Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TEAD4
  • Mouse genes Tead4
  • Rat genes Tead4
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tead4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Tead4	IDA		Mouse	PMID:8702974
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Tead4	IDA		Mouse	MGI:MGI:3608264|PMID:16207754
Molecular Function	GO:0003700	DNA-binding transcription factor activity	TEAD4	IDA		Human	PMID:18579750
Molecular Function	GO:0003700	DNA-binding transcription factor activity	TEAD4	IDA		Human	PMID:19324877
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Tead4	IDA		Mouse	PMID:26902285
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:Q9GZV5	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:P46937	Human	PMID:18579750
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:Q9GZV5	Human	PMID:19324877
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:Q9GZV5	Human	PMID:20972459
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:Q53EZ4	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:P46937	Human	PMID:24525233
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:Q14135	Human	PMID:24525233
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:Q80V24	Human	PMID:24525233
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:P46937	Human	PMID:25751139
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:P46937	Human	PMID:25751140
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:P08237	Human	PMID:25796446
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:P46937	Human	PMID:26592798
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:P0C7W6	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:P14373	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:Q08379	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:Q13077	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:Q59EK9-3	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:Q5JR59-3	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:Q6A162	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:Q8IX15-3	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:Q8N1B4	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:Q8ND90	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:P15884	Human	PMID:28051067
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:Q9GZV5	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:Q9NP79	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:Q53EZ4	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:Q9GZV5	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:A6NEM1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:A6NK89	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:A8MV65-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:O60504	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:O95751	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:P14373	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:P21673	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:P31321	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:Q01196-8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:Q01850	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:Q08117-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:Q08379	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:Q0VD86	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:Q13077	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:Q15323	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:Q53EZ4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:Q5JR59-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:Q6A162	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:Q7Z3Y8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:Q86VW0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:Q86Z20	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:Q8WWB3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:Q96CS2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:Q99990	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:Q9BRK4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:Q9BYV2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:Q9GZV5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:Q9GZV8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TEAD4	IPI	UniProtKB:Q9NP79	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Tead4	IPI	UniProtKB:Q99NC0	Mouse	MGI:MGI:5926794|PMID:22632831
Molecular Function	GO:0005515	protein binding	Tead4	IPI	UniProtKB:Q80V24	Mouse	MGI:MGI:5616280|PMID:24525233
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Tead4	IDA		Mouse	MGI:MGI:3608264|PMID:16207754
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Tead4	IDA		Mouse	PMID:8702974
Molecular Function	GO:0043565	sequence-specific DNA binding	Tead4	IDA		Mouse	PMID:22529382
Cellular Component	GO:0005737	cytoplasm	Tead4	IDA		Mouse	PMID:22529382
Cellular Component	GO:0005654	nucleoplasm	TEAD4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	TEAD4	IDA		Human	PMID:25796446
Cellular Component	GO:0032993	protein-DNA complex	Tead4	IDA		Mouse	PMID:22529382
Cellular Component	GO:0005667	transcription regulator complex	Tead4	IDA		Mouse	PMID:16207754
Biological Process	GO:0001825	blastocyst formation	Tead4	IMP	MGI:MGI:3763362	Mouse	PMID:18804437
Biological Process	GO:0045165	cell fate commitment	Tead4	IDA		Mouse	PMID:22529382
Biological Process	GO:0001708	cell fate specification	Tead4	IMP	MGI:MGI:106907	Mouse	PMID:18083014
Biological Process	GO:0007566	embryo implantation	Tead4	IMP	MGI:MGI:106907	Mouse	PMID:18083014
Biological Process	GO:0035329	hippo signaling	TEAD4	IDA		Human	PMID:18579750
Biological Process	GO:0035329	hippo signaling	TEAD4	IDA		Human	PMID:19324877
Biological Process	GO:0001701	in utero embryonic development	Tead4	IMP	MGI:MGI:106907	Mouse	PMID:18083014
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Tead4	IDA		Mouse	PMID:26902285
Biological Process	GO:1902459	positive regulation of stem cell population maintenance	Tead4	IGI	MGI:MGI:101876	Mouse	PMID:20516196
Biological Process	GO:1902459	positive regulation of stem cell population maintenance	Tead4	IGI	MGI:MGI:109241	Mouse	PMID:20516196
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Tead4	IDA		Mouse	MGI:MGI:3608264|PMID:16207754
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Tead4	IMP		Mouse	PMID:22529382
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Tead4	IGI	MGI:MGI:103262	Mouse	PMID:16207754
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Tead4	IMP	MGI:MGI:106907	Mouse	PMID:18083014
Biological Process	GO:0001830	trophectodermal cell fate commitment	Tead4	IMP	MGI:MGI:106907	Mouse	PMID:18083014

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern