Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TMPRSS4
  • Mouse genes Tmprss4
  • Rat genes Tmprss4
  • Zfish genes tmprss4a,tmprss4b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tmprss4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TMPRSS4	IPI	UniProtKB:Q8N6L0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TMPRSS4	IPI	UniProtKB:Q9BSE2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TMPRSS4	IPI	UniProtKB:O60238	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMPRSS4	IPI	UniProtKB:P58418	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMPRSS4	IPI	UniProtKB:P60508	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMPRSS4	IPI	UniProtKB:Q5JX71	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMPRSS4	IPI	UniProtKB:Q8TBE3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMPRSS4	IPI	UniProtKB:Q8TDF6-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMPRSS4	IPI	UniProtKB:Q8TED1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMPRSS4	IPI	UniProtKB:Q96L08	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMPRSS4	IPI	UniProtKB:Q96PQ1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMPRSS4	IPI	UniProtKB:P48730-2	Human	PMID:32814053
Molecular Function	GO:0008236	serine-type peptidase activity	TMPRSS4	IDA		Human	PMID:24434139
Cellular Component	GO:0005615	extracellular space	TMPRSS4	IDA		Human	PMID:24434139
Cellular Component	GO:0030141	secretory granule	TMPRSS4	IDA		Human	PMID:29529050
Cellular Component	GO:0030141	secretory granule	Tmprss4	IDA		Mouse	PMID:29529050
Biological Process	GO:0045967	negative regulation of growth rate	TMPRSS4	IDA		Human	PMID:29529050
Biological Process	GO:0046598	positive regulation of viral entry into host cell	TMPRSS4	IDA		Human	PMID:32404436
Biological Process	GO:0016485	protein processing	TMPRSS4	IDA		Human	PMID:24434139
Biological Process	GO:0006508	proteolysis	TMPRSS4	IDA		Human	PMID:24434139
Biological Process	GO:0010468	regulation of gene expression	TMPRSS4	IDA		Human	PMID:29529050
Biological Process	GO:0009611	response to wounding	Tmprss4	IMP	MGI:MGI:5007384	Mouse	PMID:29529050

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern