Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SERPINC1
  • Mouse genes Serpinc1
  • Rat genes Serpinc1
  • Zfish genes serpinc1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Serpinc1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008201	heparin binding	Serpinc1	IDA		Rat	PMID:7362830|RGD:1599342
Molecular Function	GO:0042802	identical protein binding	SERPINC1	IPI	UniProtKB:P01008	Human	PMID:18923394
Molecular Function	GO:0002020	protease binding	SERPINC1	IPI	UniProtKB:Q8BIK6	Human	PMID:15853774
Molecular Function	GO:0005515	protein binding	SERPINC1	IPI	UniProtKB:Q92876	Human	PMID:12878203
Molecular Function	GO:0005515	protein binding	SERPINC1	IPI	UniProtKB:Q8IXL6	Human	PMID:22582013
Molecular Function	GO:0005515	protein binding	Serpinc1	IPI	UniProtKB:P00735	Rat	PMID:7362830|RGD:1599342
Molecular Function	GO:0004867	serine-type endopeptidase inhibitor activity	Serpinc1	IDA		Rat	PMID:7362830|RGD:1599342
Cellular Component	GO:0072562	blood microparticle	SERPINC1	HDA		Human	PMID:22516433
Cellular Component	GO:0062023	collagen-containing extracellular matrix	SERPINC1	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	SERPINC1	HDA		Human	PMID:28675934
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Serpinc1	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0070062	extracellular exosome	SERPINC1	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	SERPINC1	HDA		Human	PMID:16502470
Cellular Component	GO:0005615	extracellular space	SERPINC1	IDA		Human	PMID:1695900
Cellular Component	GO:0005615	extracellular space	Serpinc1	IDA		Rat	PMID:7930519|RGD:1599338
Biological Process	GO:0002438	acute inflammatory response to antigenic stimulus	Serpinc1	IEP		Rat	PMID:17850787|RGD:11035259
Biological Process	GO:0071391	cellular response to estrogen stimulus	serpinc1	IDA		Zfish	PMID:18618001
Biological Process	GO:0007595	lactation	Serpinc1	IEP		Rat	PMID:22776112|RGD:11035275
Biological Process	GO:0030193	regulation of blood coagulation	serpinc1	IMP	ZFIN:ZDB-GENO-150909-1	Zfish	PMID:24782510
Biological Process	GO:0007584	response to nutrient	Serpinc1	IDA		Rat	PMID:17123684|RGD:1599322

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern