Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Traf3ip2

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes TRAF3IP2
- Mouse genes Traf3ip2
- Rat genes Traf3ip2
- Zfish genes traf3ip2a,traf3ip2b,traf3ip2l
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Traf3ip2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TRAF3IP2	IPI	UniProtKB:Q9Y4K3	Human	PMID:12459498
Molecular Function	GO:0005515	protein binding	TRAF3IP2	IPI	UniProtKB:Q9Y4K3	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	TRAF3IP2	IPI	UniProtKB:Q8NAC3	Human	PMID:24120361
Molecular Function	GO:0005515	protein binding	TRAF3IP2	IPI	UniProtKB:Q96F46	Human	PMID:24120361
Molecular Function	GO:0005515	protein binding	TRAF3IP2	IPI	UniProtKB:Q9NRM6	Human	PMID:24120361
Molecular Function	GO:0005515	protein binding	TRAF3IP2	IPI	UniProtKB:O75716	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF3IP2	IPI	UniProtKB:Q13084	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF3IP2	IPI	UniProtKB:Q15654	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF3IP2	IPI	UniProtKB:Q96C98	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF3IP2	IPI	UniProtKB:Q9UFD9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF3IP2	IPI	UniProtKB:Q9Y4K3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	Traf3ip2	IPI	UniProtKB:P70196	Mouse	MGI:MGI:3688344\|PMID:15102471
Molecular Function	GO:0005515	protein binding	Traf3ip2	IPI	UniProtKB:Q60943	Mouse	MGI:MGI:6694386\|PMID:33723527
Molecular Function	GO:0005515	protein binding	Traf3ip2	IPI	UniProtKB:Q3U564	Mouse	PMID:29563620
Molecular Function	GO:0005515	protein binding	Traf3ip2	IPI	UniProtKB:P70191	Mouse	PMID:21822258
Molecular Function	GO:0005515	protein binding	Traf3ip2	IPI	UniProtKB:Q01705	Mouse	PMID:28561022
Molecular Function	GO:0005515	protein binding	Traf3ip2	IPI	UniProtKB:Q6PDM2	Mouse	PMID:29563620
Molecular Function	GO:0005515	protein binding	Traf3ip2	IPI	UniProtKB:Q6PDM2	Mouse	PMID:21822258
Molecular Function	GO:0005515	protein binding	Traf3ip2	IPI	UniProtKB:Q9JIP3	Mouse	PMID:19155511
Molecular Function	GO:0005515	protein binding	Traf3ip2	IPI	UniProtKB:Q8BH06	Mouse	PMID:19155512
Molecular Function	GO:0005515	protein binding	Traf3ip2	IPI	UniProtKB:P70372	Mouse	PMID:29563620
Molecular Function	GO:0005515	protein binding	Traf3ip2	IPI	UniProtKB:Q9R0T8	Mouse	PMID:21822257
Molecular Function	GO:0005102	signaling receptor binding	Traf3ip2	IPI	UniProtKB:Q8K4C2	Mouse	MGI:MGI:4462077\|PMID:20554964
Molecular Function	GO:0061630	ubiquitin protein ligase activity	TRAF3IP2	IDA		Human	PMID:19825828
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Traf3ip2	IDA		Mouse	PMID:19825828
Molecular Function	GO:0031625	ubiquitin protein ligase binding	traf3ip2b	IDA		Zfish	PMID:21643828
Cellular Component	GO:0031410	cytoplasmic vesicle	Traf3ip2	IPI	UniProtKB:P70372	Mouse	PMID:29563620
Cellular Component	GO:0005634	nucleus	Traf3ip2	IPI	UniProtKB:Q6PDM2	Mouse	PMID:29563620
Biological Process	GO:0002344	B cell affinity maturation	Traf3ip2	IMP	MGI:MGI:3510784	Mouse	PMID:20543113
Biological Process	GO:0001783	B cell apoptotic process	Traf3ip2	IMP	MGI:MGI:3510784	Mouse	PMID:15485634
Biological Process	GO:0001782	B cell homeostasis	Traf3ip2	IMP	MGI:MGI:3510784	Mouse	PMID:20543113
Biological Process	GO:0019724	B cell mediated immunity	Traf3ip2	IGI	MGI:MGI:88336	Mouse	PMID:18624351
Biological Process	GO:0019724	B cell mediated immunity	Traf3ip2	IGI	MGI:MGI:2143599	Mouse	PMID:18624351
Biological Process	GO:0023035	CD40 signaling pathway	Traf3ip2	IGI	MGI:MGI:88336	Mouse	PMID:18624351
Biological Process	GO:0071345	cellular response to cytokine stimulus	Traf3ip2	IMP	MGI:MGI:3510784	Mouse	PMID:21856933
Biological Process	GO:0097398	cellular response to interleukin-17	Traf3ip2	IDA		Mouse	PMID:29563620
Biological Process	GO:0002367	cytokine production involved in immune response	Traf3ip2	IMP	MGI:MGI:3510784	Mouse	PMID:21856933
Biological Process	GO:0002534	cytokine production involved in inflammatory response	Traf3ip2	IMP	MGI:MGI:3510784	Mouse	PMID:21856933
Biological Process	GO:0019221	cytokine-mediated signaling pathway	Traf3ip2	IMP	MGI:MGI:3831153	Mouse	PMID:19155511
Biological Process	GO:0051607	defense response to virus	traf3ip2b	IDA		Zfish	PMID:23066157
Biological Process	GO:1990959	eosinophil homeostasis	Traf3ip2	IMP	MGI:MGI:3510784	Mouse	PMID:19155512
Biological Process	GO:0002447	eosinophil mediated immunity	Traf3ip2	IMP	MGI:MGI:3831153	Mouse	PMID:19155511
Biological Process	GO:0001768	establishment of T cell polarity	Traf3ip2	IMP	MGI:MGI:3510784	Mouse	PMID:21856933
Biological Process	GO:0010467	gene expression	Traf3ip2	IMP	MGI:MGI:3510784	Mouse	PMID:19825828
Biological Process	GO:0010467	gene expression	Traf3ip2	IMP	MGI:MGI:3510784	Mouse	PMID:21856933
Biological Process	GO:0010467	gene expression	Traf3ip2	IMP	MGI:MGI:3510784	Mouse	PMID:19155512
Biological Process	GO:0010467	gene expression	Traf3ip2	IMP	MGI:MGI:3831153	Mouse	PMID:19155511
Biological Process	GO:0010467	gene expression	Traf3ip2	IDA		Mouse	PMID:28561022
Biological Process	GO:0010467	gene expression	Traf3ip2	IMP	MGI:MGI:3707541	Mouse	PMID:21822257
Biological Process	GO:0007507	heart development	Traf3ip2	IDA		Mouse	PMID:27466370
Biological Process	GO:0006959	humoral immune response	Traf3ip2	IMP	MGI:MGI:3510784	Mouse	PMID:15485634
Biological Process	GO:0006955	immune response	Traf3ip2	IMP	MGI:MGI:3510784	Mouse	PMID:23995070
Biological Process	GO:0006955	immune response	Traf3ip2	IMP	MGI:MGI:4820827	Mouse	PMID:20660351
Biological Process	GO:0006955	immune response	Traf3ip2	IMP	MGI:MGI:3707541	Mouse	PMID:21822257
Biological Process	GO:0002377	immunoglobulin production	Traf3ip2	IGI	MGI:MGI:2143599	Mouse	PMID:18624351
Biological Process	GO:0002377	immunoglobulin production	Traf3ip2	IGI	MGI:MGI:88336	Mouse	PMID:18624351
Biological Process	GO:0002377	immunoglobulin production	Traf3ip2	IMP	MGI:MGI:3510784	Mouse	PMID:22585710
Biological Process	GO:0002377	immunoglobulin production	Traf3ip2	IMP	MGI:MGI:3510784	Mouse	PMID:21856933
Biological Process	GO:0002377	immunoglobulin production	Traf3ip2	IMP	MGI:MGI:3510784	Mouse	PMID:15485634
Biological Process	GO:0006954	inflammatory response	TRAF3IP2	IDA		Human	PMID:17277779
Biological Process	GO:0006954	inflammatory response	Traf3ip2	IMP	MGI:MGI:3510784	Mouse	PMID:19155512
Biological Process	GO:0006954	inflammatory response	Traf3ip2	IMP	MGI:MGI:3510784	Mouse	PMID:17277779
Biological Process	GO:0006954	inflammatory response	Traf3ip2	IMP	MGI:MGI:3510784	Mouse	PMID:20303295
Biological Process	GO:0006954	inflammatory response	Traf3ip2	IMP	MGI:MGI:3510784	Mouse	PMID:21856933
Biological Process	GO:0006954	inflammatory response	Traf3ip2	IDA		Mouse	PMID:17277779
Biological Process	GO:0006954	inflammatory response	Traf3ip2	IMP	MGI:MGI:3510784	Mouse	PMID:18624351
Biological Process	GO:0097400	interleukin-17-mediated signaling pathway	TRAF3IP2	IMP		Human	PMID:19825828
Biological Process	GO:0097400	interleukin-17-mediated signaling pathway	TRAF3IP2	IMP		Human	PMID:24120361
Biological Process	GO:0097400	interleukin-17-mediated signaling pathway	Traf3ip2	IMP	MGI:MGI:4820827	Mouse	PMID:20660351
Biological Process	GO:0097400	interleukin-17-mediated signaling pathway	Traf3ip2	IMP	MGI:MGI:3510784	Mouse	PMID:19155512
Biological Process	GO:0097400	interleukin-17-mediated signaling pathway	Traf3ip2	IDA		Mouse	PMID:21822257
Biological Process	GO:0097400	interleukin-17-mediated signaling pathway	Traf3ip2	IDA		Mouse	PMID:21822258
Biological Process	GO:0097400	interleukin-17-mediated signaling pathway	Traf3ip2	IDA		Mouse	PMID:19825828
Biological Process	GO:0097400	interleukin-17-mediated signaling pathway	Traf3ip2	IDA		Mouse	PMID:28561022
Biological Process	GO:0097400	interleukin-17-mediated signaling pathway	Traf3ip2	IMP	MGI:MGI:3510784	Mouse	PMID:23995070
Biological Process	GO:0097400	interleukin-17-mediated signaling pathway	Traf3ip2	IMP	MGI:MGI:3510784	Mouse	PMID:20303295
Biological Process	GO:0097400	interleukin-17-mediated signaling pathway	Traf3ip2	IMP	MGI:MGI:3510784	Mouse	PMID:19825828
Biological Process	GO:0038173	interleukin-17A-mediated signaling pathway	TRAF3IP2	IDA		Human	PMID:17277779
Biological Process	GO:0038173	interleukin-17A-mediated signaling pathway	TRAF3IP2	IDA		Human	PMID:19825828
Biological Process	GO:0038173	interleukin-17A-mediated signaling pathway	Traf3ip2	IMP	MGI:MGI:3831153	Mouse	PMID:19155511
Biological Process	GO:0038173	interleukin-17A-mediated signaling pathway	Traf3ip2	IDA		Mouse	PMID:17277779
Biological Process	GO:0038173	interleukin-17A-mediated signaling pathway	Traf3ip2	IMP	MGI:MGI:3510784	Mouse	PMID:17277779
Biological Process	GO:0001822	kidney development	Traf3ip2	IMP	MGI:MGI:3510784	Mouse	PMID:22585710
Biological Process	GO:0002269	leukocyte activation involved in inflammatory response	Traf3ip2	IMP	MGI:MGI:3510784	Mouse	PMID:20303295
Biological Process	GO:0048535	lymph node development	Traf3ip2	IMP	MGI:MGI:3510784	Mouse	PMID:22585710
Biological Process	GO:0048255	mRNA stabilization	Traf3ip2	IMP		Mouse	PMID:21822258
Biological Process	GO:0048255	mRNA stabilization	Traf3ip2	IDA		Mouse	PMID:17785852
Biological Process	GO:0070254	mucus secretion	Traf3ip2	IMP	MGI:MGI:3831153	Mouse	PMID:19155511
Biological Process	GO:0042119	neutrophil activation	Traf3ip2	IMP	MGI:MGI:3510784	Mouse	PMID:19155512
Biological Process	GO:0002230	positive regulation of defense response to virus by host	TRAF3IP2	IDA		Human	PMID:23066157
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	TRAF3IP2	IEP		Human	PMID:12761501
Biological Process	GO:0006606	protein import into nucleus	Traf3ip2	IDA		Mouse	PMID:28561022
Biological Process	GO:0070534	protein K63-linked ubiquitination	TRAF3IP2	IDA		Human	PMID:19825828
Biological Process	GO:0034504	protein localization to nucleus	Traf3ip2	IDA		Mouse	PMID:29563620
Biological Process	GO:0110012	protein localization to P-body	Traf3ip2	IDA		Mouse	PMID:29563620
Biological Process	GO:0000209	protein polyubiquitination	Traf3ip2	IMP		Mouse	PMID:19825828
Biological Process	GO:0016567	protein ubiquitination	Traf3ip2	IMP	MGI:MGI:4011845	Mouse	PMID:23042150
Biological Process	GO:0034097	response to cytokine	Traf3ip2	IMP	MGI:MGI:3510784	Mouse	PMID:19155512
Biological Process	GO:0009410	response to xenobiotic stimulus	Traf3ip2	IMP	MGI:MGI:3831153	Mouse	PMID:19155511
Biological Process	GO:0023019	signal transduction involved in regulation of gene expression	Traf3ip2	IDA		Mouse	PMID:21822258
Biological Process	GO:0043588	skin development	Traf3ip2	IMP	MGI:MGI:4820827	Mouse	PMID:20660351
Biological Process	GO:0048536	spleen development	Traf3ip2	IMP	MGI:MGI:3510784	Mouse	PMID:22585710
Biological Process	GO:0042110	T cell activation	Traf3ip2	IMP	MGI:MGI:3510784	Mouse	PMID:20303295
Biological Process	GO:0030217	T cell differentiation	Traf3ip2	IMP	MGI:MGI:3510784	Mouse	PMID:22585710
Biological Process	GO:0072538	T-helper 17 type immune response	Traf3ip2	IDA		Mouse	PMID:28561022
Biological Process	GO:0002334	transitional two stage B cell differentiation	Traf3ip2	IMP	MGI:MGI:3510784	Mouse	PMID:20543113
Biological Process	GO:0033209	tumor necrosis factor-mediated signaling pathway	Traf3ip2	IGI	MGI:MGI:1344376	Mouse	PMID:18624351
Biological Process	GO:0042092	type 2 immune response	Traf3ip2	IMP	MGI:MGI:3510784	Mouse	PMID:21856933

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/07/2024 MGI 6.23

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.