Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes USP16
  • Mouse genes Usp16
  • Rat genes Usp16
  • Zfish genes usp16
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Usp16

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP16	IDA		Human	PMID:17914355
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	USP16	IMP		Human	PMID:17914355
Molecular Function	GO:0042393	histone binding	USP16	IDA		Human	PMID:17914355
Molecular Function	GO:0140950	histone H2A deubiquitinase activity	USP16	IMP		Human	PMID:20550933
Molecular Function	GO:0140950	histone H2A deubiquitinase activity	Usp16	IMP		Mouse	MGI:MGI:5527017|PMID:24034696
Molecular Function	GO:0005515	protein binding	Usp16	IPI	UniProtKB:O70126	Mouse	MGI:MGI:5527017|PMID:24034696
Molecular Function	GO:0003713	transcription coactivator activity	USP16	IDA		Human	PMID:17914355
Molecular Function	GO:0043130	ubiquitin binding	USP16	IDA		Human	PMID:17512543
Molecular Function	GO:0008270	zinc ion binding	USP16	IDA		Human	PMID:17512543
Cellular Component	GO:0005634	nucleus	USP16	IDA		Human	PMID:17914355
Biological Process	GO:0006974	DNA damage response	USP16	IDA		Human	PMID:20550933
Biological Process	GO:0000278	mitotic cell cycle	USP16	IDA		Human	PMID:17914355
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	USP16	IMP		Human	PMID:17914355
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Usp16	IMP		Mouse	MGI:MGI:5527017|PMID:24034696
Biological Process	GO:0045901	positive regulation of translational elongation	USP16	IMP		Human	PMID:20550933
Biological Process	GO:0051289	protein homotetramerization	USP16	IPI	UniProtKB:Q9Y5T5	Human	PMID:17914355
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Usp16	IDA		Mouse	MGI:MGI:5527017|PMID:24034696

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern