                is-aserotonin receptor signaling pathway +
                                                                is-asignal transduction involved in conjugation with mutual genetic exchange
                                                                is-asomatostatin receptor signaling pathway +
                                                                is-asphingosine-1-phosphate signaling pathway +
                                                                is-atachykinin receptor signaling pathway +
                                                                is-athrombin receptor signaling pathway +
                                                                is-athromboxane A2 signaling pathway
                                                                is-athyroid-stimulating hormone signaling pathway


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aG-protein coupled receptor signaling pathway
                                                        is-aadrenergic receptor signaling pathway +
                                                        is-aangiotensin-activated signaling pathway +
                                                        is-aapelin receptor signaling pathway
                                                        is-abombesin receptor signaling pathway
                                                        is-acannabinoid signaling pathway +
                                                        is-acholecystokinin signaling pathway +
                                                        is-acomplement component C5a signaling pathway
                                                        is-adimeric G-protein coupled receptor signaling pathway +
                                                        is-adopamine receptor signaling pathway +
                                                        is-aendothelin receptor signaling pathway +
                                                        is-aepidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway
                                                        is-afollicle-stimulating hormone signaling pathway
                                                        is-aG-protein coupled acetylcholine receptor signaling pathway +
                                                        is-aG-protein coupled glutamate receptor signaling pathway +
                                                        is-aG-protein coupled purinergic receptor signaling pathway +
                                                        is-aG-protein coupled receptor signaling in absence of ligand
                                                        is-aG-protein coupled receptor signaling pathway involved in heart process +
                                                        is-aG-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger +
                                                        is-aG-protein coupled receptor signaling pathway, coupled to S1P second messenger
                                                        is-agamma-aminobutyric acid signaling pathway
                                                        is-agastric inhibitory peptide signaling pathway
                                                        part-ofheterotrimeric G-protein complex cycle
                                                        is-aluteinizing hormone signaling pathway +
                                                        negatively-regulatesnegative regulation of G-protein coupled receptor protein signaling pathway +
                                                        is-aneuropeptide signaling pathway
                                                        is-aoctopamine or tyramine signaling pathway +
                                                        is-aopioid receptor signaling pathway +
                                                        is-apheromone-dependent signal transduction involved in conjugation with cellular fusion +
                                                        is-aphospholipase C-activating G-protein coupled receptor signaling pathway [GO:0007200] (59 genes, 81 annotations)
                                                                negatively-regulatesnegative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                is-aphospholipase C-activating adrenergic receptor signaling pathway
                                                                is-aphospholipase C-activating angiotensin-activated signaling pathway +
                                                                is-aphospholipase C-activating dopamine receptor signaling pathway +
                                                                is-aphospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway
                                                                is-aphospholipase C-activating G-protein coupled glutamate receptor signaling pathway
                                                                is-aphospholipase C-activating rhodopsin mediated signaling pathway
                                                                is-aphospholipase C-activating serotonin receptor signaling pathway
                                                                is-aphospholipase C-activating tachykinin receptor signaling pathway
                                                                part-ofpositive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
                                                                positively-regulatespositive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway
                                                                regulatesregulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                        is-aphospholipase C-inhibiting G-protein coupled receptor signaling pathway
                                                        is-aphospholipase D-activating G-protein coupled receptor signaling pathway
                                                        positively-regulatespositive regulation of G-protein coupled receptor protein signaling pathway +
                                                        is-aprotein kinase C-activating G-protein coupled receptor signaling pathway
                                                        regulatesregulation of G-protein coupled receptor protein signaling pathway +
                                                        is-arhodopsin mediated signaling pathway +
                                                        is-aserotonin receptor signaling pathway +
                                                        is-asignal transduction involved in conjugation with mutual genetic exchange
                                                        is-asomatostatin receptor signaling pathway +
                                                        is-asphingosine-1-phosphate signaling pathway +
                                                        is-atachykinin receptor signaling pathway +
                                                        is-athrombin receptor signaling pathway +
                                                        is-athromboxane A2 signaling pathway
                                                        is-athyroid-stimulating hormone signaling pathway


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aG-protein coupled receptor signaling pathway
                                                        is-aadrenergic receptor signaling pathway +
                                                        is-aangiotensin-activated signaling pathway +
                                                        is-aapelin receptor signaling pathway
                                                        is-abombesin receptor signaling pathway
                                                        is-acannabinoid signaling pathway +
                                                        is-acholecystokinin signaling pathway +
                                                        is-acomplement component C5a signaling pathway
                                                        is-adimeric G-protein coupled receptor signaling pathway +
                                                        is-adopamine receptor signaling pathway +
                                                        is-aendothelin receptor signaling pathway +
                                                        is-aepidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway
                                                        is-afollicle-stimulating hormone signaling pathway
                                                        is-aG-protein coupled acetylcholine receptor signaling pathway +
                                                        is-aG-protein coupled glutamate receptor signaling pathway +
                                                        is-aG-protein coupled purinergic receptor signaling pathway +
                                                        is-aG-protein coupled receptor signaling in absence of ligand
                                                        is-aG-protein coupled receptor signaling pathway involved in heart process +
                                                        is-aG-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger +
                                                        is-aG-protein coupled receptor signaling pathway, coupled to S1P second messenger
                                                        is-agamma-aminobutyric acid signaling pathway
                                                        is-agastric inhibitory peptide signaling pathway
                                                        part-ofheterotrimeric G-protein complex cycle
                                                        is-aluteinizing hormone signaling pathway +
                                                        negatively-regulatesnegative regulation of G-protein coupled receptor protein signaling pathway +
                                                        is-aneuropeptide signaling pathway
                                                        is-aoctopamine or tyramine signaling pathway +
                                                        is-aopioid receptor signaling pathway +
                                                        is-apheromone-dependent signal transduction involved in conjugation with cellular fusion +
                                                        is-aphospholipase C-activating G-protein coupled receptor signaling pathway [GO:0007200] (59 genes, 81 annotations)
                                                                negatively-regulatesnegative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                is-aphospholipase C-activating adrenergic receptor signaling pathway
                                                                is-aphospholipase C-activating angiotensin-activated signaling pathway +
                                                                is-aphospholipase C-activating dopamine receptor signaling pathway +
                                                                is-aphospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway
                                                                is-aphospholipase C-activating G-protein coupled glutamate receptor signaling pathway
                                                                is-aphospholipase C-activating rhodopsin mediated signaling pathway
                                                                is-aphospholipase C-activating serotonin receptor signaling pathway
                                                                is-aphospholipase C-activating tachykinin receptor signaling pathway
                                                                part-ofpositive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
                                                                positively-regulatespositive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway
                                                                regulatesregulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                        is-aphospholipase C-inhibiting G-protein coupled receptor signaling pathway
                                                        is-aphospholipase D-activating G-protein coupled receptor signaling pathway
                                                        positively-regulatespositive regulation of G-protein coupled receptor protein signaling pathway +
                                                        is-aprotein kinase C-activating G-protein coupled receptor signaling pathway
                                                        regulatesregulation of G-protein coupled receptor protein signaling pathway +
                                                        is-arhodopsin mediated signaling pathway +
                                                        is-aserotonin receptor signaling pathway +
                                                        is-asignal transduction involved in conjugation with mutual genetic exchange
                                                        is-asomatostatin receptor signaling pathway +
                                                        is-asphingosine-1-phosphate signaling pathway +
                                                        is-atachykinin receptor signaling pathway +
                                                        is-athrombin receptor signaling pathway +
                                                        is-athromboxane A2 signaling pathway
                                                        is-athyroid-stimulating hormone signaling pathway


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-acell surface receptor signaling pathway
                                                        is-aG-protein coupled receptor signaling pathway
                                                                is-aadrenergic receptor signaling pathway +
                                                                is-aangiotensin-activated signaling pathway +
                                                                is-aapelin receptor signaling pathway
                                                                is-abombesin receptor signaling pathway
                                                                is-acannabinoid signaling pathway +
                                                                is-acholecystokinin signaling pathway +
                                                                is-acomplement component C5a signaling pathway
                                                                is-adimeric G-protein coupled receptor signaling pathway +
                                                                is-adopamine receptor signaling pathway +
                                                                is-aendothelin receptor signaling pathway +
                                                                is-aepidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway
                                                                is-afollicle-stimulating hormone signaling pathway
                                                                is-aG-protein coupled acetylcholine receptor signaling pathway +
                                                                is-aG-protein coupled glutamate receptor signaling pathway +
                                                                is-aG-protein coupled purinergic receptor signaling pathway +
                                                                is-aG-protein coupled receptor signaling in absence of ligand
                                                                is-aG-protein coupled receptor signaling pathway involved in heart process +
                                                                is-aG-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger +
                                                                is-aG-protein coupled receptor signaling pathway, coupled to S1P second messenger
                                                                is-agamma-aminobutyric acid signaling pathway
                                                                is-agastric inhibitory peptide signaling pathway
                                                                part-ofheterotrimeric G-protein complex cycle
                                                                is-aluteinizing hormone signaling pathway +
                                                                negatively-regulatesnegative regulation of G-protein coupled receptor protein signaling pathway +
                                                                is-aneuropeptide signaling pathway
                                                                is-aoctopamine or tyramine signaling pathway +
                                                                is-aopioid receptor signaling pathway +
                                                                is-apheromone-dependent signal transduction involved in conjugation with cellular fusion +
                                                                is-aphospholipase C-activating G-protein coupled receptor signaling pathway [GO:0007200] (59 genes, 81 annotations)
                                                                        negatively-regulatesnegative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                        is-aphospholipase C-activating adrenergic receptor signaling pathway
                                                                        is-aphospholipase C-activating angiotensin-activated signaling pathway +
                                                                        is-aphospholipase C-activating dopamine receptor signaling pathway +
                                                                        is-aphospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway
                                                                        is-aphospholipase C-activating G-protein coupled glutamate receptor signaling pathway
                                                                        is-aphospholipase C-activating rhodopsin mediated signaling pathway
                                                                        is-aphospholipase C-activating serotonin receptor signaling pathway
                                                                        is-aphospholipase C-activating tachykinin receptor signaling pathway
                                                                        part-ofpositive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
                                                                        positively-regulatespositive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway
                                                                        regulatesregulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                is-aphospholipase C-inhibiting G-protein coupled receptor signaling pathway
                                                                is-aphospholipase D-activating G-protein coupled receptor signaling pathway
                                                                positively-regulatespositive regulation of G-protein coupled receptor protein signaling pathway +
                                                                is-aprotein kinase C-activating G-protein coupled receptor signaling pathway
                                                                regulatesregulation of G-protein coupled receptor protein signaling pathway +
                                                                is-arhodopsin mediated signaling pathway +
                                                                is-aserotonin receptor signaling pathway +
                                                                is-asignal transduction involved in conjugation with mutual genetic exchange
                                                                is-asomatostatin receptor signaling pathway +
                                                                is-asphingosine-1-phosphate signaling pathway +
                                                                is-atachykinin receptor signaling pathway +
                                                                is-athrombin receptor signaling pathway +
                                                                is-athromboxane A2 signaling pathway
                                                                is-athyroid-stimulating hormone signaling pathway


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of cellular process
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aG-protein coupled receptor signaling pathway
                                                        is-aadrenergic receptor signaling pathway +
                                                        is-aangiotensin-activated signaling pathway +
                                                        is-aapelin receptor signaling pathway
                                                        is-abombesin receptor signaling pathway
                                                        is-acannabinoid signaling pathway +
                                                        is-acholecystokinin signaling pathway +
                                                        is-acomplement component C5a signaling pathway
                                                        is-adimeric G-protein coupled receptor signaling pathway +
                                                        is-adopamine receptor signaling pathway +
                                                        is-aendothelin receptor signaling pathway +
                                                        is-aepidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway
                                                        is-afollicle-stimulating hormone signaling pathway
                                                        is-aG-protein coupled acetylcholine receptor signaling pathway +
                                                        is-aG-protein coupled glutamate receptor signaling pathway +
                                                        is-aG-protein coupled purinergic receptor signaling pathway +
                                                        is-aG-protein coupled receptor signaling in absence of ligand
                                                        is-aG-protein coupled receptor signaling pathway involved in heart process +
                                                        is-aG-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger +
                                                        is-aG-protein coupled receptor signaling pathway, coupled to S1P second messenger
                                                        is-agamma-aminobutyric acid signaling pathway
                                                        is-agastric inhibitory peptide signaling pathway
                                                        part-ofheterotrimeric G-protein complex cycle
                                                        is-aluteinizing hormone signaling pathway +
                                                        negatively-regulatesnegative regulation of G-protein coupled receptor protein signaling pathway +
                                                        is-aneuropeptide signaling pathway
                                                        is-aoctopamine or tyramine signaling pathway +
                                                        is-aopioid receptor signaling pathway +
                                                        is-apheromone-dependent signal transduction involved in conjugation with cellular fusion +
                                                        is-aphospholipase C-activating G-protein coupled receptor signaling pathway [GO:0007200] (59 genes, 81 annotations)
                                                                negatively-regulatesnegative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                is-aphospholipase C-activating adrenergic receptor signaling pathway
                                                                is-aphospholipase C-activating angiotensin-activated signaling pathway +
                                                                is-aphospholipase C-activating dopamine receptor signaling pathway +
                                                                is-aphospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway
                                                                is-aphospholipase C-activating G-protein coupled glutamate receptor signaling pathway
                                                                is-aphospholipase C-activating rhodopsin mediated signaling pathway
                                                                is-aphospholipase C-activating serotonin receptor signaling pathway
                                                                is-aphospholipase C-activating tachykinin receptor signaling pathway
                                                                part-ofpositive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
                                                                positively-regulatespositive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway
                                                                regulatesregulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                        is-aphospholipase C-inhibiting G-protein coupled receptor signaling pathway
                                                        is-aphospholipase D-activating G-protein coupled receptor signaling pathway
                                                        positively-regulatespositive regulation of G-protein coupled receptor protein signaling pathway +
                                                        is-aprotein kinase C-activating G-protein coupled receptor signaling pathway
                                                        regulatesregulation of G-protein coupled receptor protein signaling pathway +
                                                        is-arhodopsin mediated signaling pathway +
                                                        is-aserotonin receptor signaling pathway +
                                                        is-asignal transduction involved in conjugation with mutual genetic exchange
                                                        is-asomatostatin receptor signaling pathway +
                                                        is-asphingosine-1-phosphate signaling pathway +
                                                        is-atachykinin receptor signaling pathway +
                                                        is-athrombin receptor signaling pathway +
                                                        is-athromboxane A2 signaling pathway
                                                        is-athyroid-stimulating hormone signaling pathway


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aG-protein coupled receptor signaling pathway
                                                        is-aadrenergic receptor signaling pathway +
                                                        is-aangiotensin-activated signaling pathway +
                                                        is-aapelin receptor signaling pathway
                                                        is-abombesin receptor signaling pathway
                                                        is-acannabinoid signaling pathway +
                                                        is-acholecystokinin signaling pathway +
                                                        is-acomplement component C5a signaling pathway
                                                        is-adimeric G-protein coupled receptor signaling pathway +
                                                        is-adopamine receptor signaling pathway +
                                                        is-aendothelin receptor signaling pathway +
                                                        is-aepidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway
                                                        is-afollicle-stimulating hormone signaling pathway
                                                        is-aG-protein coupled acetylcholine receptor signaling pathway +
                                                        is-aG-protein coupled glutamate receptor signaling pathway +
                                                        is-aG-protein coupled purinergic receptor signaling pathway +
                                                        is-aG-protein coupled receptor signaling in absence of ligand
                                                        is-aG-protein coupled receptor signaling pathway involved in heart process +
                                                        is-aG-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger +
                                                        is-aG-protein coupled receptor signaling pathway, coupled to S1P second messenger
                                                        is-agamma-aminobutyric acid signaling pathway
                                                        is-agastric inhibitory peptide signaling pathway
                                                        part-ofheterotrimeric G-protein complex cycle
                                                        is-aluteinizing hormone signaling pathway +
                                                        negatively-regulatesnegative regulation of G-protein coupled receptor protein signaling pathway +
                                                        is-aneuropeptide signaling pathway
                                                        is-aoctopamine or tyramine signaling pathway +
                                                        is-aopioid receptor signaling pathway +
                                                        is-apheromone-dependent signal transduction involved in conjugation with cellular fusion +
                                                        is-aphospholipase C-activating G-protein coupled receptor signaling pathway [GO:0007200] (59 genes, 81 annotations)
                                                                negatively-regulatesnegative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                is-aphospholipase C-activating adrenergic receptor signaling pathway
                                                                is-aphospholipase C-activating angiotensin-activated signaling pathway +
                                                                is-aphospholipase C-activating dopamine receptor signaling pathway +
                                                                is-aphospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway
                                                                is-aphospholipase C-activating G-protein coupled glutamate receptor signaling pathway
                                                                is-aphospholipase C-activating rhodopsin mediated signaling pathway
                                                                is-aphospholipase C-activating serotonin receptor signaling pathway
                                                                is-aphospholipase C-activating tachykinin receptor signaling pathway
                                                                part-ofpositive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
                                                                positively-regulatespositive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway
                                                                regulatesregulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                        is-aphospholipase C-inhibiting G-protein coupled receptor signaling pathway
                                                        is-aphospholipase D-activating G-protein coupled receptor signaling pathway
                                                        positively-regulatespositive regulation of G-protein coupled receptor protein signaling pathway +
                                                        is-aprotein kinase C-activating G-protein coupled receptor signaling pathway
                                                        regulatesregulation of G-protein coupled receptor protein signaling pathway +
                                                        is-arhodopsin mediated signaling pathway +
                                                        is-aserotonin receptor signaling pathway +
                                                        is-asignal transduction involved in conjugation with mutual genetic exchange
                                                        is-asomatostatin receptor signaling pathway +
                                                        is-asphingosine-1-phosphate signaling pathway +
                                                        is-atachykinin receptor signaling pathway +
                                                        is-athrombin receptor signaling pathway +
                                                        is-athromboxane A2 signaling pathway
                                                        is-athyroid-stimulating hormone signaling pathway


Gene_Ontology
        is-abiological_process
                is-asignaling
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aG-protein coupled receptor signaling pathway
                                                        is-aadrenergic receptor signaling pathway +
                                                        is-aangiotensin-activated signaling pathway +
                                                        is-aapelin receptor signaling pathway
                                                        is-abombesin receptor signaling pathway
                                                        is-acannabinoid signaling pathway +
                                                        is-acholecystokinin signaling pathway +
                                                        is-acomplement component C5a signaling pathway
                                                        is-adimeric G-protein coupled receptor signaling pathway +
                                                        is-adopamine receptor signaling pathway +
                                                        is-aendothelin receptor signaling pathway +
                                                        is-aepidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway
                                                        is-afollicle-stimulating hormone signaling pathway
                                                        is-aG-protein coupled acetylcholine receptor signaling pathway +
                                                        is-aG-protein coupled glutamate receptor signaling pathway +
                                                        is-aG-protein coupled purinergic receptor signaling pathway +
                                                        is-aG-protein coupled receptor signaling in absence of ligand
                                                        is-aG-protein coupled receptor signaling pathway involved in heart process +
                                                        is-aG-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger +
                                                        is-aG-protein coupled receptor signaling pathway, coupled to S1P second messenger
                                                        is-agamma-aminobutyric acid signaling pathway
                                                        is-agastric inhibitory peptide signaling pathway
                                                        part-ofheterotrimeric G-protein complex cycle
                                                        is-aluteinizing hormone signaling pathway +
                                                        negatively-regulatesnegative regulation of G-protein coupled receptor protein signaling pathway +
                                                        is-aneuropeptide signaling pathway
                                                        is-aoctopamine or tyramine signaling pathway +
                                                        is-aopioid receptor signaling pathway +
                                                        is-apheromone-dependent signal transduction involved in conjugation with cellular fusion +
                                                        is-aphospholipase C-activating G-protein coupled receptor signaling pathway [GO:0007200] (59 genes, 81 annotations)
                                                                negatively-regulatesnegative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                is-aphospholipase C-activating adrenergic receptor signaling pathway
                                                                is-aphospholipase C-activating angiotensin-activated signaling pathway +
                                                                is-aphospholipase C-activating dopamine receptor signaling pathway +
                                                                is-aphospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway
                                                                is-aphospholipase C-activating G-protein coupled glutamate receptor signaling pathway
                                                                is-aphospholipase C-activating rhodopsin mediated signaling pathway
                                                                is-aphospholipase C-activating serotonin receptor signaling pathway
                                                                is-aphospholipase C-activating tachykinin receptor signaling pathway
                                                                part-ofpositive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
                                                                positively-regulatespositive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway
                                                                regulatesregulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                        is-aphospholipase C-inhibiting G-protein coupled receptor signaling pathway
                                                        is-aphospholipase D-activating G-protein coupled receptor signaling pathway
                                                        positively-regulatespositive regulation of G-protein coupled receptor protein signaling pathway +
                                                        is-aprotein kinase C-activating G-protein coupled receptor signaling pathway
                                                        regulatesregulation of G-protein coupled receptor protein signaling pathway +
                                                        is-arhodopsin mediated signaling pathway +
                                                        is-aserotonin receptor signaling pathway +
                                                        is-asignal transduction involved in conjugation with mutual genetic exchange
                                                        is-asomatostatin receptor signaling pathway +
                                                        is-asphingosine-1-phosphate signaling pathway +
                                                        is-atachykinin receptor signaling pathway +
                                                        is-athrombin receptor signaling pathway +
                                                        is-athromboxane A2 signaling pathway
                                                        is-athyroid-stimulating hormone signaling pathway


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aG-protein coupled receptor signaling pathway
                                                        is-aadrenergic receptor signaling pathway +
                                                        is-aangiotensin-activated signaling pathway +
                                                        is-aapelin receptor signaling pathway
                                                        is-abombesin receptor signaling pathway
                                                        is-acannabinoid signaling pathway +
                                                        is-acholecystokinin signaling pathway +
                                                        is-acomplement component C5a signaling pathway
                                                        is-adimeric G-protein coupled receptor signaling pathway +
                                                        is-adopamine receptor signaling pathway +
                                                        is-aendothelin receptor signaling pathway +
                                                        is-aepidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway
                                                        is-afollicle-stimulating hormone signaling pathway
                                                        is-aG-protein coupled acetylcholine receptor signaling pathway +
                                                        is-aG-protein coupled glutamate receptor signaling pathway +
                                                        is-aG-protein coupled purinergic receptor signaling pathway +
                                                        is-aG-protein coupled receptor signaling in absence of ligand
                                                        is-aG-protein coupled receptor signaling pathway involved in heart process +
                                                        is-aG-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger +
                                                        is-aG-protein coupled receptor signaling pathway, coupled to S1P second messenger
                                                        is-agamma-aminobutyric acid signaling pathway
                                                        is-agastric inhibitory peptide signaling pathway
                                                        part-ofheterotrimeric G-protein complex cycle
                                                        is-aluteinizing hormone signaling pathway +
                                                        negatively-regulatesnegative regulation of G-protein coupled receptor protein signaling pathway +
                                                        is-aneuropeptide signaling pathway
                                                        is-aoctopamine or tyramine signaling pathway +
                                                        is-aopioid receptor signaling pathway +
                                                        is-apheromone-dependent signal transduction involved in conjugation with cellular fusion +
                                                        is-aphospholipase C-activating G-protein coupled receptor signaling pathway [GO:0007200] (59 genes, 81 annotations)
                                                                negatively-regulatesnegative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                is-aphospholipase C-activating adrenergic receptor signaling pathway
                                                                is-aphospholipase C-activating angiotensin-activated signaling pathway +
                                                                is-aphospholipase C-activating dopamine receptor signaling pathway +
                                                                is-aphospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway
                                                                is-aphospholipase C-activating G-protein coupled glutamate receptor signaling pathway
                                                                is-aphospholipase C-activating rhodopsin mediated signaling pathway
                                                                is-aphospholipase C-activating serotonin receptor signaling pathway
                                                                is-aphospholipase C-activating tachykinin receptor signaling pathway
                                                                part-ofpositive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
                                                                positively-regulatespositive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway
                                                                regulatesregulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                        is-aphospholipase C-inhibiting G-protein coupled receptor signaling pathway
                                                        is-aphospholipase D-activating G-protein coupled receptor signaling pathway
                                                        positively-regulatespositive regulation of G-protein coupled receptor protein signaling pathway +
                                                        is-aprotein kinase C-activating G-protein coupled receptor signaling pathway
                                                        regulatesregulation of G-protein coupled receptor protein signaling pathway +
                                                        is-arhodopsin mediated signaling pathway +
                                                        is-aserotonin receptor signaling pathway +
                                                        is-asignal transduction involved in conjugation with mutual genetic exchange
                                                        is-asomatostatin receptor signaling pathway +
                                                        is-asphingosine-1-phosphate signaling pathway +
                                                        is-atachykinin receptor signaling pathway +
                                                        is-athrombin receptor signaling pathway +
                                                        is-athromboxane A2 signaling pathway
                                                        is-athyroid-stimulating hormone signaling pathway


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-acell surface receptor signaling pathway
                                                        is-aG-protein coupled receptor signaling pathway
                                                                is-aadrenergic receptor signaling pathway +
                                                                is-aangiotensin-activated signaling pathway +
                                                                is-aapelin receptor signaling pathway
                                                                is-abombesin receptor signaling pathway
                                                                is-acannabinoid signaling pathway +
                                                                is-acholecystokinin signaling pathway +
                                                                is-acomplement component C5a signaling pathway
                                                                is-adimeric G-protein coupled receptor signaling pathway +
                                                                is-adopamine receptor signaling pathway +
                                                                is-aendothelin receptor signaling pathway +
                                                                is-aepidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway
                                                                is-afollicle-stimulating hormone signaling pathway
                                                                is-aG-protein coupled acetylcholine receptor signaling pathway +
                                                                is-aG-protein coupled glutamate receptor signaling pathway +
                                                                is-aG-protein coupled purinergic receptor signaling pathway +
                                                                is-aG-protein coupled receptor signaling in absence of ligand
                                                                is-aG-protein coupled receptor signaling pathway involved in heart process +
                                                                is-aG-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger +
                                                                is-aG-protein coupled receptor signaling pathway, coupled to S1P second messenger
                                                                is-agamma-aminobutyric acid signaling pathway
                                                                is-agastric inhibitory peptide signaling pathway
                                                                part-ofheterotrimeric G-protein complex cycle
                                                                is-aluteinizing hormone signaling pathway +
                                                                negatively-regulatesnegative regulation of G-protein coupled receptor protein signaling pathway +
                                                                is-aneuropeptide signaling pathway
                                                                is-aoctopamine or tyramine signaling pathway +
                                                                is-aopioid receptor signaling pathway +
                                                                is-apheromone-dependent signal transduction involved in conjugation with cellular fusion +
                                                                is-aphospholipase C-activating G-protein coupled receptor signaling pathway [GO:0007200] (59 genes, 81 annotations)
                                                                        negatively-regulatesnegative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                        is-aphospholipase C-activating adrenergic receptor signaling pathway
                                                                        is-aphospholipase C-activating angiotensin-activated signaling pathway +
                                                                        is-aphospholipase C-activating dopamine receptor signaling pathway +
                                                                        is-aphospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway
                                                                        is-aphospholipase C-activating G-protein coupled glutamate receptor signaling pathway
                                                                        is-aphospholipase C-activating rhodopsin mediated signaling pathway
                                                                        is-aphospholipase C-activating serotonin receptor signaling pathway
                                                                        is-aphospholipase C-activating tachykinin receptor signaling pathway
                                                                        part-ofpositive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
                                                                        positively-regulatespositive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway
                                                                        regulatesregulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                is-aphospholipase C-inhibiting G-protein coupled receptor signaling pathway
                                                                is-aphospholipase D-activating G-protein coupled receptor signaling pathway
                                                                positively-regulatespositive regulation of G-protein coupled receptor protein signaling pathway +
                                                                is-aprotein kinase C-activating G-protein coupled receptor signaling pathway
                                                                regulatesregulation of G-protein coupled receptor protein signaling pathway +
                                                                is-arhodopsin mediated signaling pathway +
                                                                is-aserotonin receptor signaling pathway +
                                                                is-asignal transduction involved in conjugation with mutual genetic exchange
                                                                is-asomatostatin receptor signaling pathway +
                                                                is-asphingosine-1-phosphate signaling pathway +
                                                                is-atachykinin receptor signaling pathway +
                                                                is-athrombin receptor signaling pathway +
                                                                is-athromboxane A2 signaling pathway
                                                                is-athyroid-stimulating hormone signaling pathway


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory