Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Spry1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes SPRY1
- Mouse genes Spry1
- Rat genes Spry1
- Zfish genes spry1
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Spry1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:P57678	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:P09022	Human	PMID:23088713
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:O43597	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:P32242	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:P49639	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:P50222	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:P60370	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:P60409	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:P60410	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:P60411	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q02930-3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q5T7P3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q5TA82	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q7Z3S9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q96MH2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q99750	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q9BYR5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q9Y2K5-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:P32242	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:P50222	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q5TA82	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q7Z3S9	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:O15160	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:O43184-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:O43741	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:O75031	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:O95363	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:P0DPK4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:P17027	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:P23142-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:P26371	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:P49639	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:P49901	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:P54646	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:P57075-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:P57678	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:P59991	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:P60328	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:P60409	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:P60410	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:P60411	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:P60412	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q02930-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q04864-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q07627	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q0VD86	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q15323	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q2TAC2-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q2TAL6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q5T5A8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q5T749	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q5T751	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q5T752	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q5T754	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q5T7P2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q5TA76	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q5TA78	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q5TA79	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q5TA81	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q5TA82	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q5TCM9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q5TD97	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q6UY14-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q7Z6R9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q86X02	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q8IUC1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q8IUG1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q8IYB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q8N8Z8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q8TAU3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q92824-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q96EG3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q96NT3-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q96PF1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q99750	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q9BQ66	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q9BYE3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q9BYQ3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q9BYQ4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q9BYR7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q9H2X0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q9P121-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q9Y223-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:Q9Y3S2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY1	IPI	UniProtKB:X5D778	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Spry1	IPI	UniProtKB:Q63572	Mouse	MGI:MGI:3771987\|PMID:17974561
Molecular Function	GO:0005515	protein binding	Spry1	IPI	UniProtKB:P49817\|UniProtKB:Q9QXV8	Mouse	MGI:MGI:3695236\|PMID:16877379
Molecular Function	GO:0005515	protein binding	Spry1	IPI	PR:Q9WTP2	Mouse	PMID:16339969
Molecular Function	GO:0005515	protein binding	Spry1	IPI	MGI:MGI:1345188	Mouse	PMID:16339969
Molecular Function	GO:0005515	protein binding	Spry1	IPI	PR:Q9QXV8	Mouse	PMID:16339969
Molecular Function	GO:0005515	protein binding	Spry1	IPI	PR:Q9QXV9	Mouse	PMID:16339969
Molecular Function	GO:0005515	protein binding	Spry1	IPI	PR:Q60631	Mouse	PMID:16339969
Cellular Component	GO:0005829	cytosol	SPRY1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Spry1	IDA		Rat	PMID:23441172\|RGD:10400865
Cellular Component	GO:0005794	Golgi apparatus	SPRY1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	SPRY1	IDA		Human	GO_REF:0000052
Biological Process	GO:0060449	bud elongation involved in lung branching	Spry1	IGI	MGI:MGI:1099809	Mouse	PMID:21764747
Biological Process	GO:0060449	bud elongation involved in lung branching	Spry1	IGI	MGI:MGI:1345138	Mouse	PMID:21764747
Biological Process	GO:0060940	epithelial to mesenchymal transition involved in cardiac fibroblast development	Spry1	IGI	RNAcentral:URS000039ED8D_10116	Rat	PMID:23441172\|RGD:10400865
Biological Process	GO:0070371	ERK1 and ERK2 cascade	Spry1	IGI	MGI:MGI:1099809	Mouse	PMID:21764747
Biological Process	GO:0070371	ERK1 and ERK2 cascade	Spry1	IGI	MGI:MGI:1345138	Mouse	PMID:21764747
Biological Process	GO:0000132	establishment of mitotic spindle orientation	Spry1	IGI	MGI:MGI:1345138	Mouse	PMID:21764747
Biological Process	GO:0000132	establishment of mitotic spindle orientation	Spry1	IGI	MGI:MGI:1099809	Mouse	PMID:21764747
Biological Process	GO:0001656	metanephros development	Spry1	IGI	MGI:MGI:109442	Mouse	PMID:17537792
Biological Process	GO:0008285	negative regulation of cell population proliferation	Spry1	IDA		Mouse	PMID:11585837
Biological Process	GO:0010719	negative regulation of epithelial to mesenchymal transition	Spry1	IDA		Mouse	MGI:MGI:6414689\|PMID:25576668
Biological Process	GO:0070373	negative regulation of ERK1 and ERK2 cascade	Spry1	IDA		Mouse	MGI:MGI:6414698\|PMID:29501879
Biological Process	GO:0070373	negative regulation of ERK1 and ERK2 cascade	Spry1	IMP		Mouse	MGI:MGI:3831894\|PMID:19043405
Biological Process	GO:0070373	negative regulation of ERK1 and ERK2 cascade	Spry1	IGI	MGI:MGI:1345138	Mouse	PMID:21764747
Biological Process	GO:0070373	negative regulation of ERK1 and ERK2 cascade	Spry1	IDA		Mouse	PMID:11585837
Biological Process	GO:0070373	negative regulation of ERK1 and ERK2 cascade	Spry1	IGI	MGI:MGI:1099809	Mouse	PMID:21764747
Biological Process	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	SPRY1	IMP		Human	PMID:16481357
Biological Process	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	Spry1	IDA		Mouse	PMID:11585837
Biological Process	GO:0034260	negative regulation of GTPase activity	Spry1	IDA		Mouse	PMID:11585837
Biological Process	GO:1902747	negative regulation of lens fiber cell differentiation	Spry1	IDA		Mouse	MGI:MGI:6414698\|PMID:29501879
Biological Process	GO:0043407	negative regulation of MAP kinase activity	Spry1	IDA		Mouse	PMID:16339969
Biological Process	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway	Spry1	IDA		Mouse	PMID:11585837
Biological Process	GO:0046580	negative regulation of Ras protein signal transduction	Spry1	IDA		Mouse	PMID:11585837
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	Spry1	IDA		Mouse	MGI:MGI:6414689\|PMID:25576668
Biological Process	GO:0001759	organ induction	Spry1	IMP	MGI:MGI:3574404	Mouse	PMID:15691764
Biological Process	GO:0043065	positive regulation of apoptotic process	Spry1	IMP		Rat	PMID:30515805\|RGD:40925948
Biological Process	GO:0001657	ureteric bud development	Spry1	IMP	MGI:MGI:3574404	Mouse	PMID:15691764
Biological Process	GO:0001657	ureteric bud development	Spry1	IGI	MGI:MGI:107430	Mouse	PMID:15691764

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/14/2024 MGI 6.23

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.