| GO term: | phospholipase C-activating G-protein coupled receptor signaling pathway |
| Synonym: | activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger |
| Synonym: | G-protein coupled receptor signaling pathway coupled to IP3 second messenger |
| Synonym: | G protein signaling, coupled to IP3 second messenger (phospholipase C activating) |
| Synonym: | G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) |
| Synonym: | G protein signalling, coupled to IP3 second messenger (phospholipase C activating) |
| Synonym: | G-protein signalling, coupled to IP3 second messenger (phospholipase C activating) |
| Synonym: | phospholipase C-activating dopamine receptor signaling pathway |
| Synonym: | PLC-activating GPCR signaling pathway |
| GO id: | GO:0007200 |
| Definition: | The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent increase in the concentration of inositol trisphosphate (IP3) and diacylglycerol (DAG). |
| Comments | This term is intended to cover steps in a GPCR signaling pathway both upstream and downstream of phospholipase C (PLC) activity. |
| Number of paths to term: | 10 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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