Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes USF2
  • Mouse genes Usf2
  • Rat genes Usf2
  • Zfish genes usf2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Usf2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043425	bHLH transcription factor binding	USF2	IPI	UniProtKB:P22415	Human	PMID:8576131
Molecular Function	GO:0003677	DNA binding	Usf2	IDA		Mouse	PMID:7523363
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Usf2	IMP		Rat	PMID:17408383|RGD:1626707
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	USF2	IMP		Human	PMID:8576131
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Usf2	IDA		Rat	PMID:17408383|RGD:1626707
Molecular Function	GO:0003690	double-stranded DNA binding	Usf2	IDA		Rat	PMID:17408383|RGD:1626707
Molecular Function	GO:0042802	identical protein binding	Usf2	IMP		Rat	PMID:8576131|RGD:634234
Molecular Function	GO:0005515	protein binding	USF2	IPI	UniProtKB:Q01664	Human	PMID:19505873
Molecular Function	GO:0005515	protein binding	USF2	IPI	UniProtKB:Q15562	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	USF2	IPI	UniProtKB:Q6FG41	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	USF2	IPI	UniProtKB:Q9BRK4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	Usf2	IPI	UniProtKB:P42225	Mouse	MGI:MGI:5495054|PMID:23749757
Molecular Function	GO:0046982	protein heterodimerization activity	USF2	IPI	UniProtKB:P22415	Human	PMID:8576131
Molecular Function	GO:0042803	protein homodimerization activity	USF2	IPI	UniProtKB:Q15853	Human	PMID:8576131
Molecular Function	GO:0044877	protein-containing complex binding	Usf2	IMP		Rat	PMID:8576131|RGD:634234
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Usf2	IDA		Rat	PMID:8576131|RGD:634234
Molecular Function	GO:0043565	sequence-specific DNA binding	USF2	IDA		Human	PMID:8576131
Molecular Function	GO:0043565	sequence-specific DNA binding	Usf2	IDA		Rat	PMID:17408383|RGD:1626707
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	USF2	IDA		Human	PMID:28473536
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	USF2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	USF2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	USF2	IDA		Human	PMID:15358760
Cellular Component	GO:0005634	nucleus	USF2	IDA		Human	PMID:8576131
Cellular Component	GO:0005634	nucleus	Usf2	IDA		Mouse	PMID:15661922
Cellular Component	GO:0005634	nucleus	Usf2	IDA		Mouse	PMID:12907752
Cellular Component	GO:0005634	nucleus	Usf2	IDA		Rat	PMID:17408383|RGD:1626707
Biological Process	GO:0007595	lactation	Usf2	IMP	MGI:MGI:2181680	Mouse	PMID:12907752
Biological Process	GO:0055088	lipid homeostasis	Usf2	IMP		Mouse	MGI:MGI:1330677|PMID:9890958
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Usf2	IDA		Mouse	PMID:15466854
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	USF2	IMP		Human	PMID:8576131
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Usf2	IMP		Rat	PMID:17408383|RGD:1626707
Biological Process	GO:0000432	positive regulation of transcription from RNA polymerase II promoter by glucose	USF2	IMP		Human	PMID:7852331
Biological Process	GO:0000432	positive regulation of transcription from RNA polymerase II promoter by glucose	Usf2	IMP		Mouse	MGI:MGI:1330677|PMID:9890958
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Usf2	IDA		Mouse	PMID:7523363

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern