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Term Detail
GO term:histone binding
Synonym: histone-specific chaperone activity
GO id:GO:0042393
Definition:Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship

                        is-aprotein binding
                                is-a14-3-3 protein binding
                                is-aadiponectin binding
                                is-aalpha-catenin binding
                                is-aangiostatin binding
                                is-aantisigma factor binding
                                is-aapolipoprotein binding +
                                is-aATP-dependent protein binding
                                is-abasal transcription machinery binding +
                                is-abeta-2-microglobulin binding
                                is-abeta-catenin binding
                                is-abone sialoprotein binding
                                is-acalcium-dependent protein binding
                                is-acalmodulin binding
                                is-acell adhesion molecule binding +
                                is-achaperone binding
                                is-aclathrin binding +
                                is-aco-receptor binding
                                is-acomplement binding +
                                is-aconnexin binding
                                is-acopper-dependent protein binding
                                is-acullin family protein binding
                                is-acyclin binding
                                is-acytokine binding +
                                is-acytoskeletal protein binding +
                                is-adelta-catenin binding
                                is-adenatured protein binding
                                is-adynein binding +
                                is-aendocytic targeting sequence binding
                                is-aenzyme binding +
                                is-aextracellular matrix protein binding
                                is-afarnesylated protein binding
                                is-afibronectin binding
                                is-aG-protein alpha-subunit binding
                                is-aG-protein beta-subunit binding
                                is-aG-protein gamma-subunit binding
                                is-agamma-catenin binding
                                is-aGDP-dissociation inhibitor binding +
                                is-aglycoprotein binding +
                                is-agrowth factor binding +
                                is-aGTP-dependent protein binding
                                is-aGTPase activating protein binding
                                is-ahaptoglobin binding
                                is-aheat shock protein binding +
                                is-ahedgehog family protein binding
                                is-ahemoglobin binding +
                                is-ahexon binding
                                is-ahistone binding [GO:0042393] (120 genes, 146 annotations)
                                        is-alysine-acetylated histone binding
                                        is-amethylated histone binding +
                                        is-anucleosomal histone binding
                                is-aidentical protein binding +
                                is-ainhibin binding
                                is-ainsulin receptor substrate binding
                                is-aion channel binding
                                is-akininogen binding +
                                is-alamin binding
                                is-alaminin binding +
                                is-aMDM2/MDM4 family protein binding
                                is-amisfolded protein binding
                                is-aneurexin family protein binding
                                is-aneuroligin family protein binding
                                is-anodal binding
                                is-aopsin binding
                                is-aopsonin binding +
                                is-ap53 binding
                                is-aphosphatidylinositol 3-kinase binding +
                                is-aphosphoprotein binding +
                                is-aphytochrome binding
                                is-apoly-glutamine tract binding
                                is-apreprotein binding
                                is-aprofilin binding
                                is-aproline-rich region binding +
                                is-aprotein anchor
                                is-aprotein antigen binding
                                is-aprotein binding involved in cell adhesion +
                                is-aprotein binding involved in cell-cell adhesion +
                                is-aprotein binding involved in cell-matrix adhesion +
                                is-aprotein binding involved in heterotypic cell-cell adhesion +
                                is-aprotein binding involved in negative regulation of telomere maintenance via telomerase
                                is-aprotein binding involved in protein folding
                                is-aprotein binding, bridging +
                                is-aprotein C-terminus binding
                                is-aprotein complex binding +
                                is-aprotein complex scaffold +
                                is-aprotein dimerization activity +
                                is-aprotein domain specific binding +
                                is-aprotein kinase A binding +
                                is-aprotein N-terminus binding +
                                is-aprotein self-association +
                                is-areceptor binding +
                                is-aS100 protein binding
                                is-ascaffold protein binding
                                is-aserpin family protein binding
                                is-aSMAD binding +
                                is-asmall conjugating protein binding +
                                is-aSMC family protein binding
                                is-aSNAP receptor activity
                                is-aSNARE binding +
                                is-asoluble NSF attachment protein activity
                                is-asterol-dependent protein binding
                                is-asyndecan binding
                                is-aTAP binding +
                                is-atapasin binding
                                is-atoxin-antitoxin pair type II binding
                                is-aTRAIL binding
                                is-atranscription factor binding +
                                is-atranslation initiation factor binding +
                                is-aunfolded protein binding
                                is-avery-low-density lipoprotein particle binding
                                is-aWnt-protein binding
                                is-aX11-like protein binding

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 5.20
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