Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Tbp

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes TBP
- Mouse genes Tbp
- Rat genes Tbp
- Zfish genes tbp
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tbp

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0017162	aryl hydrocarbon receptor binding	TBP	IPI	UniProtKB:P35869	Human	PMID:15641800
Molecular Function	GO:0001046	core promoter sequence-specific DNA binding	TBP	IDA		Human	PMID:9841876
Molecular Function	GO:0003677	DNA binding	Tbp	IDA		Mouse	PMID:18722179
Molecular Function	GO:0003677	DNA binding	Tbp	IDA		Mouse	PMID:18218637
Molecular Function	GO:0003677	DNA binding	Tbp	IDA		Mouse	PMID:15601870
Molecular Function	GO:0003677	DNA binding	Tbp	IDA		Rat	PMID:16112330\|RGD:5684346
Molecular Function	GO:0003677	DNA binding	tbp	IDA		Zfish	PMID:18046332\|ZFIN:ZDB-PUB-071210-9
Molecular Function	GO:0140297	DNA-binding transcription factor binding	TBP	IPI	UniProtKB:Q00613	Human	PMID:11005381
Molecular Function	GO:0140297	DNA-binding transcription factor binding	TBP	IPI	UniProtKB:P05412	Human	PMID:12676957
Molecular Function	GO:0140297	DNA-binding transcription factor binding	TBP	IPI	UniProtKB:Q9ULM3	Human	PMID:18838386
Molecular Function	GO:0140297	DNA-binding transcription factor binding	TBP	IPI	UniProtKB:Q12947	Human	PMID:9722567
Molecular Function	GO:0019899	enzyme binding	TBP	IPI	UniProtKB:Q9UKV8	Human	PMID:25336585
Molecular Function	GO:0019899	enzyme binding	TBP	IPI	UniProtKB:Q9UL18	Human	PMID:25336585
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:P78545	Human	PMID:10391676
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:O60869-1	Human	PMID:10567391
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:Q00403	Human	PMID:10619841
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:P20265	Human	PMID:11029584
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:Q5VWG9	Human	PMID:11438666
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:O60869	Human	PMID:12040021
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:Q8IZX4	Human	PMID:12217962
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:P87662	Human	PMID:12552007
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:P04637	Human	PMID:1465435
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:P20226	Human	PMID:15207618
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:Q00403	Human	PMID:15207618
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:Q05906	Human	PMID:15207618
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:P17473	Human	PMID:16641295
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:P18111	Human	PMID:17158164
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:Q16514	Human	PMID:17158164
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:Q15572	Human	PMID:17268553
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:Q16514	Human	PMID:17268553
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:Q01105	Human	PMID:17318177
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:Q15572	Human	PMID:17318177
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:Q15573	Human	PMID:17318177
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:Q53T94	Human	PMID:17318177
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:P21675	Human	PMID:17884155
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:P21675	Human	PMID:18391197
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:P28159	Human	PMID:21653638
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:L8B1Q7	Human	PMID:24418534
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:Q5NTY3	Human	PMID:24418534
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:Q15573	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:Q53T94	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:P52655	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:Q00535	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:Q16236	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:P49848-1	Human	PMID:7667268
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:P21675	Human	PMID:7680771
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:P52657	Human	PMID:7724559
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:P21675	Human	PMID:7729427
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:Q15544	Human	PMID:7729427
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:Q16514	Human	PMID:7729427
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:P04637	Human	PMID:7799929
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:P09429	Human	PMID:8006019
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:P52655	Human	PMID:8006019
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:Q00403	Human	PMID:8006019
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:Q00403	Human	PMID:8504927
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:P52657	Human	PMID:8626665
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:Q15542	Human	PMID:9045704
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:P21675	Human	PMID:9603525
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:Q16514	Human	PMID:9603525
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:P21675	Human	PMID:9674425
Molecular Function	GO:0005515	protein binding	TBP	IPI	UniProtKB:Q5T230	Human	PMID:9748258
Molecular Function	GO:0005515	protein binding	Tbp	IPI	UniProtKB:Q6J1H4	Mouse	MGI:MGI:1202493\|PMID:9524124
Molecular Function	GO:0005515	protein binding	Tbp	IPI	UniProtKB:O35740	Mouse	MGI:MGI:5009206\|PMID:10593900
Molecular Function	GO:0005515	protein binding	Tbp	IPI	UniProtKB:P97357	Mouse	PMID:28893950
Molecular Function	GO:0005515	protein binding	Tbp	IPI	UniProtKB:Q6PDZ2	Mouse	PMID:28893950
Molecular Function	GO:0005515	protein binding	Tbp	IPI	PR:Q8C5D8	Mouse	PMID:16522640
Molecular Function	GO:0005515	protein binding	Tbp	IPI	PR:Q9JM05	Mouse	PMID:16522640
Molecular Function	GO:0005515	protein binding	Tbp	IPI	PR:Q9R1C0	Mouse	PMID:12665565
Molecular Function	GO:0005515	protein binding	Tbp	IPI	PR:Q6PDZ2	Mouse	PMID:9050847
Molecular Function	GO:0005515	protein binding	Tbp	IPI	PR:Q6NXH3	Mouse	PMID:14612417
Molecular Function	GO:0005515	protein binding	Tbp	IPI	PR:Q9R1C0	Mouse	PMID:17242199
Molecular Function	GO:0005515	protein binding	Tbp	IPI	MGI:MGI:2152346	Mouse	PMID:12665565
Molecular Function	GO:0005515	protein binding	Tbp	IPI	PR:P07903	Mouse	PMID:22323595
Molecular Function	GO:0005515	protein binding	Tbp	IPI	PR:Q9D3R9	Mouse	PMID:17242199
Molecular Function	GO:0005515	protein binding	Tbp	IPI	PR:P97357	Mouse	PMID:9050847
Molecular Function	GO:0005515	protein binding	Tbp	IPI	PR:Q8BMU0	Mouse	PMID:16522640
Molecular Function	GO:0005515	protein binding	Tbp	IPI	PR:Q9D3R9	Mouse	PMID:12665565
Molecular Function	GO:0005515	protein binding	Tbp	IPI	PR:O88907	Mouse	PMID:16522640
Molecular Function	GO:0005515	protein binding	Tbp	IPI	PR:Q62311	Mouse	PMID:12665565
Molecular Function	GO:0005515	protein binding	Tbp	IPI	PR:P97358	Mouse	PMID:9050847
Molecular Function	GO:0005515	protein binding	Tbp	IPI	RGD:620366	Rat	PMID:10471789\|RGD:632913
Molecular Function	GO:0005515	protein binding	Tbp	IPI	UniProtKB:P26663	Rat	PMID:12379483\|RGD:9681731
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Tbp	IDA		Mouse	PMID:22194471
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Tbp	IDA		Mouse	PMID:21245044
Molecular Function	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	TBP	IDA		Human	PMID:29111974
Molecular Function	GO:0016251	RNA polymerase II general transcription initiation factor activity	TBP	IDA		Human	PMID:27193682
Molecular Function	GO:0016251	RNA polymerase II general transcription initiation factor activity	TBP	IDA		Human	PMID:9841876
Molecular Function	GO:0016251	RNA polymerase II general transcription initiation factor activity	Tbp	IDA		Rat	PMID:7980586\|RGD:2306552
Molecular Function	GO:0001091	RNA polymerase II general transcription initiation factor binding	TBP	IPI	UniProtKB:P52655	Human	PMID:29111974
Molecular Function	GO:0001091	RNA polymerase II general transcription initiation factor binding	TBP	IPI	UniProtKB:Q15543	Human	PMID:29111974
Molecular Function	GO:0001091	RNA polymerase II general transcription initiation factor binding	TBP	IPI	UniProtKB:Q15544	Human	PMID:29111974
Molecular Function	GO:0001091	RNA polymerase II general transcription initiation factor binding	TBP	IPI	UniProtKB:P52655	Human	PMID:7724559
Molecular Function	GO:0001091	RNA polymerase II general transcription initiation factor binding	TBP	IPI	UniProtKB:P52657	Human	PMID:7724559
Molecular Function	GO:0001091	RNA polymerase II general transcription initiation factor binding	TBP	IPI	UniProtKB:P52657	Human	PMID:8626665
Molecular Function	GO:0001091	RNA polymerase II general transcription initiation factor binding	TBP	IPI	UniProtKB:Q01658	Human	PMID:8670811
Molecular Function	GO:0001091	RNA polymerase II general transcription initiation factor binding	TBP	IPI	UniProtKB:Q14919	Human	PMID:8670811
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	Tbp	IPI	PR:Q8BIA3	Mouse	PMID:19235719
Molecular Function	GO:0000995	RNA polymerase III general transcription initiation factor activity	TBP	IMP		Human	PMID:26638071
Molecular Function	GO:0001093	TFIIB-class transcription factor binding	TBP	IPI	UniProtKB:Q00403	Human	PMID:9841876
Molecular Function	GO:0000976	transcription cis-regulatory region binding	TBP	IDA		Human	PMID:16540471
Molecular Function	GO:0000976	transcription cis-regulatory region binding	TBP	IDA		Human	PMID:7933101
Molecular Function	GO:0000976	transcription cis-regulatory region binding	TBP	IDA		Human	PMID:9027316
Cellular Component	GO:0000785	chromatin	TBP	IDA		Human	PMID:24289924
Cellular Component	GO:0005737	cytoplasm	Tbp	IDA		Mouse	PMID:12665565
Cellular Component	GO:0000791	euchromatin	TBP	IDA		Human	PMID:19861239
Cellular Component	GO:0001674	female germ cell nucleus	Tbp	IDA		Mouse	PMID:17641088
Cellular Component	GO:0001939	female pronucleus	Tbp	IDA		Mouse	PMID:17641088
Cellular Component	GO:0001673	male germ cell nucleus	Tbp	IDA		Mouse	PMID:12665565
Cellular Component	GO:0001940	male pronucleus	Tbp	IDA		Mouse	PMID:17641088
Cellular Component	GO:0005654	nucleoplasm	TBP	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	TBP	EXP		Human	PMID:23332750
Cellular Component	GO:0005634	nucleus	TBP	IDA		Human	PMID:27007846
Cellular Component	GO:0005634	nucleus	TBP	IDA		Human	PMID:9841876
Cellular Component	GO:0005634	nucleus	Tbp	IPI	PR:P07903	Mouse	PMID:22323595
Cellular Component	GO:0005634	nucleus	Tbp	IDA		Mouse	PMID:17242199
Cellular Component	GO:0005634	nucleus	Tbp	IDA		Mouse	PMID:16522640
Cellular Component	GO:0005634	nucleus	Tbp	IDA		Mouse	PMID:22194471
Cellular Component	GO:0005634	nucleus	Tbp	IDA		Mouse	PMID:11861477
Cellular Component	GO:0005634	nucleus	Tbp	IDA		Mouse	PMID:12411709
Cellular Component	GO:0005634	nucleus	Tbp	IDA		Mouse	PMID:17641088
Cellular Component	GO:0005634	nucleus	Tbp	IDA		Mouse	PMID:15927180
Cellular Component	GO:0005634	nucleus	Tbp	IDA		Mouse	PMID:22323595
Cellular Component	GO:0005634	nucleus	Tbp	IDA		Mouse	PMID:12471023
Cellular Component	GO:0005634	nucleus	Tbp	IDA		Mouse	PMID:18722179
Cellular Component	GO:0005634	nucleus	Tbp	IDA		Rat	PMID:7980586\|RGD:2306552
Cellular Component	GO:0045120	pronucleus	Tbp	IDA		Mouse	PMID:16822332
Cellular Component	GO:0032991	protein-containing complex	TBP	IMP		Human	PMID:15641800
Cellular Component	GO:0005668	RNA polymerase transcription factor SL1 complex	Tbp	IPI	UniProtKB:P97357	Mouse	PMID:28893950
Cellular Component	GO:0005668	RNA polymerase transcription factor SL1 complex	Tbp	IPI	UniProtKB:Q6PDZ2	Mouse	PMID:28893950
Cellular Component	GO:0005672	transcription factor TFIIA complex	TBP	IDA		Human	PMID:7724559
Cellular Component	GO:0005669	transcription factor TFIID complex	TBP	IPI		Human	PMID:23332750
Cellular Component	GO:0005669	transcription factor TFIID complex	TBP	IDA		Human	PMID:14580349
Cellular Component	GO:0005669	transcription factor TFIID complex	TBP	IDA		Human	PMID:27007846
Cellular Component	GO:0005669	transcription factor TFIID complex	TBP	IDA		Human	PMID:27193682
Cellular Component	GO:0005669	transcription factor TFIID complex	TBP	IDA		Human	PMID:29111974
Cellular Component	GO:0005669	transcription factor TFIID complex	TBP	IDA		Human	PMID:7729427
Cellular Component	GO:0005669	transcription factor TFIID complex	Tbp	IDA		Mouse	PMID:28893950
Cellular Component	GO:0005669	transcription factor TFIID complex	Tbp	IDA		Rat	PMID:7980586\|RGD:2306552
Biological Process	GO:0007369	gastrulation	tbp	IMP		Zfish	PMID:18046332\|ZFIN:ZDB-PUB-071210-9
Biological Process	GO:0006402	mRNA catabolic process	tbp	IMP		Zfish	PMID:17703193\|ZFIN:ZDB-PUB-070820-19
Biological Process	GO:0042789	mRNA transcription by RNA polymerase II	TBP	IDA		Human	PMID:17884155
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Tbp	IDA		Rat	PMID:7980586\|RGD:2306552
Biological Process	GO:0060261	positive regulation of transcription initiation by RNA polymerase II	TBP	IDA		Human	PMID:17884155
Biological Process	GO:0006468	protein phosphorylation	TBP	IDA		Human	PMID:15053879
Biological Process	GO:0051123	RNA polymerase II preinitiation complex assembly	TBP	IPI		Human	PMID:27007846
Biological Process	GO:0051123	RNA polymerase II preinitiation complex assembly	TBP	IDA		Human	PMID:9841876
Biological Process	GO:0007283	spermatogenesis	Tbp	IEP		Rat	PMID:8776734\|RGD:2306551
Biological Process	GO:0006366	transcription by RNA polymerase II	TBP	IMP		Human	PMID:27193682
Biological Process	GO:0006366	transcription by RNA polymerase II	TBP	IDA		Human	PMID:7724559
Biological Process	GO:0006366	transcription by RNA polymerase II	Tbp	IMP	MGI:MGI:2429772	Mouse	PMID:12411709
Biological Process	GO:0006366	transcription by RNA polymerase II	tbp	IMP		Zfish	PMID:11250159\|ZFIN:ZDB-PUB-010404-14
Biological Process	GO:0006366	transcription by RNA polymerase II	tbp	IMP		Zfish	PMID:17703193\|ZFIN:ZDB-PUB-070820-19
Biological Process	GO:0006366	transcription by RNA polymerase II	tbp	IMP	ZFIN:ZDB-MRPHLNO-071129-3	Zfish	PMID:11250159
Biological Process	GO:0006383	transcription by RNA polymerase III	TBP	IDA		Human	PMID:9027316
Biological Process	GO:0006383	transcription by RNA polymerase III	TBP	IMP		Human	PMID:26638071
Biological Process	GO:0006383	transcription by RNA polymerase III	Tbp	IMP	MGI:MGI:2429772	Mouse	PMID:12411709

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/25/2025 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.