| GO term: | hormone activity |
| Synonym: | cAMP generating peptide activity |
| Synonym: | glycopeptide hormone |
| Synonym: | lipopeptide hormone |
| Synonym: | peptide hormone |
| GO id: | GO:0005179 |
| Definition: | The action characteristic of a hormone, any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. The term was originally applied to agents with a stimulatory physiological action in vertebrate animals (as opposed to a chalone, which has a depressant action). Usage is now extended to regulatory compounds in lower animals and plants, and to synthetic substances having comparable effects; all bind receptors and trigger some biological process. |
| Number of paths to term: | 1 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
molecular_functionbindingprotein bindingreceptor bindingacetylcholine receptor bindingapolipoprotein receptor binding +aryl hydrocarbon receptor bindingbenzodiazepine receptor bindingCD154 receptor bindingCD4 receptor bindingCD70 receptor bindingCD8 receptor bindingcytokine activity +cytokine receptor binding +ephrin receptor bindingErbB-2 class receptor bindingErbB-3 class receptor bindingG-protein coupled receptor binding +GABA receptor binding +glutamate receptor binding +growth factor activitygrowth factor receptor binding +high molecular weight kininogen receptor bindinghormone activity [GO:0005179] (118 genes, 145 annotations)corticotropin-releasing hormone activitydigestive hormone activitydiuretic hormone activityfollicle-stimulating hormone activitygonadotropin hormone-releasing hormone activitygrowth hormone activitygrowth hormone-releasing hormone activitymelanin-concentrating hormone activitymelanocyte-stimulating hormone activitymyoinhibitory hormone activitymyostimulatory hormone activityneuropeptide hormone activity +pituitary adenylate cyclase activating polypeptide activitythyrotropin-releasing hormone activityhormone receptor binding +host cell surface receptor bindingimmunoglobulin receptor binding +insulin receptor bindinginsulin-like growth factor receptor bindingintegrin bindingintercellular adhesion molecule-3 receptor bindingligand-dependent nuclear receptor bindinglipoprotein particle receptor binding +MDA-5 bindingMHC protein binding +natural killer cell lectin-like receptor bindingNotch bindingopioid peptide activitypatched bindingperoxisome proliferator activated receptor bindingpheromone activity +RAGE receptor bindingreceptor agonist activity +receptor antagonist activity +receptor serine/threonine kinase binding +receptor tyrosine kinase binding +receptor tyrosine kinase-like orphan receptor bindingRIG-I bindingRoundabout bindingscavenger receptor bindingsemaphorin receptor bindingsevenless bindingsmoothened bindingsulfonylurea receptor bindingT cell receptor bindingToll bindingToll-like receptor binding +torso bindingtoxin receptor bindingwishful thinking bindingMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/22/2013 MGI 5.13 |
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