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Tmprss4 Gene Detail
Summary
  • Symbol
    Tmprss4
  • Name
    transmembrane protease, serine 4
  • Synonyms
    MGC:29209
  • Feature Type
    protein coding gene
  • IDs
    MGI:2384877
    NCBI Gene: 214523
Location & Maps
more
  • Sequence Map
    Chr9:45172726-45204092 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      31367 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 24.84 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    TMPRSS4, transmembrane protease, serine 4
  • Vertebrate Orthologs
    11
  • Human Ortholog
    TMPRSS4, transmembrane protease, serine 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CAPH2, MT-SP2, TMPRSS3
  • Links
    NCBI Gene ID: 56649
    neXtProt AC: NX_Q9NRS4

  • Chr Location
    11q23.3; chr11:118077012-118125505 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000036044 VEGA Gene Model | MGI Sequence Detail 31367 C57BL/6J ±  kb
transcript OTTMUST00000092526 VEGA | MGI Sequence Detail 2284 Not Applicable  
polypeptide OTTMUSP00000051154 VEGA | MGI Sequence Detail 435 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    600 from dbSNP Build 142
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000016458 transmembrane protease serine 4
  • EC
  • InterPro Domains
    IPR002172 Low-density lipoprotein (LDL) receptor class A repeat
    IPR001314 Peptidase S1A, chymotrypsin family
    IPR009003 Peptidase S1, PA clan
    IPR001254 Serine proteases, trypsin domain
    IPR018114 Serine proteases, trypsin family, histidine active site
    IPR033116 Serine proteases, trypsin family, serine active site
    IPR001190 SRCR domain
    IPR017448 SRCR-like domain
Molecular
Reagents
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  • All nucleic 35
    cDNA 34
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 25
    Developmental Gene Expression 4
    Gene Ontology 2
    Phenotypes 4
  • Earliest
    J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. http://www.gudmap.org. 2004;
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/13/2016
MGI 6.05
The Jackson Laboratory