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Gene Ontology Browser
Term Detail
GO term:hormone activity
Synonym: cAMP generating peptide activity
Synonym: glycopeptide hormone
Synonym: lipopeptide hormone
Synonym: peptide hormone
GO id:GO:0005179
Definition:The action characteristic of a hormone, any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. The term was originally applied to agents with a stimulatory physiological action in vertebrate animals (as opposed to a chalone, which has a depressant action). Usage is now extended to regulatory compounds in lower animals and plants, and to synthetic substances having comparable effects; all bind receptors and trigger some biological process.
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-amolecular_function
                is-abinding
                        is-aprotein binding
                                is-areceptor binding
                                        is-aacetylcholine receptor binding
                                        is-aapolipoprotein receptor binding +
                                        is-aaryl hydrocarbon receptor binding
                                        is-abenzodiazepine receptor binding
                                        is-aCD154 receptor binding
                                        is-aCD4 receptor binding
                                        is-aCD70 receptor binding
                                        is-aCD8 receptor binding
                                        is-acytokine activity +
                                        is-acytokine receptor binding +
                                        is-aephrin receptor binding
                                        is-aErbB-2 class receptor binding
                                        is-aErbB-3 class receptor binding
                                        is-aG-protein coupled receptor binding +
                                        is-aGABA receptor binding +
                                        is-aglutamate receptor binding +
                                        is-agrowth factor activity
                                        is-agrowth factor receptor binding +
                                        is-ahigh molecular weight kininogen receptor binding
                                        is-ahormone activity [GO:0005179] (125 genes, 157 annotations)
                                                is-acorticotropin-releasing hormone activity
                                                is-adigestive hormone activity
                                                is-adiuretic hormone activity
                                                is-afollicle-stimulating hormone activity
                                                is-agonadotropin hormone-releasing hormone activity
                                                is-agrowth hormone activity
                                                is-agrowth hormone-releasing hormone activity
                                                is-amelanin-concentrating hormone activity
                                                is-amelanocyte-stimulating hormone activity
                                                is-amyoinhibitory hormone activity
                                                is-amyostimulatory hormone activity
                                                is-aneuropeptide hormone activity +
                                                is-apituitary adenylate cyclase activating polypeptide activity
                                                is-athyrotropin-releasing hormone activity
                                        is-ahormone receptor binding +
                                        is-ahost cell surface receptor binding
                                        is-aimmunoglobulin receptor binding +
                                        is-ainsulin receptor binding
                                        is-ainsulin-like growth factor receptor binding
                                        is-aintegrin binding +
                                        is-aintercellular adhesion molecule-3 receptor binding
                                        is-aleptin receptor binding
                                        is-aligand-dependent nuclear receptor binding
                                        is-alipoprotein particle receptor binding +
                                        is-aMDA-5 binding
                                        is-aMHC protein binding +
                                        is-anatural killer cell lectin-like receptor binding
                                        is-aneuropilin binding
                                        is-aNotch binding
                                        is-aopioid peptide activity
                                        is-apatched binding
                                        is-aperoxisome proliferator activated receptor binding
                                        is-apheromone activity +
                                        is-aRAGE receptor binding
                                        is-areceptor agonist activity +
                                        is-areceptor antagonist activity +
                                        is-areceptor serine/threonine kinase binding +
                                        is-areceptor tyrosine kinase binding +
                                        is-areceptor tyrosine kinase-like orphan receptor binding
                                        is-aRIG-I binding
                                        is-aRoundabout binding
                                        is-ascavenger receptor binding
                                        is-asemaphorin receptor binding
                                        is-asevenless binding
                                        is-asmoothened binding
                                        is-asulfonylurea receptor binding
                                        is-aT cell receptor binding
                                        is-aToll binding
                                        is-aToll-like receptor binding +
                                        is-atorso binding
                                        is-atoxin receptor binding
                                        is-atransferrin receptor binding
                                        is-awishful thinking binding


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/16/2014
MGI 5.19
The Jackson Laboratory